Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hanna Säkkinen"'
Autor:
Pasi Lehto, Sini Skarp, Taru Saukko, Hanna Säkkinen, Hannu Syrjälä, Risto Kerkelä, Samu Saarimäki, Sonja Bläuer, Katja Porvari, Lasse Pakanen, Jaana Karhu, Tero Ala-Kokko
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background Sepsis can lead to myocardial depression, playing a significant role in sepsis pathophysiology, clinical care, and outcome. To gain more insight into the pathophysiology of the myocardial response in sepsis, we investigated the ex
Externí odkaz:
https://doaj.org/article/506695c06c2d4e3d9f2376da1aee909c
Autor:
Elina Koivisto, Alicia Jurado Acosta, Anne-Mari Moilanen, Heikki Tokola, Jani Aro, Harri Pennanen, Hanna Säkkinen, Leena Kaikkonen, Heikki Ruskoaho, Jaana Rysä
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105168 (2014)
AimsActivating transcription factor 3 (ATF3) is a stress-activated immediate early gene suggested to have both detrimental and cardioprotective role in the heart. Here we studied the mechanisms of ATF3 activation by hypertrophic stimuli and ATF3 down
Externí odkaz:
https://doaj.org/article/ef4b1215b54849b98d95e7a1ea2f1836
Autor:
Hanna Leskinen, Hanna Säkkinen, Jaana Rysä, Heikki Ruskoaho, Jani Aro, E. Isopoussu, Heikki Tokola, Erja Mustonen
Publikováno v:
Acta Physiologica. 199:11-22
Aim: Accumulating evidence supports the concept that proinflammatory cytokines play an essential role in the failing heart. We examined the concomitant tumour necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 expression in myocytes in vitro
Autor:
Harri Pennanen, Hanna Säkkinen, Heikki Ruskoaho, Elina Koivisto, Jaana Rysä, Jani Aro, Alicia Jurado Acosta, Leena Kaikkonen, Anne-Mari Moilanen, Heikki Tokola
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105168 (2014)
PLoS ONE
PLoS ONE
AimsActivating transcription factor 3 (ATF3) is a stress-activated immediate early gene suggested to have both detrimental and cardioprotective role in the heart. Here we studied the mechanisms of ATF3 activation by hypertrophic stimuli and ATF3 down
Autor:
Pauli Ohukainen, Leena Kaikkonen, Heikki Tokola, Heikki Ruskoaho, Hanna Säkkinen, Jaana Rysä, Jani Aro, Juha Näpänkangas
Publikováno v:
Physiological Reports
Regenerating islet‐derived 3γ (Reg3γ) is a multifunctional protein, associated with various tissue injuries and inflammatory states. Since chronic inflammation is characteristics also for heart failure, the aim of this study was to characterize R