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pro vyhledávání: '"Hanna S. Pereira"'
Autor:
Leila C.A. Cardoso, Jair A. Tenorio Castaño, Hanna S. Pereira, Maria Angélica de F.D. Lima, Anna Cláudia E. dos Santos, Paulo S. de Faria, Sima Ferman, Héctor N. Seuánez, Julián B. Nevado, José Carlos Cabral de Almeida, Pablo Lapunzina, Fernando R. Vargas
Publikováno v:
Genetics and Molecular Biology, Vol 35, Iss 4, Pp 714-724 (2012)
The most frequent epigenetic alterations in Wilms tumor (WT) occur at WT2, assigned to 11p15. WT2 consists of two domains: telomeric domain 1 (DMRH19) that contains the IGF2 gene and an imprinted maternally expressed transcript (H19) and centromeric
Externí odkaz:
https://doaj.org/article/29523dd8ee404367b56262be97ca51b0
Autor:
Hector N. Seuanez, Sheila Coelho Soares Lima, Leila C.A. Cardoso, Paulo Antônio Silvestre de Faria, Hanna S. Pereira
Publikováno v:
Frontiers in Bioscience. 10:143-154
Wilms' tumor (WT) is the most frequent renal cancer in childhood, the occurrence of which is characterized by a relatively low frequency of associated mutations. While epigenetic alterations have been postulated to play a relevant role in the emergen