Zobrazeno 1 - 10
of 880
pro vyhledávání: '"Hannah, Carter"'
Autor:
Caroline S. Jansen, Meghana S. Pagadala, Maria A. Cardenas, Roshan S. Prabhu, Subir Goyal, Chengjing Zhou, Prasanthi Chappa, BaoHan T. Vo, Chengyu Ye, Benjamin Hopkins, Jim Zhong, Adam Klie, Taylor Daniels, Maedot Admassu, India Green, Neil T. Pfister, Stewart G. Neill, Jeffrey M. Switchenko, Nataliya Prokhnevska, Kimberly B. Hoang, Mylin A. Torres, Suzanna Logan, Jeffrey J. Olson, Edjah K. Nduom, Luke del Balzo, Kirtesh Patel, Stuart H. Burri, Anthony L. Asher, Scott Wilkinson, Ross Lake, Aparna H. Kesarwala, Kristin A. Higgins, Pretesh Patel, Vishal Dhere, Adam G. Sowalsky, Hannah Carter, Mohammad K. Khan, Haydn Kissick, Zachary S. Buchwald
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Enhancing the efficacy of immunotherapy in brain metastases (BrM) requires an improved understanding of the immune composition of BrM and how this is affected by radiation and dexamethasone. Our two-arm pilot study (NCT04895592) allocated 26
Externí odkaz:
https://doaj.org/article/f2e15d60d8c7479ea6d0d2f87a5326a2
Autor:
Zephanie Tyack, Steven McPhail, Gregory A. Aarons, Kelly McGrath, Andrew Barron, Hannah Carter, Sarah Larkins, Adrian Barnett, Eloise Hummell, Ruth Tulleners, Olivia Fisher, Gillian Harvey, Lee Jones, Kate Murray, Bridget Abell
Publikováno v:
Implementation Science, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background A dramatic decline in mental health of people worldwide in the early COVID-19 pandemic years has not recovered. In rural and remote Australia, access to appropriate and timely mental health services has been identified as a major
Externí odkaz:
https://doaj.org/article/5a5b58709cfa4c23bf05ed626d9e45af
Publikováno v:
BMJ Open, Vol 14, Iss 11 (2024)
Objective To investigate associations between the availability and timing of digitally available advance care planning (ACP) documents and hospital use and costs during the last 6 months of life.Design Retrospective population-based cohort study usin
Externí odkaz:
https://doaj.org/article/ca6ad4aa95464de5aecd0c500c4a038c
Autor:
Juan Carlos Jado, Michelle Dow, Krypton Carolino, Adam Klie, Gregory J. Fonseca, Trey Ideker, Hannah Carter, Elizabeth A. Winzeler
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract In vitro evolution and whole genome analysis has proven to be a powerful method for studying the mechanism of action of small molecules in many haploid microbes but has generally not been applied to human cell lines in part because their dip
Externí odkaz:
https://doaj.org/article/393b41621ea749ec915b0726a2c71095
Autor:
Clarence K. Mah, Noorsher Ahmed, Nicole A. Lopez, Dylan C. Lam, Avery Pong, Alexander Monell, Colin Kern, Yuanyuan Han, Gino Prasad, Anthony J. Cesnik, Emma Lundberg, Quan Zhu, Hannah Carter, Gene W. Yeo
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract The spatial organization of molecules in a cell is essential for their functions. While current methods focus on discerning tissue architecture, cell–cell interactions, and spatial expression patterns, they are limited to the multicellular
Externí odkaz:
https://doaj.org/article/370b90adee9c46aa93c11ebcecb1cb61
Autor:
Kivilcim Ozturk, Rebecca Panwala, Jeanna Sheen, Kyle Ford, Nathan Jayne, Andrew Portell, Dong-Er Zhang, Stephan Hutter, Torsten Haferlach, Trey Ideker, Prashant Mali, Hannah Carter
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114436- (2024)
Summary: Single-gene missense mutations remain challenging to interpret. Here, we deploy scalable functional screening by sequencing (SEUSS), a Perturb-seq method, to generate mutations at protein interfaces of RUNX1 and quantify their effect on acti
Externí odkaz:
https://doaj.org/article/7f27471aa05f450da7a0b6c86bd752a9
Autor:
Sameera Senanayake, Zephanie Tyack, Michelle Allen, Steven M McPhail, Bridget Abell, Hannah Carter, Kym Warhurst, Sundresan Naicker
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objectives This scoping review mapped and synthesised original research that identified low-value care in hospital settings as part of multicomponent processes.Design Scoping review.Data sources Electronic databases (EMBASE, PubMed, CINAHL, PsycINFO
Externí odkaz:
https://doaj.org/article/030f0ccdae2b447ca5f0a5b61d24224a
Autor:
Joseph Bendik, Sandhya Kalavacherla, Nicholas Webster, Joseph Califano, Elana J. Fertig, Michael F. Ochs, Hannah Carter, Theresa Guo
Publikováno v:
BioMedInformatics, Vol 3, Iss 4, Pp 853-868 (2023)
Protein variation that occurs during alternative splicing has been shown to play a major role in disease onset and oncogenesis. Due to this, we have developed OutSplice, a user-friendly algorithm to classify splicing outliers in tumor samples compare
Externí odkaz:
https://doaj.org/article/16188fc4483c4eaaacb080fca45cf735
Autor:
Andrea Castro, Aaron M. Goodman, Zachary Rane, James V. Talwar, Garrett M. Frampton, Gerald P. Morris, Scott M. Lippman, Xinlian Zhang, Razelle Kurzrock, Hannah Carter
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 6, Iss 3, Pp 127-132 (2023)
Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can cure patients with high-risk myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). However, many patients relapse or develop debilitating graft-versus-host d
Externí odkaz:
https://doaj.org/article/22c436f30661436c9790d520e9a602ed
Autor:
Michael J. Dennis, Sophia Bylsma, Lisa Madlensky, Meghana S. Pagadala, Hannah Carter, Sandip P. Patel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundImpaired DNA damage response (DDR) can affect immune checkpoint inhibitors (ICI) efficacy and lead to heightened immune activation. We assessed the impact of pathogenic or likely pathogenic (P/LP) germline DDR mutations on ICI response and
Externí odkaz:
https://doaj.org/article/1e0413811b3145389253abec7216b286