Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Hannah A. DeBerg"'
Autor:
Elisa Balmas, Janice Chen, Alex K. Hu, Hannah A. DeBerg, Mario G. Rosasco, Vivian H. Gersuk, Elisavet Serti, Cate Speake, Carla J. Greenbaum, Gerald T. Nepom, Peter S. Linsley, Karen Cerosaletti
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Variation in the preservation of β cell function in clinical trials in type 1 diabetes (T1D) has emphasized the need to define biomarkers to predict treatment response. The T1DAL trial targeted T cells with alefacept (LFA-3–Ig) and demonstrated C-
Externí odkaz:
https://doaj.org/article/fc5124fb6eab4bc1a3e7082177f0b113
Autor:
Alyssa Sheih, Valentin Voillet, Laïla-Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed Hawkins, Vivian Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt, Dnyanada Pande, Mark R. Enstrom, Hans-Peter Kiem, Jennifer E. Adair, Raphaël Gottardo, Peter S. Linsley, Cameron J. Turtle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Understanding factors that impact CAR T cell expansion in the clinic is crucial to improving its therapeutic success. Here the authors document heterogeneity in the clonal dynamics of CAR-T cells by tracking individual clones using the endogenous TCR
Externí odkaz:
https://doaj.org/article/9a5dfb14385d4c6ba59269c0303b6190
Autor:
Peter S. Linsley, Fariba Barahmand-pour-Whitman, Elisa Balmas, Hannah A. DeBerg, Kaitlin J. Flynn, Alex K. Hu, Mario G. Rosasco, Janice Chen, Colin O’Rourke, Elisavet Serti, Vivian H. Gersuk, Keshav Motwani, Howard R. Seay, Todd M. Brusko, William W. Kwok, Cate Speake, Carla J. Greenbaum, Gerald T. Nepom, Karen Cerosaletti
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
Human islet antigen reactive CD4+ memory T cells (IAR T cells) play a key role in the pathogenesis of autoimmune type 1 diabetes (T1D). Using single-cell RNA sequencing (scRNA-Seq) to identify T cell receptors (TCRs) in IAR T cells, we have identifie
Externí odkaz:
https://doaj.org/article/ae78e844c0644847af1e433a33d6fd7d
Autor:
Lynn M. Rose, Hannah A. DeBerg, Prakash Vishnu, Jason K. Frankel, Adarsh B. Manjunath, John Paul E. Flores, David M. Aboulafia
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Checkpoint inhibitors (CPIs) increase antitumor activity by unblocking regulators of the immune response. This action can provoke a wide range of immunologic and inflammatory side effects, some of which can be fatal. Recent studies suggest that CPI-i
Externí odkaz:
https://doaj.org/article/88f695767baf441e8314cd3c5cd60d1f
Publikováno v:
International Journal of Cancer Care and Delivery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb87c3471f2b448996fffec15da13cf4
https://doi.org/10.53876/001c.73728
https://doi.org/10.53876/001c.73728
Autor:
Hannah A DeBerg, Mussaret B Zaidi, Matthew C Altman, Prasong Khaenam, Vivian H Gersuk, Freddy D Campos, Iza Perez-Martinez, Mario Meza-Segura, Damien Chaussabel, Jacques Banchereau, Teresa Estrada-Garcia, Peter S Linsley
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0192082 (2018)
Globally, diarrheal diseases are a leading cause of death in children under five and disproportionately affect children in developing countries. Children who contract diarrheal diseases are rarely screened to identify the etiologic agent due to time
Externí odkaz:
https://doaj.org/article/ec9483f875f64f2ea994a2f03298c003
Autor:
Marcella Ruddy, Pretty Meier, Chengrui Huang, Erik R. Wambre, Matt Cantor, David Robinson, Hannah A. DeBerg, Allen Radin, Michelle DeVeaux, Claire Q. Wang, Veronique Bajzik, Jamie M. Orengo, Mary L. Farrington
Publikováno v:
Clinical & Experimental Allergy. 51:1624-1633
BACKGROUND Characterising the clinical and immunological impact of daily cat exposure in cat-allergic subjects with asthma who live with cats (WC) and those who do not (WoC) may provide understanding of the drivers of the allergic response. METHODS C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc98c8f58da482ba8e181b7ce5bc8ba
https://doi.org/10.1111/cea.14024
https://doi.org/10.1111/cea.14024
Publikováno v:
ImmunoHorizons. 6(3)
Successful treatment of inflammatory bowel disease (IBD) with the anti-integrin α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8fee797b3f558cfc73d8ba62b9d4627
https://pubmed.ncbi.nlm.nih.gov/35273097
https://pubmed.ncbi.nlm.nih.gov/35273097
Autor:
Veronique Bajzik, Hannah A. DeBerg, Nahir Garabatos, Blake J. Rust, Kimberly K. Obrien, Quynh‐Anh Nguyen, Colin O’Rourke, Alex Smith, Alex H. Walker, Charlie Quinn, Vivian H. Gersuk, Mary Farrington, David Jeong, Brian P. Vickery, Daniel C. Adelman, Erik Wambre
Publikováno v:
Allergy. 77(8)
The PALISADE study, an international, phase 3 trial of peanut oral immunotherapy (POIT) with AR101, resulted in desensitization in children and adolescents who were highly allergic to peanut. An improved understanding of the immune mechanism induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a7e2e9605dc19a963caaadaf438831
https://pubmed.ncbi.nlm.nih.gov/35266148
https://pubmed.ncbi.nlm.nih.gov/35266148
Autor:
Gabriele Blahnik, Elisavet Serti, Matthew J. Dufort, Cate Speake, Peter S. Linsley, Hannah A. DeBerg, Anna Kus, Eddie A. James, Bertrand Haas, Scott R. Presnell, Virginia S. Muir, Gerald T. Nepom, Mario G. Rosasco, S. Alice Long, Alice E. Wiedeman, Carla J. Greenbaum
Publikováno v:
Journal of Clinical Investigation. 130:480-490
Although most patients with type 1 diabetes (T1D) retain some functional insulin-producing islet β cells at the time of diagnosis, the rate of further β cell loss varies across individuals. It is not clear what drives this differential progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e0805be8c643ff061e0c39d2cf54cef
https://doi.org/10.1172/jci126595
https://doi.org/10.1172/jci126595