Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hannah Botfield"'
Autor:
Sonia Podvin, Ana-Maria Gonzalez, Miles C Miller, Xitong Dang, Hannah Botfield, John E Donahue, Arwa Kurabi, Matthew Boissaud-Cooke, Ryan Rossi, Wendy E Leadbeater, Conrad E Johanson, Raul Coimbra, Edward G Stopa, Brian P Eliceiri, Andrew Baird
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24609 (2011)
By virtue of its ability to regulate the composition of cerebrospinal fluid (CSF), the choroid plexus (CP) is ideally suited to instigate a rapid response to traumatic brain injury (TBI) by producing growth regulatory proteins. For example, Esophagea
Externí odkaz:
https://doaj.org/article/d52375a279d04f549262994acb27c486
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
Supplementary Figures 1-3 from A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252e17f4b68a6b0f1e22abea11485381
https://doi.org/10.1158/0008-5472.22381802.v1
https://doi.org/10.1158/0008-5472.22381802.v1
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
Supplementary Figure Legends 1-13, Methods from A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d6877077a5946fd581adf28f4f9f33
https://doi.org/10.1158/0008-5472.22381805
https://doi.org/10.1158/0008-5472.22381805
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
Supplementary Figure 13 from A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba64325f26ecef3f42e9bfd84f0b9520
https://doi.org/10.1158/0008-5472.22381814
https://doi.org/10.1158/0008-5472.22381814
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
Supplementary Figures 6-9 from A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2f8c3413d8e42c97e94fbfeb8b00fb
https://doi.org/10.1158/0008-5472.22381799
https://doi.org/10.1158/0008-5472.22381799
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
Supplementary Figure 4 from A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310c302b7867920ee9d2a78e201ead55
https://doi.org/10.1158/0008-5472.22381811
https://doi.org/10.1158/0008-5472.22381811
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
The Wnt signaling pathway is frequently deregulated in cancer due to mutations in genes encoding APC, β-catenin, and axin. To identify small-molecule inhibitors of Wnt signaling as potential therapeutics, a diverse chemical library was screened usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e0ec665076de7d4d85630ffe3393c6
https://doi.org/10.1158/0008-5472.c.6499982.v1
https://doi.org/10.1158/0008-5472.c.6499982.v1
Autor:
Trevor Dale, Wynne Aherne, Julian Blagg, Edward McDonald, Paul Workman, Branko Latinkic, Stephen Wilson, Nicholas Allen, Florence Raynaud, Alysia Battersby, Lee Samuel, Ruth Ruddle, Rodrigo Young, Hannah Botfield, Camilo Quevedo, Olivier Barbeau, Helen Todd, Mark Stubbs, Bożena Pająk, Kenneth Ewan
Supplementary Figure 5 from A Useful Approach to Identify Novel Small-Molecule Inhibitors of Wnt-Dependent Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e2261ae997cd9c76e7200ee0747ece
https://doi.org/10.1158/0008-5472.22381808.v1
https://doi.org/10.1158/0008-5472.22381808.v1
Autor:
Connar Westgate, Gareth G. Lavery, Alexandra J Sinclair, Michael Sagmeister, Rebecca J Fairclough, Angela E Taylor, Zerin Alimajstorovic, Susan P Mollan, Hannah Botfield, Andreas Yiangou, James L Mitchell, Wiebke Arlt, Lorna C Gilligan, Keira Markey, Ryan S Ottridge, Paul M. Stewart, Karl-Heinz Storbeck, Rowan Hardy, Jeremy W. Tomlinson
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Background The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) determines prereceptor metabolism and activation of glucocorticoids within peripheral tissues. Its dysregulation has been implicated in a wide array of metabolic diseases, lea
Autor:
Ildem Akerman, Jeremy W. Tomlinson, Rishi Singhal, Daniel A. Tennant, Gabrielle Smith, Daniel Hebenstreit, Zerin Alimajstorovic, Hannah Botfield, Christian Ludwig, Mark D. Walsh, Connar Westgate, James L Mitchell, Keira Markey, Olivia Grech, Susan P Mollan, Andreas Yiangou, Gareth G. Lavery, Alexandra J Sinclair
Publikováno v:
JCI Insight
BACKGROUND Idiopathic intracranial hypertension (IIH) is a condition predominantly affecting obese women of reproductive age. Recent evidence suggests that IIH is a disease of metabolic dysregulation, androgen excess, and an increased risk of cardiov