Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hanna Schierbeck"'
Autor:
Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Ulf Andersson
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Abstract Background Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. HMGB1 is a nuclear protein released extracellularly during proinflammatory lytic cell death or secreted by activated macrophages, N
Externí odkaz:
https://doaj.org/article/a55408e06b2342e3acfc4027a7532cf9
Autor:
Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Daniel J. Antoine, Ulf Andersson
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-2 (2020)
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s10020-020-00263-2
Externí odkaz:
https://doaj.org/article/faf37b5b47294b398ed794f08ce9ef7b
Autor:
Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Daniel J. Antoine, Ulf Andersson
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-1 (2020)
Externí odkaz:
https://doaj.org/article/ec7b06ddb2584af5ab470b51b623fae6
Autor:
Helena Erlandsson Harris, Karin Palmblad, Erik Sundberg, AnnaCarin Horne, Hanna Schierbeck, Ulf Andersson, Jan-Inge Henter
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Molecular Medicine
Molecular Medicine
Background Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. HMGB1 is a nuclear protein released extracellularly during proinflammatory lytic cell death or secreted by activated macrophages, NK cells,
Autor:
Helena Erlandsson Harris, Erik Sundberg, AnnaCarin Horne, Jan-Inge Henter, Ulf Andersson, Daniel J. Antoine, Hanna Schierbeck, Karin Palmblad
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-2 (2020)
Molecular Medicine
Molecular Medicine
Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. High mobility group box 1 (HMGB1) is a nuclear protein extensively leaked extracellularly during necrotic cell death or actively secreted by natural ki
Autor:
Kevin J. Tracey, Melissa Robinson, Kevin Kwan, Helena Erlandsson-Harris, Sangeeta S. Chavan, Hanna Schierbeck, Daniel J. Antoine, Jianhua Li, Heidi Wähämaa, Peter Lundbäck, Ben Lu, Huan Yang, Ulf Andersson, Marieke A. D. van Zoelen, Haichao Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 111:3068-3073
Extracellular high-mobility group box (HMGB)1 mediates inflammation during sterile and infectious injury and contributes importantly to disease pathogenesis. The first critical step in the release of HMGB1 from activated immune cells is mobilization
Autor:
Helena Erlandsson-Harris, Hanna Schierbeck, Karin Palmblad, Ulf Andersson, Peter Lundbäck, Lars Ottosson, Lena Klevenvall
Publikováno v:
Molecular Medicine. 17:1039-1044
High mobility group box chromosomal protein 1 (HMGB1) is a DNA-binding nuclear protein that can be released from dying cells and activated myeloid cells. Extracellularly, HMGB1 promotes inflammation. Experimental studies demonstrate HMGB1 to be a pat
Publikováno v:
Molecular Medicine. 16:343-351
Several HMGB1-specific antagonists have provided beneficial results in multiple models of inflammatory disease-preclinical trials including arthritis. Since no HMGB1-specific targeted therapy has yet reached the clinic, we have performed in vitro stu
Autor:
Iva Gunnarsson, Lina Wirestam, Jonas Wetterö, Hanna Schierbeck, Thomas Skogh, Christopher Sjöwall, Lars Ottosson, Helena Erlandsson-Harris
Publikováno v:
Arthritis Research & Therapy
Introduction: The non-histone nuclear protein high mobility group box protein-1 (HMGB1) is typically associated with nucleosomes, but may shuttle between the nucleus and the cytoplasm, and under some conditions also be released extracellularly and pa
Autor:
Karin Palmblad, Erik Sundberg, Jan-Inge Henter, Ulf Andersson, Hanna Schierbeck, AnnaCarin Horne, Helena Erlandsson Harris, Daniel J. Antoine
Publikováno v:
Molecular medicine (Cambridge, Mass.). 20
Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. High mobility group box 1 (HMGB1) is a nuclear protein extensively leaked extracellularly during necrotic cell death or actively secreted by natural ki