Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hanna Sundstrom"'
Autor:
Naja Nyffenegger, Anna Flace, Ahmet Varol, Patrick Altermatt, Cédric Doucerain, Hanna Sundstrom, Franz Dürrenberger, Vania Manolova
Publikováno v:
HemaSphere, Vol 8, Iss 9, Pp n/a-n/a (2024)
Abstract Hemochromatosis is an inherited iron overload condition caused by mutations that reduce the levels of the iron‐regulatory hormone hepcidin or its binding to ferroportin. The hepcidin–ferroportin axis is pivotal to iron homeostasis, provi
Externí odkaz:
https://doaj.org/article/6275d404ed394da882c80dfa9aa97074
Autor:
Elena Farah Lehmann, Márton Liziczai, Katarzyna Drożdżyk, Patrick Altermatt, Cassiano Langini, Vania Manolova, Hanna Sundstrom, Franz Dürrenberger, Raimund Dutzler, Cristina Manatschal
Publikováno v:
eLife, Vol 12 (2023)
A central regulatory mechanism of iron homeostasis in humans involves ferroportin (FPN), the sole cellular iron exporter, and the peptide hormone hepcidin, which inhibits Fe2+ transport and induces internalization and degradation of FPN. Dysregulatio
Externí odkaz:
https://doaj.org/article/4ac4fcae60224999b4e642c1a73380b2
Autor:
Márton Liziczai, Elena Farah Lehmann, Katarzyna Drożdżyk, Patrick Altermatt, Cassiano Langini, Vania Manolova, Hanna Sundstrom, Franz Dürrenberger, Raimund Dutzler, Cristina Manatschal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33375ae93130ea3d5ea3085accb79044
https://doi.org/10.7554/elife.83053.sa2
https://doi.org/10.7554/elife.83053.sa2
Autor:
Elena F. Lehmann, Márton Liziczai, Katarzyna Drożdżyk, Patrick Altermatt, Vania Manolova, Hanna Sundstrom, Franz Dürrenberger, Raimund Dutzler, Cristina Manatschal
A central regulatory mechanism of iron homeostasis in humans involves ferroportin (FPN), the sole cellular iron exporter, and the peptide hormone hepcidin, which inhibits Fe2+ transport and induces internalization and degradation of FPN. Dysregulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db407b6a8ae6923b2865dde06cef1894
https://doi.org/10.1101/2022.08.29.505642
https://doi.org/10.1101/2022.08.29.505642
Autor:
Michael Walch, Hanna Sundstrom, Claudia Dumrese, Maries van den Broek, Silvana K. Rampini, Peter Sander, Joseph Marino, Daniel L. Glauser, Peter Groscurth, Sonja Latinovic-Golic, Isabelle Stoeckli, Urs Ziegler, Alexander Vogetseder
Publikováno v:
JOURNAL OF IMMUNOLOGY
Regulation of cytotoxic effector molecule expression in human CTLs after viral or bacterial activation is poorly understood. By using human autologous dendritic cells (DCs) to prime T lymphocytes, we found perforin only highly up-regulated in virus-
Autor:
Ana Velic, Urs Ziegler, Peter Groscurth, Hanna Sundstrom, Michael Walch, Sonja Latinovic-Golic, Claudia Dumrese, Carsten A. Wagner
Publikováno v:
BMC Immunology, Vol 8, Iss 1, p 14 (2007)
BMC Immunology
BMC Immunology
Background Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells play an essential role in the host defence against intracellular pathogens such as Listeria, and Mycobacteria. The key mediator of bacteria-directed cytotoxicity is granulysin, a
Autor:
Vojtech Dvorak, Tabea Wiedmer, Alvaro Ingles-Prieto, Patrick Altermatt, Helena Batoulis, Felix Bärenz, Eckhard Bender, Daniela Digles, Franz Dürrenberger, Laura H. Heitman, Adriaan P. IJzerman, Douglas B. Kell, Stefanie Kickinger, Daniel Körzö, Philipp Leippe, Thomas Licher, Vania Manolova, Riccardo Rizzetto, Francesca Sassone, Lia Scarabottolo, Avner Schlessinger, Vanessa Schneider, Hubert J. Sijben, Anna-Lena Steck, Hanna Sundström, Sara Tremolada, Maria Wilhelm, Marina Wright Muelas, Diana Zindel, Claire M. Steppan, Giulio Superti-Furga
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The solute carrier (SLC) superfamily represents the biggest family of transporters with important roles in health and disease. Despite being attractive and druggable targets, the majority of SLCs remains understudied. One major hurdle in research on
Externí odkaz:
https://doaj.org/article/57add1b341ee425fb3b53addb4c3b962
Autor:
Sonja Latinovic-Golic, Michael Walch, Peter Groscurth, Hanna Sundstrom, Claudia Dumrese, Urs Ziegler
Publikováno v:
BMC Immunology
BMC Immunology, Vol 8, Iss 1, p 9 (2007)
BMC Immunology, Vol 8, Iss 1, p 9 (2007)
BackgroundGranulysin, a cytotoxic protein expressed in human natural killer cells and activated T lymphocytes, exhibits cytolytic activity against a variety of intracellular microbes. Expression and transcription have been partially characterised in