Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Hanna Siiskonen"'
Publikováno v:
Tobacco Induced Diseases, Vol 22, Iss May, Pp 1-13 (2024)
Introduction The relationship between tobacco smoking and cutaneous photodamage or malignancies is still unclear. In addition to smoking, both ultraviolet radiation and immunosuppression have an impact on carcinogenesis. The purpose was to study the
Externí odkaz:
https://doaj.org/article/f43bbed2333440318b5915ab8c6405ea
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Patients at risk of skin cancers can develop varying types of cutaneous malignancies. However, some subjects may develop only one type of lesion. In this cross-sectional study, the spectrum of premalignant (PM) and malignant skin lesions and
Externí odkaz:
https://doaj.org/article/9ef5656ddcc34747afe82974b5ab2f55
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractPurpose: Mast cells, their serine proteinase tryptase, and immunoglobulin E (IgE) can be involved in cutaneous carcinogenesis.Materials and methods: To study the association of tryptase+ and IgE+ cells with photodamage and skin cancers 385 ad
Externí odkaz:
https://doaj.org/article/96cf5246c4a447ee8aba8e865a675776
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background A regional skin cancer prevention program in Eastern Finland revealed a relatively high age-standardized mortality due to malignant melanoma during 2013–2017. An explanation for this is needed. Purpose To analyse the 543 melanom
Externí odkaz:
https://doaj.org/article/1e2df13a5c774139b3e7c7fe16be3806
Autor:
Satu Salmi, Anton Lin, Benjamin Hirschovits-Gerz, Mari Valkonen, Niina Aaltonen, Reijo Sironen, Hanna Siiskonen, Sanna Pasonen-Seppänen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background FoxP3+ Regulatory T cells (Tregs) and indoleamine-2,3-dioxygenase (IDO) participate in the formation of an immunosuppressive tumor microenvironment (TME) in malignant cutaneous melanoma (CM). Recent studies have reported that IDO
Externí odkaz:
https://doaj.org/article/12a1a2380c7d4d99bf4a09645778dce1
Publikováno v:
Analytical Cellular Pathology, Vol 2022 (2022)
Mast cells contribute to the pathogenesis of cutaneous vasculitis through complement C3 that is cleaved to C3b and then to iC3b by complement factor I. The receptor of iC3b, CD11b, is expressed on neutrophils and monocytes and CD14 on monocytes. Thei
Externí odkaz:
https://doaj.org/article/bb06cc8e05794d9d8adf8a2600ea121f
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
The incidence of cutaneous melanoma is rapidly increasing worldwide. Cutaneous melanoma is an aggressive type of skin cancer, which originates from malignant transformation of pigment producing melanocytes. The main risk factor for melanoma is ultrav
Externí odkaz:
https://doaj.org/article/20706058523b4005952b7ac489df1b21
Autor:
Satu Salmi, Kaisla Hälinen, Anton Lin, Sanna Suikkanen, Otto Jokelainen, Eija Rahunen, Hanna Siiskonen, Sanna Pasonen-Seppänen
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3209 (2022)
The immunosuppressive tumor microenvironment (TME) consists of suppressive cells producing a variety of immunomodulatory proteins, such as programmed death ligand 1 (PD-L1) and indoleamine-2,3-dioxygenase (IDO). Although granzyme B (GrB) is known to
Externí odkaz:
https://doaj.org/article/c980d7ff2553458faae068a3b0ec6a38
Autor:
Hanna Siiskonen, Ilkka Harvima
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The intimate interaction between mast cells and sensory nerves can be illustrated by the wheal and surrounding flare in an urticarial reaction in human skin. This reaction is typically associated with an intense itch at the reaction site. Upon activa
Externí odkaz:
https://doaj.org/article/bdf349573a8d42288bc3cef7ed944498
Autor:
Jenni Komulainen, Hanna Siiskonen, Salla Haimakainen, Emilia Kanasuo, Rauno J. Harvima, Ilkka T. Harvima
Publikováno v:
Melanoma Research. 33:218-229