Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hanna Shevalye"'
Autor:
Sanjib Saha, Jessica M. Skeie, Gregory A. Schmidt, Tim Eggleston, Hanna Shevalye, Christopher S. Sales, Pornpoj Phruttiwanichakun, Apurva Dusane, Matthew G. Field, Tommy A. Rinkoski, Michael P. Fautsch, Keith H. Baratz, Madhuparna Roy, Albert S. Jun, Chandler Pendleton, Aliasger K. Salem, Mark A. Greiner
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103348- (2024)
Fuchs endothelial corneal dystrophy (FECD), the leading indication for corneal transplantation in the U.S., causes loss of corneal endothelial cells (CECs) and corneal edema leading to vision loss. FECD pathogenesis is linked to impaired response to
Externí odkaz:
https://doaj.org/article/a5950d340bbe43c3be514fa204657879
Autor:
Brian D. Fink, Liping Yu, Lawrence Coppey, Alexander Obrosov, Hanna Shevalye, Robert J. Kerns, Mark A. Yorek, William I. Sivitz
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Abstract Previous work by ourselves and others showed that mitoquinone (mitoQ) reduced oxidative damage and prevented hepatic fat accumulation in mice made obese with high‐fat (HF) feeding. Here we extended these studies to examine the effect of mi
Externí odkaz:
https://doaj.org/article/74e0aaac2f314a59b44deb47e3e8edbc
Autor:
Lawrence Coppey, Alexander Obrosov, Hanna Shevalye, Eric Davidson, William Paradee, Mark A. Yorek
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
To rigorously explore the role of omega-3 polyunsaturated fatty acids (PUFA) in the treatment of diabetic peripheral neuropathy (DPN), we have created a transgenic mouse utilizing a Cre-lox promoter to control overexpression of human 15-lipoxygenase-
Externí odkaz:
https://doaj.org/article/9d6be9e61c6f4010baf31e6f63688de3
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Aims. Determine the effect of dietary oils enriched in different mono- or polyunsaturated fatty acids, i.e., olive oil (18 : 1, oleic acid), safflower oil (18 : 2 n-6, linoleic acid), flaxseed oil (18 : 3 n-3, alpha linolenic acid), evening primrose
Externí odkaz:
https://doaj.org/article/b47fa2904ac342d19a226963e92d094c
Publikováno v:
Journal of Diabetes Research, Vol 2018 (2018)
In this study, we wanted to extend our investigation of the efficacy of fish oil with or without salsalate on vascular and neural complications using a type 2 diabetic rat model. Four weeks after the onset of hyperglycemia, diabetic rats were treated
Externí odkaz:
https://doaj.org/article/7d5ed42bd3cf4cc18a18194093b192eb
Autor:
Matthew S. Yorek, Lawrence J. Coppey, Hanna Shevalye, Alexander Obrosov, Randy H. Kardon, Mark A. Yorek
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2016 (2016)
Aims. In this study a streptozotocin induced type 1 diabetes mouse model was used to assess the effectiveness of salsalate, menhaden oil, the combination of salsalate and menhaden oil, or resolvin D1 on neuropathic endpoints. Materials and Methods. C
Externí odkaz:
https://doaj.org/article/4fc28f0ebb4f4cca9690fc92f5d9429c
Autor:
Brian C. Leonard, Sangwan Park, Soohyun Kim, Laura J. Young, Iman Jalilian, Krista Cosert, Xunzhi Zhang, Jessica M. Skeie, Hanna Shevalye, Nayeli Echeverria, Vanessa Rozo, Xin Gong, Chao Xing, Christopher J. Murphy, Mark A. Greiner, V. Vinod Mootha, Vijay Krishna Raghunathan, Sara M. Thomasy
Publikováno v:
Investigative ophthalmology & visual science, vol 64, iss 4
PurposeWe sought to define the role of Wwtr1 in murine ocular structure and function and determine the role of mechanotransduction in Fuchs' endothelial corneal dystrophy (FECD), with emphasis on interactions between corneal endothelial cells (CEnCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556f460b3e3a6c3eb64d4dd746dac501
https://escholarship.org/uc/item/2hr2q66c
https://escholarship.org/uc/item/2hr2q66c
Autor:
Sanjib Saha, Jessica M. Skeie, Gregory A. Schmidt, Tim Eggleston, Hanna Shevalye, Christopher S. Sales, Pornpoj Phruttiwanichakun, Matthew Field, Tommy A. Rinkoski, Michael P. Fautsch, Keith H. Baratz, Madhuparna Roy, Albert S. Jun, Aliasger K. Salem, Mark A. Greiner
Fuchs endothelial corneal dystrophy (FECD), a progressive polygenic disease that causes degeneration of the corneal endothelium, is the leading indication for corneal transplantation in the U.S. Characteristically, loss of corneal endothelial cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884c3b3883abf31a44f955254d4dce2e
https://doi.org/10.1101/2022.06.27.497862
https://doi.org/10.1101/2022.06.27.497862
Autor:
Mark A. Yorek, Brian D. Fink, Robert J. Kerns, Liping Yu, Alexander Obrosov, William I. Sivitz, Hanna Shevalye, Lawrence J. Coppey
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Previous work by ourselves and others showed that mitoquinone (mitoQ) reduced oxidative damage and prevented hepatic fat accumulation in mice made obese with high‐fat (HF) feeding. Here we extended these studies to examine the effect of mitoQ on pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81dfef801dd55d3f8c56fdfa54c0574
https://doi.org/10.1002/prp2.701
https://doi.org/10.1002/prp2.701
Autor:
Lawrence J. Coppey, Alexander Obrosov, Eric P. Davidson, Mark A. Yorek, William I. Sivitz, Pratik Rajesh Chheda, Hanna Shevalye, Robert J. Kerns, Brian D. Fink
Publikováno v:
Free Radic Res
This study sought to determine whether the addition of mitoquinone (Mito-Q) in the diet is an effective treatment for peripheral neuropathy in animal models of diet-induced obesity (pre-diabetes) and type 2 diabetes. Unlike other anti-oxidative stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7425c5cec4fd2fcaba807ffc85b3fc1
https://europepmc.org/articles/PMC7329571/
https://europepmc.org/articles/PMC7329571/