Examining the Effectiveness of Social Media for the Dissemination of Research Evidence for Health and Social Care Practitioners: Systematic Review and Meta-Analysis

Autor: Sarah Roberts-Lewis, Helen Baxter, Gill Mein, Sophia Quirke-McFarlane, Fiona J Leggat, Hannah Garner, Martha Powell, Sarah White, Lindsay Bearne

Publikováno v: Journal of Medical Internet Research, Vol 26, p e51418 (2024)

BackgroundSocial media use has potential to facilitate the rapid dissemination of research evidence to busy health and social care practitioners. ObjectiveThis study aims to quantitatively synthesize evidence of the between- and within-group effecti

Externí odkaz: https://doaj.org/article/3187318239dd4203a4a63534f417e1af

PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer

Autor: Leonie Voorwerk, Olga I. Isaeva, Hugo M. Horlings, Sara Balduzzi, Maksim Chelushkin, Noor A. M. Bakker, Elisa Champanhet, Hannah Garner, Karolina Sikorska, Claudette E. Loo, Inge Kemper, Ingrid A. M. Mandjes, Michiel de Maaker, Jasper J. L. van Geel, Jorianne Boers, Maaike de Boer, Roberto Salgado, Marloes G. J. van Dongen, Gabe S. Sonke, Karin E. de Visser, Ton N. Schumacher, Christian U. Blank, Lodewyk F. A. Wessels, Agnes Jager, Vivianne C. G. Tjan-Heijnen, Carolien P. Schröder, Sabine C. Linn, Marleen Kok

Publikováno v: Nature Cancer, 4, 535-549. Springer Nature
Nature Cancer, 4(4), 535-549. Nature Research

Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research revealed an immune-related ILC subset, and in mouse ILC models, synergy between immune chec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173e4cc0d70da59f93de91b9372cee78
https://doi.org/10.1038/s43018-023-00542-x

Immune crosstalk in cancer progression and metastatic spread: a complex conversation

Autor: Karin E. de Visser, Hannah Garner

Publikováno v: Nature Reviews Immunology. 20:483-497

Metastatic disease is responsible for approximately 90% of cancer deaths. For successful dissemination and metastasis, cancer cells must evade detection and destruction by the immune system. This process is enabled by factors secreted by the primary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e702ab0cf4724f9c793370b0df563a69
https://doi.org/10.1038/s41577-019-0271-z

IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

Autor: Olga S. Blomberg, Lorenzo Spagnuolo, Hannah Garner, Leonie Voorwerk, Olga I. Isaeva, Ewald van Dyk, Noor Bakker, Myriam Chalabi, Chris Klaver, Maxime Duijst, Kelly Kersten, Marieke Brüggemann, Dorien Pastoors, Cheei-Sing Hau, Kim Vrijland, Elisabeth A.M. Raeven, Daphne Kaldenbach, Kevin Kos, Inna S. Afonina, Paulien Kaptein, Louisa Hoes, Willemijn S.M.E. Theelen, Paul Baas, Emile E. Voest, Rudi Beyaert, Daniela S. Thommen, Lodewyk F.A. Wessels, Karin E. de Visser, Marleen Kok

Publikováno v: CANCER CELL

Immune checkpoint blockade (ICB) has heralded a new era in cancer therapy. Research into the mechanisms underlying response to ICB has predominantly focused on T cells; however, effective immune responses require tightly regulated crosstalk between i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad37e511061ec36826986b3010056ea
https://doi.org/10.1016/j.ccell.2022.11.014

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

Autor: Ana-Maria Lennon-Duménil, Enrique Gutiérrez-Martinez, Stéphanie Hugues, Grégoire Lauvau, Hannah Garner, Jakob Loschko, Emmanuel L. Gautier, Rachel Golub, Jake Y. Henry, Elisa Gomez-Perdiguero, Shinelle Menezes, Frederic Geissmann, M. Paula Longhi, Daisy Melandri, Christian E. Jacome-Galarza, Alain Bessis, Pierre Guermonprez, Thibaut Perchet, Giorgio Anselmi, Juan Dubrot, Sergio A. Quezada, Rajen Patel, Michel C. Nussenzweig

Publikováno v: Immunity
Immunity, Elsevier, 2016, 45 (6), pp.1205-1218. ⟨10.1016/j.immuni.2016.12.001⟩
Immunity, Vol. 45, No 6 (2016) pp. 1205-1218
Immunity, 2016, 45 (6), pp.1205-1218. ⟨10.1016/j.immuni.2016.12.001⟩
Menezes, S, Melandri, D, Anselmi, G, Perchet, T, Loschko, J, Dubrot, J, Patel, R, Gautier, E L, Hugues, S, Longhi, M P, Henry, J Y, Quezada, S A, Lauvau, G, Lennon-Duménil, A M, Gutiérrez-Martínez, E, Bessis, A, Gomez-Perdiguero, E, Jacome-Galarza, C E, Garner, H, Geissmann, F, Golub, R, Nussenzweig, M C & Guermonprez, P 2016, ' The Heterogeneity of Ly6C hi Monocytes Controls Their Differentiation into iNOS + Macrophages or Monocyte-Derived Dendritic Cells ', Immunity, vol. 45, no. 6, pp. 1205-1218 . https://doi.org/10.1016/j.immuni.2016.12.001

Summary Inflammation triggers the differentiation of Ly6Chi monocytes into microbicidal macrophages or monocyte-derived dendritic cells (moDCs). Yet, it is unclear whether environmental inflammatory cues control the polarization of monocytes toward e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f172401d5e17f7ff95af1d145a65b2
https://doi.org/10.1016/j.immuni.2016.12.001