Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Hanna Rosenmann"'
Autor:
Kumudesh Mishra, Sahar Sweetat, Saja Baraghithy, Uri Sprecher, Monzer Marisat, Sultan Bastu, Hava Glickstein, Joseph Tam, Hanna Rosenmann, Miguel Weil, Edoardo Malfatti, Or Kakhlon
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 893 (2024)
Glycogen storage disease type III (GSDIII) is a hereditary glycogenosis caused by deficiency of the glycogen debranching enzyme (GDE), an enzyme, encoded by Agl, enabling glycogen degradation by catalyzing alpha-1,4-oligosaccharide side chain transfe
Externí odkaz:
https://doaj.org/article/73e5be5b00194bf9b242473aca67c83c
Autor:
Dorit Farfara, Meital Sooliman, Limor Avrahami, Tabitha Grace Royal, Shoshik Amram, Lea Rozenstein-Tsalkovich, Dorit Trudler, Shani Blanga-Kanfi, Hagit Eldar-Finkelman, Jens Pahnke, Hanna Rosenmann, Dan Frenkel
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Alzheimer’s disease (AD) is the leading cause of dementia in the world. The pathology of AD is affiliated with the elevation of both tau (τ) and β-amyloid (Aβ) pathologies. Yet, the direct link between natural τ expression o
Externí odkaz:
https://doaj.org/article/36f940c1cd774042b9dbd3ca9047e489
Autor:
Itia Samuel, Rachel Ben-Haroush Schyr, Yhara Arad, Tamar Attali, Shira Azulai, Michael Bergel, Aviv Halfon, Liron Hefetz, Tamir Hirsch, Hadar Israeli, Neta Lax, Keren Nitzan, Dana Sender, Sahar Sweetat, Eitan Okun, Hanna Rosenmann, Danny Ben-Zvi
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Obesity and hyperglycemia are risk factors for cognitive decline and for the development of Alzheimer’s Disease (AD). Bariatric surgery is an effective treatment for obesity that was shown to improve cognitive decline in obese patients. Bariatric s
Externí odkaz:
https://doaj.org/article/e0d878f1f6804a4e8c5b031336b02c0a
The Beneficial Effect of Mitochondrial Transfer Therapy in 5XFAD Mice via Liver–Serum–Brain Response
Autor:
Sahar Sweetat, Keren Nitzan, Nir Suissa, Yael Haimovich, Michal Lichtenstein, Samar Zabit, Sandrine Benhamron, Karameh Akarieh, Kumudesh Mishra, Dinorah Barasch, Ann Saada, Tamar Ziv, Or Kakhlon, Haya Lorberboum-Galski, Hanna Rosenmann
Publikováno v:
Cells, Vol 12, Iss 7, p 1006 (2023)
We recently reported the benefit of the IV transferring of active exogenous mitochondria in a short-term pharmacological AD (Alzheimer’s disease) model. We have now explored the efficacy of mitochondrial transfer in 5XFAD transgenic mice, aiming to
Externí odkaz:
https://doaj.org/article/ad084889ae3f4d2e8983db2220a9bcaf
Autor:
Or Kakhlon, Hilla Vaknin, Kumudesh Mishra, Jeevitha D’Souza, Monzer Marisat, Uri Sprecher, Shane Wald‐Altman, Anna Dukhovny, Yuval Raviv, Benny Da’adoosh, Hamutal Engel, Sandrine Benhamron, Keren Nitzan, Sahar Sweetat, Anna Permyakova, Anat Mordechai, Hasan Orhan Akman, Hanna Rosenmann, Alexander Lossos, Joseph Tam, Berge A. Minassian, Miguel Weil
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp n/a-n/a (2021)
Abstract This work employs adult polyglucosan body disease (APBD) models to explore the efficacy and mechanism of action of the polyglucosan‐reducing compound 144DG11. APBD is a glycogen storage disorder (GSD) caused by glycogen branching enzyme (G
Externí odkaz:
https://doaj.org/article/1a148de87c5d456f843b17754edc0627
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
Oxidative stress, particularly of mitochondrial origin, plays an important role in the pathogenesis of neurodegenerative disorders, including Alzheimer’s disease (AD) and other tauopathies. Controversies regarding the responses of tau phosphorylati
Externí odkaz:
https://doaj.org/article/0353fa81e1414b90bc8cd6ebfef48aa3
Autor:
Michael Valitsky, Sandrine Benhamron, Keren Nitzan, Dimitrios Karussis, Ezra Ella, Oded Abramsky, Ibrahim Kassis, Hanna Rosenmann
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1793 (2019)
The complexity of central nervous system (CNS) degenerative/inflammatory diseases and the lack of substantially effective treatments point to the need for a broader therapeutic approach to target multiple components involved in the disease pathogenes
Externí odkaz:
https://doaj.org/article/56dfee0736234d2f804718a063cbe357
NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model
Autor:
Natalia Shiryaev, Yan Jouroukhin, Eliezer Giladi, Eleni Polyzoidou, Nikolaos C. Grigoriadis, Hanna Rosenmann, Illana Gozes
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 2, Pp 381-388 (2009)
NAP (NAPVSIPQ) provides broad neuroprotection through microtubule interaction. Here, NAP was investigated for neuroprotection in an in vivo tauopathy model. Transgenic mice (2-month-old) that express the human double mutant tau protein [P301S;K257T]
Externí odkaz:
https://doaj.org/article/0b1f238518e24021aab76d3b7b005543
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/0c34c0d7595047859448f7d592c6c0ba
Autor:
Daniel Safadi, Oren S Cohen, Joab Chapman, Hanna Rosenmann, Zeev Nitsan, Esther Kahan, Shmuel Appel, Marwan Alkrenawi
Publikováno v:
Neurological Research. :1-4