Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hannah A. Grunwald"'
Autor:
Evan A. Boyle, Gabriela Goldberg, Jonathan C. Schmok, Jillybeth Burgado, Fabiana Izidro Layng, Hannah A. Grunwald, Kylie M. Balotin, Michael S. Cuoco, Keng-Chi Chang, Gertrude Ecklu-Mensah, Aleena K. S. Arakaki, Noorsher Ahmed, Ximena Garcia Arceo, Pratibha Jagannatha, Jonathan Pekar, Mallika Iyer, Gene W. Yeo
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/2daee2cf423d405c9100647d96b49732
Autor:
Alexander J Weitzel, Hannah A Grunwald, Ceri Weber, Rimma Levina, Valentino M Gantz, Stephen M Hedrick, Ethan Bier, Kimberly L Cooper
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001478 (2021)
Highly efficient gene conversion systems have the potential to facilitate the study of complex genetic traits using laboratory mice and, if implemented as a "gene drive," to limit loss of biodiversity and disease transmission caused by wild rodent po
Externí odkaz:
https://doaj.org/article/baaab7397acd4441888d4b328da69680
Applications of and considerations for using CRISPR–Cas9-mediated gene conversion systems in rodents
Publikováno v:
Nature Protocols. 17:3-14
Genetic elements that are inherited at super-Mendelian frequencies could be used in a 'gene drive' to spread an allele to high prevalence in a population with the goal of eliminating invasive species or disease vectors. We recently demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29359799c2c6e9c230b92fd3c5edfa0
https://doi.org/10.1038/s41596-021-00646-7
https://doi.org/10.1038/s41596-021-00646-7
Autor:
Rimma Levina, Ethan Bier, Kimberly L. Cooper, Alexander J. Weitzel, Stephen M. Hedrick, Hannah A. Grunwald, Valentino M. Gantz
Highly efficient genotype conversion systems have potential to facilitate the study of complex genetic traits using laboratory mice and to limit loss of biodiversity and disease transmission caused by wild rodent populations. We previously showed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b68d5ebe0e925567e999941eb419cd5e
https://doi.org/10.1101/2021.03.16.435716
https://doi.org/10.1101/2021.03.16.435716
Autor:
Rebecca A.S. Palu, H. Joseph Yost, Xiaoying Bai, Kazuyuki Hoshijima, Haley Jackson, Yi Chu Su, Brent W. Bisgrove, David Grunwald, Alex Nechiporuk, Leonard I. Zon, Hannah A. Grunwald, Michael J. Jurynec
Publikováno v:
Development
Multipotent progenitor populations are necessary for generating diverse tissue types during embryogenesis. We show the Polymerase Associated Factor 1 Complex (Paf1C) is required to maintain multipotent progenitors of the neural crest (NC) lineage in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b5c40986fce48d1b91fe2b6d6e4f5a
https://doi.org/10.1242/dev.180133
https://doi.org/10.1242/dev.180133
Autor:
Kimberly L. Cooper, Gunnar Poplawski, Valentino M. Gantz, Ethan Bier, Hannah A. Grunwald, Xiang-Ru S. Xu
Publikováno v:
Nature
A gene drive biases the transmission of one of two copies of a gene such that it is inherited more frequently than by random segregation. Highly efficient gene drive systems were recently developed in insects, which leverage the sequence-targeted DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93216f12e79e4ffcb7dce9bf1edce35b
https://doi.org/10.1038/s41586-019-1861-4
https://doi.org/10.1038/s41586-019-1861-4
Autor:
Valentino M. Gantz, Gunnar Poplawski, Ethan Bier, Kimberly L. Cooper, Xiang-Ru S. Xu, Hannah A. Grunwald
Publikováno v:
Nature, vol 566, iss 7742
A gene drive biases the transmission of a particular allele of a gene such that it is inherited at a greater frequency than by random assortment. Recently, a highly efficient gene drive was developed in insects, which leverages the sequence-targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1978a596422ef32014e1e421a2427fd1
Autor:
Hannah A, Grunwald, Valentino M, Gantz, Gunnar, Poplawski, Xiang-Ru S, Xu, Ethan, Bier, Kimberly L, Cooper
Publikováno v:
Nature. 566(7742)
A gene drive biases the transmission of one of the two copies of a gene such that it is inherited more frequently than by random segregation. Highly efficient gene drive systems have recently been developed in insects, which leverage the sequence-tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::053c873f521ff789a16a3973439b1841
https://pubmed.ncbi.nlm.nih.gov/31911657
https://pubmed.ncbi.nlm.nih.gov/31911657