Relevance of dog as an animal model for urologic diseases

Autor: Hannah, Ruetten, Chad M, Vezina

Publikováno v: Progress in molecular biology and translational science. 189(1)

We utilize animal models in urologic research to improve understanding of urinary physiology, determine the etiology of many urologic diseases, and discover and test novel therapeutic interventions. Dogs have a similar urinary tract anatomy and physi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e53ac661573f9cbc261582f935a2c77c
https://pubmed.ncbi.nlm.nih.gov/35595352

Impact of sex, androgens, and prostate size on C57BL/6J mouse urinary physiology: urethral histology

Autor: Hannah Ruetten, Jacquelyn Morkrid, Anne E. Turco, Helen L Zhang, William A. Ricke, Kyle A Wegner, Paul C. Marker, Simran K. Sandhu, Richard E. Peterson, Conner L. Kennedy, Peiqing Wang, Dale E. Bjorling, Chad M. Vezina, Jill A. Macoska, Zunyi Wang, Jaskiran K Sandhu

Publikováno v: Am J Physiol Renal Physiol

The National Institutes of Health leveled new focus on sex as a biological variable with the goal of understanding sex-specific differences in health and physiology. We previously published a functional assessment of the impact of sex, androgens, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2844a1c518ed7f0f3e85953014bbb8
https://doi.org/10.1152/ajprenal.00540.2019

Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation

Autor: Hannah Ruetten, Kristen S. Uchtmann, Chad M. Vezina, Mark Cadena, Kegan O. Skalitzky, William A. Ricke, Asha Jain, Petra Popovics, Elise Schroeder

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12461, p 12461 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22

Fibrogenic and inflammatory processes in the prostate are linked to the development of lower urinary tract symptoms (LUTS) in men. Our previous studies identified that osteopontin (OPN), a pro-fibrotic cytokine, is abundant in the prostate of men wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be36c69dc29a81c5f7ad9d4977bd1d0
https://www.mdpi.com/1422-0067/22/22/12461

A NEW approach for characterizing mouse urinary pathophysiologies

Autor: Teresa T Liu, Douglas W. Strand, Chad M. Vezina, Gervaise H. Henry, Hannah Ruetten, William A. Ricke, Heidi Spratt

Publikováno v: Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Physiological Reports

The void spot assay (VSA) is a cost‐effective method for evaluating and quantifying mouse urinary voiding phenotypes. The VSA has been used to differentiate voiding behaviors between experimental groups, but not as a diagnostic assay. To build towa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69af7b0d63b138e0dae46794e9b9c736
https://doaj.org/article/ae7c8d68f8b24d78844ccb6edd3fb848

Insight and Resources From a Study of the 'Impact of Sex, Androgens, and Prostate Size on C57BL/6J Mouse Urinary Physiology

Autor: Kyle A Wegner, Richard E. Peterson, Helen L Zhang, Paul C. Marker, Jill A. Macoska, Simran K. Sandhu, Zunyi Wang, Chad M. Vezina, Dale E. Bjorling, Hannah Ruetten, William A. Ricke, Jaskiran K Sandhu, Peiqing Wang, Brett Mueller, Jacquelyn Morkrid

Publikováno v: Toxicol Pathol

The purpose of this symposium report is to summarize information from a session 3 oral presentation at the Society of Toxicologic Pathology Annual Symposium in Raleigh, North Carolina. Mice are genetically tractable and are likely to play an importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee903d49c630c6be2d25876c3e4345ec
https://doi.org/10.1177/0192623319877867