A randomised controlled trial to investigate the clinical effectiveness and cost effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for depressed non-responders to Increasing Access to Psychological Therapies (IAPT) high-intensity therapies: study protocol

Autor: Thorsten Barnhofer, Barnaby D. Dunn, Clara Strauss, Florian Ruths, Barbara Barrett, Mary Ryan, Asha Ladwa, Frances Stafford, Roberta Fichera, Hannah Baber, Ailis McGuinness, Isabella Metcalfe, Delilah Harding, Sarah Walker, Poushali Ganguli, Shelley Rhodes, Allan Young, Fiona Warren

Publikováno v: Trials, Vol 24, Iss 1, Pp 1-18 (2023)

Abstract Background Major depression represents a pressing challenge for health care. In England, Increasing Access to Psychological Therapies (IAPT) services provide evidence-based psychological therapies in a stepped-care approach to patients with

Externí odkaz: https://doaj.org/article/6b4e3b5db25848ac8075a899959f6426

The Rationale and Design of the Reducing Pathology in Alzheimer’s Disease through Angiotensin TaRgeting (RADAR) Trial

Autor: Yoav Ben-Shlomo, Beth Howden, Jeremy Horwood, Hannah Baber, Ian B. Malone, Athene Lane, Peter S Blair, Lucy E Selman, Ian B. Wilkinson, Clare Clement, Elizabeth Coulthard, Patrick G. Kehoe, Anthony Peter Passmore, Nick C. Fox, David L. Thomas

Publikováno v: Kehoe, P, Ben-Shlomo, Y, Howden, B, Lane, J A, Coulthard, L, Blair, P, Horwood, J, Selman, L & Clement, C 2017, ' The Rationale and Design of the Reducing Pathology in Alzheimer’s Disease through Angiotensin TaRgeting (RADAR) Trial ', Journal of Alzheimer's Disease, vol. 61, no. 2, pp. 803-814 . https://doi.org/10.3233/JAD-170101

Background: Anti-hypertensives that modify the renin angiotensin system may reduce Alzheimer’s disease pathology and reduce the rate of disease progression. We report a phase II, two arm, double-blind, placebo-controlled, randomised trial (ISRCTN:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaedd91e75dcbb8bd35926c11ddc3517
https://doi.org/10.3233/jad-170101