Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hanna-Riikka Heinonen"'
Autor:
Hanna-Riikka Heinonen, Annukka Pasanen, Oskari Heikinheimo, Tomas Tanskanen, Kimmo Palin, Jaana Tolvanen, Pia Vahteristo, Jari Sjöberg, Esa Pitkänen, Ralf Bützow, Netta Mäkinen, Lauri A. Aaltonen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus. Prior st
Externí odkaz:
https://doaj.org/article/15a7fd008b7b42a49d3e827b391c4772
Autor:
Niko Välimäki, Heli Kuisma, Annukka Pasanen, Oskari Heikinheimo, Jari Sjöberg, Ralf Bützow, Nanna Sarvilinna, Hanna-Riikka Heinonen, Jaana Tolvanen, Simona Bramante, Tomas Tanskanen, Juha Auvinen, Outi Uimari, Amjad Alkodsi, Rainer Lehtonen, Eevi Kaasinen, Kimmo Palin, Lauri A Aaltonen
Publikováno v:
eLife, Vol 7 (2018)
Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic risk in six cohorts. Effects of the
Externí odkaz:
https://doaj.org/article/94e199383a454da09e3a65af3810b73f
Publikováno v:
Cardiovascular Pathology. 30:1-5
A male patient with obstructive jaundice was found to have an incidental nodule within the inferior vena cava (IVC), below the level of the renal vein, on abdominal imaging. At the time of the Whipple's procedure for pancreatic adenocarcinoma, the IV
Autor:
Nanna Sarvilinna, Lauri A. Aaltonen, Jaana Tolvanen, Hanna-Riikka Heinonen, Norma Frizzell, Anne Ahtikoski, Pia Vahteristo, Ralf Bützow, Miika Mehine, Outi Uimari, Esa Pitkänen, Netta Mäkinen, Salla Välipakka, Tuomas Heikkinen, Jari Sjöberg, Kati Kämpjärvi
Publikováno v:
British Journal of Cancer
Background: Uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer (HLRCC) patients are driven by fumarate hydratase (FH) inactivation or occasionally by mediator complex subunit 12 (MED12) mutations. The aim of this study was to ana
Autor:
Esa Pitkänen, Jari Sjöberg, Kati Kämpjärvi, Anna Vähärautio, Pia Vahteristo, Miika Mehine, Oskari Heikinheimo, Eevi Kaasinen, Annukka Pasanen, Nanna Sarvilinna, Ralf Bützow, Hanna-Riikka Heinonen, Netta Mäkinen, Mervi Aavikko, Lauri A. Aaltonen
Publikováno v:
Proceedings of the National Academy of Sciences. 113:1315-1320
Uterine leiomyomas are common benign smooth muscle tumors that impose a major burden on women's health. Recent sequencing studies have revealed recurrent and mutually exclusive mutations in leiomyomas, suggesting the involvement of molecularly distin
Autor:
Kimmo Palin, Amjad Alkodsi, Rainer Lehtonen, Tomas Tanskanen, Nanna Sarvilinna, Niko Välimäki, Annukka Pasanen, Jaana Tolvanen, Hanna-Riikka Heinonen, Eevi Kaasinen, Juha Auvinen, Heli Kuisma, Jari Sjöberg, Lauri A. Aaltonen, Ralf Bützow, Outi Uimari, Simona Bramante, Oskari Heikinheimo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a821bde24d3a0979c9db9f29fa89b0f
https://doi.org/10.7554/elife.37110.047
https://doi.org/10.7554/elife.37110.047
Autor:
Oskari Heikinheimo, Kimmo Palin, Jaana Tolvanen, Rainer Lehtonen, Amjad Alkodsi, Simona Bramante, Jari Sjöberg, Annukka Pasanen, Tomas Tanskanen, Niko Välimäki, Eevi Kaasinen, Heli Kuisma, Terhi Piltonen, Lauri A. Aaltonen, Nanna Sarvilinna, Hanna-Riikka Heinonen, Ralf Bützow, Juha Auvinen
Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 5,417 UL cases and 331,791 controls was performed, followed by replication of the genomic risk in two cohorts. Effects of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5526d50fe01566a13fca9dbc6fc6e1
Autor:
Hanna-Riikka Heinonen, Heli Kuisma, Ralf Bützow, Oskari Heikinheimo, Jari Sjöberg, Simona Bramante, Outi Uimari, Juha Auvinen, Niko Välimäki, Annukka Pasanen, Nanna Sarvilinna, Jaana Tolvanen, Lauri A. Aaltonen, Rainer Lehtonen, Tomas Tanskanen, Kimmo Palin, Amjad Alkodsi, Eevi Kaasinen
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic risk in six cohorts. Effects of the
Autor:
Netta Mäkinen, Ralf Bützow, Annukka Pasanen, Nanna Sarvilinna, Jari Sjöberg, Hanna-Riikka Heinonen, Auli Karhu, Miika Mehine, Oskari Heikinheimo, Eevi Kaasinen, Lauri A. Aaltonen, Esa Pitkänen
Publikováno v:
British Journal of Cancer
Background: Uterine leiomyomas can be classified into molecularly distinct subtypes according to their genetic triggers: MED12 mutations, HMGA2 upregulation, or inactivation of FH. The aim of this study was to identify metabolites and metabolic pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd46322bc5c56633f4c70131476f7203
http://hdl.handle.net/10138/303770
http://hdl.handle.net/10138/303770
Autor:
Jaana Tolvanen, Lauri A. Aaltonen, Ralf Bützow, Jari Sjöberg, Hanna-Riikka Heinonen, Pia Vahteristo, Annukka Pasanen, Netta Mäkinen, Esa Pitkänen, Kimmo Palin, Oskari Heikinheimo, Tomas Tanskanen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus. Prior studies, wi