Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hanna S. Hong"'
Autor:
Nneka E. Mbah, Amy L. Myers, Peter Sajjakulnukit, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Heather Giza, Derek Dang, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zhu, Megan Radyk, Brooke Lavoie, Viveka Nand Yadav, Imhoi Koo, Andrew D. Patterson, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract H3K27M diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), exhibit cellular heterogeneity comprising less-differentiated oligodendrocyte precursors (OPC)-like stem cells and more differentiated astrocyte (AC)-l
Externí odkaz:
https://doaj.org/article/b60128e341cf4e8c9deb69669f6c0187
Autor:
Xiangrong Geng, Chenguang Wang, Xin Gao, Pinki Chowdhury, Jonathan Weiss, José A. Villegas, Badeia Saed, Thilini Perera, Ying Hu, John Reneau, Maria Sverdlov, Ashley Wolfe, Noah Brown, Paul Harms, Nathanael G. Bailey, Kedar Inamdar, Alexandra C. Hristov, Trilokraj Tejasvi, Jaime Montes, Carlos Barrionuevo, Luis Taxa, Sandro Casavilca, J. Luís Alberto de Pádua Covas Lage, Hebert Fabrício Culler, Juliana Pereira, John S. Runge, Tingting Qin, Lam C. Tsoi, Hanna S. Hong, Li Zhang, Costas A. Lyssiotis, Rintaro Ohe, Tomomi Toubai, Alejandro Zevallos-Morales, Carlos Murga-Zamalloa, Ryan A. Wilcox
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 11, Pp 1-13 (2022)
Abstract Neoplasms originating from thymic T-cell progenitors and post-thymic mature T-cell subsets account for a minority of lymphoproliferative neoplasms. These T-cell derived neoplasms, while molecularly and genetically heterogeneous, exploit tran
Externí odkaz:
https://doaj.org/article/9ca6904e32104afcba2caaf8fce82226
Autor:
Christopher J. Halbrook, Galloway Thurston, Seth Boyer, Cecily Anaraki, Jennifer A. Jiménez, Amy McCarthy, Nina G. Steele, Samuel A. Kerk, Hanna S. Hong, Lin Lin, Fiona V. Law, Catherine Felton, Lorenzo Scipioni, Peter Sajjakulnukit, Anthony Andren, Alica K. Beutel, Rima Singh, Barbara S. Nelson, Fran Van Den Bergh, Abigail S. Krall, Peter J. Mullen, Li Zhang, Sandeep Batra, Jennifer P. Morton, Ben Z. Stanger, Heather R. Christofk, Michelle A. Digman, Daniel A. Beard, Andrea Viale, Ji Zhang, Howard C. Crawford, Marina Pasca di Magliano, Claus Jorgensen, Costas A. Lyssiotis
Publikováno v:
Nature cancer, vol 3, iss 11
Nature Cancer
Nature Cancer
The pancreatic tumor microenvironment drives deregulated nutrient availability. Accordingly, pancreatic cancer cells require metabolic adaptations to survive and proliferate. Pancreatic cancer subtypes have been characterized by transcriptional and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d1d8ab8d7e4958d9992ca11db28b89
https://doi.org/10.1038/s43018-022-00463-1
https://doi.org/10.1038/s43018-022-00463-1
Autor:
Rosa E Menjivar, Zeribe C Nwosu, Wenting Du, Katelyn L Donahue, Hanna S Hong, Carlos Espinoza, Kristee Brown, Ashley Velez-Delgado, Wei Yan, Fatima Lima, Allison Bischoff, Padma Kadiyala, Daniel Salas-Escabillas, Howard C Crawford, Filip Bednar, Eileen Carpenter, Yaqing Zhang, Christopher J Halbrook, Costas A Lyssiotis, Marina Pasca di Magliano
Publikováno v:
eLife. 12
An extensive fibroinflammatory stroma rich in macrophages is a hallmark of pancreatic cancer. In this disease, it is well appreciated that macrophages are immunosuppressive and contribute to the poor response to immunotherapy; however, the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48ac50b831ca12c788effc8e4537807
https://doi.org/10.7554/elife.80721
https://doi.org/10.7554/elife.80721
Autor:
Mack B. Reynolds, Hanna S. Hong, Britton C Michmerhuizen, Anna-Lisa E. Lawrence, Li Zhang, Jason S. Knight, Costas A. Lyssiotis, Basel H. Abuaita, Mary X. O’Riordan
Publikováno v:
Science Advances. 9
Macrophage metabolic plasticity enables repurposing of electron transport from energy generation to inflammation and host defense. Altered respiratory complex II function has been implicated in cancer, diabetes, and inflammation, but regulatory mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb8c045a261a992fa2b9971b7df6369
https://doi.org/10.1126/sciadv.ade8701
https://doi.org/10.1126/sciadv.ade8701
Autor:
Hanna S. Hong, Nneka E. Mbah, Mengrou Shan, Kristen Loesel, Lin Lin, Peter Sajjakulnukit, Luis O. Correa, Anthony Andren, Jason Lin, Atsushi Hayashi, Brian Magnuson, Judy Chen, Zhaoheng Li, Yuying Xie, Li Zhang, Daniel R. Goldstein, Shannon A. Carty, Yu Leo Lei, Anthony W. Opipari, Rafael J. Argüello, Ilona Kryczek, Nobuhiko Kamada, Weiping Zou, Luigi Franchi, Costas A. Lyssiotis
Publikováno v:
Science Immunology
Science Immunology, 2023, 7, ⟨10.1126/sciimmunol.abm8182⟩
Sci Immunol
Science Immunology, 2023, 7, ⟨10.1126/sciimmunol.abm8182⟩
Sci Immunol
T cell proliferation and cytokine production are bioenergetically and biosynthetically costly. The inability to meet these metabolic demands results in altered differentiation, accompanied by impaired effector function, and attrition of the immune re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a05d4a9e1c147f75d230beb3ade971
https://hal-amu.archives-ouvertes.fr/hal-04062465/file/nihms-1861567.pdf
https://hal-amu.archives-ouvertes.fr/hal-04062465/file/nihms-1861567.pdf
Autor:
Darren R. Heintzman, Joel Elasy, Channing Chi, Xiang Ye, Evan S. Krystoviak, Wasay Khan, Lana Olson, Angela Jones, Kelsey Voss, Andrew R. Patterson, Ayaka Sugiura, Frank M. Mason, Hanna S. Hong, Lindsay Bass, Katherine L. Beier, Wentao Deng, Costas A. Lyssiotis, Alexander G. Bick, W. Kimryn Rathmell, Jeffrey C. Rathmell
Heat is a cardinal feature of inflammation. Despite temperature variability and dependence of enzymes and complexes, how heat and fever affect immune cells remains uncertain. We found that heat broadly increased inflammatory activity of CD4+T cell su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58b80dffaeb56014c0a7e92eae5c7b0f
https://doi.org/10.1101/2022.11.14.516478
https://doi.org/10.1101/2022.11.14.516478
Autor:
Mack B. Reynolds, Hanna S. Hong, Britton C Michmerhuizen, Anna-Lisa E. Lawrence, Li Zhang, Jason S. Knight, Costas A. Lyssiotis, Basel H. Abuaita, Mary X. O’Riordan
Macrophage metabolic plasticity enables repurposing of electron transport from energy generation to inflammation and host defense. Altered Respiratory Complex II function has been implicated in cancer, diabetes and inflammation but regulatory mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d2a397689f695800312d18960585c6
https://doi.org/10.1101/2022.07.27.501734
https://doi.org/10.1101/2022.07.27.501734
Autor:
Katherine Z. Sanidad, Mohammed Amir, Aparna Ananthanarayanan, Anvita Singaraju, Nicholas B. Shiland, Hanna S. Hong, Nobuhiko Kamada, Naohiro Inohara, Gabriel Núñez, Melody Y. Zeng
Publikováno v:
Sci Immunol
The gut microbiome elicits antigen-specific immunoglobulin G (IgG) at steady state that cross-reacts to pathogens to confer protection against systemic infection. The role of gut microbiome–specific IgG antibodies in the development of the gut micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327e1d95049db4bdd2e374cec5e0fe04
https://doi.org/10.1126/sciimmunol.abh3816
https://doi.org/10.1126/sciimmunol.abh3816
Autor:
Nneka E. Mbah, Amy L. Myers, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Peter Sajjakulnukit, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zui, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
H3K27M diffuse intrinsic pontine gliomas (DIPG) exhibit cellular heterogeneity comprising less-differentiated, stem-like glioma cells that resemble oligodendrocyte precursors (OPC) and more differentiated astrocyte (AC)-like cells. H3K27M DIPG stem-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e09f2bbf821cb523eaab86fc14098b1
https://doi.org/10.1101/2022.03.01.482555
https://doi.org/10.1101/2022.03.01.482555