Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hanna Schotola"'
Autor:
Ashham Mansur, Maximilian Steinau, Aron Frederik Popov, Sinisa Milenovic, Christian Bireta, Alexander Weymann, Hanna Schotola, Christoph H Wiese, Tim Beissbarth, Mladen Tzvetkov, José Hinz
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131155 (2015)
Genetic variants within the endothelin-1 gene (EDN1) have been associated with several cardiovascular diseases and may act as genetic prognostic markers. Here, we explored the overall relevance of EDN1 polymorphisms for long-term survival in patients
Externí odkaz:
https://doaj.org/article/24307e114815412980fd140a8a02f5a0
Publikováno v:
Anaesthesia and intensive care. 45(1)
Acute kidney injury (AKI) is frequently observed after cardiac surgery (CS) with cardiopulmonary bypass (CPB). Multiple mechanisms underlie this phenomenon, including CPB-dependent haemolysis. Haemoglobin is released during haemolysis, and free haemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a126b07e59a7db03a5f23c3a547b25
https://pubmed.ncbi.nlm.nih.gov/28072936
https://pubmed.ncbi.nlm.nih.gov/28072936
Autor:
Ingo Bergmann, A. J. Wetz, Aron-Frederik Popov, Anselm Bräuer, Friedrich A. Schöndube, M. Bauer, B.C. Danner, Hanna Schotola
Publikováno v:
Anaesthesia and intensive care. 44(5)
At the end of cardiopulmonary bypass, there are invariably several hundred millilitres of residual pump blood in the reservoir, which can either be re-transfused or discarded. The objective of this prospective observational study was to investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd03464c9cfef97039815cfd24c1c0f6
https://pubmed.ncbi.nlm.nih.gov/27608341
https://pubmed.ncbi.nlm.nih.gov/27608341
Autor:
Nico Hartmann, Norbert Frey, Gerd Hasenfuss, Jonas Herting, Felix Schatter, Thomas H. Fischer, Steffen Pabel, Samuel Sossalla, Lars S. Maier, Hanna Schotola, Bernhard C. Danner, Jan Gummert, André Renner
Publikováno v:
Heart rhythm. 14(3)
Background Cardiac type 2 ryanodine receptors (RyR2s) play a pivotal role in cellular electrophysiology and contractility. Increased RyR2-mediated diastolic sarcoplasmic reticulum (SR) Ca2+ release is linked to heart failure (HF) and arrhythmias. Dan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06236a8d34f720f45cdc8073fffd40f
https://pubmed.ncbi.nlm.nih.gov/27725286
https://pubmed.ncbi.nlm.nih.gov/27725286
The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology
Autor:
Norbert Frey, Dobromir Dobrev, Nico Hartmann, Inga Braun, Fleur E. Mason, Samuel Sossalla, Steffen Pabel, Thomas H. Fischer, Luiz Belardinelli, Bernhard C. Danner, Gerd Hasenfuss, André Renner, Lars S. Maier, Hanna Schotola, Niels Voigt, Jan Gummert
Introduction Pharmacological rhythm control of atrial fibrillation (AF) in patients with structural heart disease is limited. Ranolazine in combination with low dose dronedarone remarkably reduced AF-burden in the phase II HARMONY trial. We thus aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b375312cb3cb8891a3187fa01497384
https://www.ncbi.nlm.nih.gov/pubmed/27056421
https://www.ncbi.nlm.nih.gov/pubmed/27056421
Autor:
Ralph Knöll, Stefanie Klede, Hanna Schotola, Claudius Jacobshagen, Ali El-Armouche, Wolfgang A. Linke, Kaomei Guan, Tim Seidler, Bernhard Unsöld, Gerd Hasenfuss, Harald Kögler, Julius Emons, Samuel Sossalla
Publikováno v:
European Journal of Heart Failure. 14:430-437
Aims Muscle LIM protein (MLP) null mice are often used as a model for human dilated cardiomyopathy. So far, little is known about the time course and pathomechanisms leading to the development of the adult phenotype. Methods and results We systematic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2407e5f4ddbc639083c0af3a3a1469
https://doi.org/10.1093/eurjhf/hfs020
https://doi.org/10.1093/eurjhf/hfs020
Autor:
Hanna Schotola, Michael Quintel, Taufiek Konrad Rajab, Martin Bauer, Karl Toischer, Samuel Sossalla, Jan D. Schmitto
Publikováno v:
Artificial Organs. 35:1065-1074
The postoperative course after major surgical procedures such as cardiothoracic operations is often accompanied by acute metabolic abnormalities due to large volume and temperature shifts. In general, those intervention-induced trauma might cause the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32016ebf46cd14465ec1d89c1a88a3fd
https://doi.org/10.1111/j.1525-1594.2011.01390.x
https://doi.org/10.1111/j.1525-1594.2011.01390.x
Autor:
Samuel Sossalla, Jan D. Schmitto, Aron F Popov, Julia Schuenemann, Christian Sohns, Suyog A. Mokashi, Florian Heidrich, José Hinz, Kasim O. Coskun, Martin Bauer, Hanna Schotola, Martin Friedrich, Dirk von Lewinski
Publikováno v:
Current Cardiology Reviews
Adenosine monophosphate – activated kinase (AMPK) plays a key role in the coordination of the hearts anabolic and catabolic pathways. It induces a cellular cascade at the center of maintaining energy homeostasis in the cardiomyocytes.. The activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaa941d779779bdfca44f132cecf385
https://doi.org/10.2174/157340310793566073
https://doi.org/10.2174/157340310793566073
Autor:
Philipp Ortmann, Jan D. Schmitto, Michael Quintel, Christian Sohns, Samuel Sossalla, Tobias Vorkamp, Kasim O. Coskun, Martin Bauer, Hanna Schotola, Aron F Popov, Friedrich A. Schöndube, Florian Heidrich, José Hinz, Martin Friedrich, Taufiek Konrad Rajab
Publikováno v:
Artificial Organs. 34:969-979
We established a stable and reproducible animal model of chronic heart failure (CHF) in sheep to investi- gate biomolecular changes. Therefore, two biomarkers, adenosine monophosphate-activated protein kinase (AMPK) and vascular endothelial growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89335db0a586c7c317352cd25d01c96a
https://doi.org/10.1111/j.1525-1594.2010.01121.x
https://doi.org/10.1111/j.1525-1594.2010.01121.x
Autor:
Samuel Sossalla, Lars S. Maier, Hanna Schotola, Katharina Ort, Stefan Neef, Jan D. Schmitto, Timo Schulte, André Renner, Ali El-Armouche, Gerd Hasenfuss, Nina Fluschnik, Jan Gummert, Katrin Wittköpper
Publikováno v:
Circulation Research. 107:1150-1161
Rationale: Heart failure (HF) is known to be associated with increased Ca 2+ /calmodulin-dependent protein kinase (CaMK)II expression and activity. There is still controversial discussion about the functional role of CaMKII in HF. Moreover, CaMKII in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e56740019cb2c880477415b2d4410e
https://doi.org/10.1161/circresaha.110.220418
https://doi.org/10.1161/circresaha.110.220418