Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Hanna Romanowicz-Makowska"'
Autor:
Hanna Romanowicz-Makowska, Beata Smolarz, Amer Houli, Bożena Góralczyk, Ireneusz Połać, Krzysztof Szyłło
Publikováno v:
Menopause Review, Vol 15, Iss 3, Pp 191-196 (2011)
Background: Endometrial cancer is one of the most common malignant neoplasms which appear in the uterine body. X-ray repair cross-complementing 1 (XRCC1) protein can be involved in the repair of DNA lesions, which are known to contribute to endometri
Externí odkaz:
https://doaj.org/article/4db21778503e4cfab712e4500bbc24f3
Autor:
Hanna Romanowicz-Makowska, Beata Smolarz, Bożena Góralczyk, Kinga Mroziewicz, Ireneusz Połać, Krzysztof Szyłło, Andrzej Kulig
Publikováno v:
Menopause Review, Vol 14, Iss 6, Pp 366-370 (2010)
Background: Single nucleotide polymorphisms in DNA base excision repair (BER) system such as: hOGG1and XRCC1 genes have been extensively studied in the association with various cancers. Material and methods: In the present study hOGG1 Ser326Cys and X
Externí odkaz:
https://doaj.org/article/5c7d6403ff054fad91999133efaaee8f
Autor:
Marek Zadrożny, Bogusław Westfal, Rafał Maciejczyk, Jakub Baszczyński, Beata Smolarz, Ireneusz Połać, Hanna Romanowicz-Makowska
Publikováno v:
Menopause Review, Vol 14, Iss 5, Pp 296-299 (2010)
Aim: Breast cancer is one of the major killers worldwide. Aberrant double-stranded break (DSB) repair leads to genomic instability, which is a hallmark of malignant cells. Double-stranded breaks are repaired by two pathways: homologous recombination
Externí odkaz:
https://doaj.org/article/d04cdd81ddd64e5e8762d457b305cc6a
Autor:
Magdalena Bryś, Krzysztof Szytto, Hanna Romanowicz-Makowska, Zbigniew Dobrowolski, Izabela Mastowska, Wanda Krajewska
Publikováno v:
São Paulo Medical Journal, Vol 127, Iss 3, Pp 128-133
CONTEXT AND OBJECTIVE: Estriol is an estrogen with considerably weaker stimulatory effects on endometrial proliferation than estradiol. A study was conducted to determine the level of estrogen receptors (ERs) and progesterone receptors (PRs) in women
Externí odkaz:
https://doaj.org/article/f21a0f58a81d4d9da6eee0dd0fe2ccfa
Autor:
Ewa Forma, Wanda M. Krajewska, Hanna Romanowicz-Makowska, Maria Nowacka-Zawisza, Anna Urbańska, Magdalena Bryś
Publikováno v:
Open Life Sciences, Vol 9, Iss 9, Pp 833-840 (2014)
Background Genetic variants in hormone receptor genes may be crucial predisposing factors for breast cancer, and microsatellites in the androgen receptor gene (AR) have been suggested to play a role. The aim of the study was to determine the associat
Autor:
Agnieszka Szymczyk, Waldemar Różański, Beata Smolarz, Paweł Jóźwiak, Magdalena Bryś, Ewa Brzeziańska, Hanna Romanowicz-Makowska, Grażyna Chwatko, Anna Krześlak, Ewa Forma
Publikováno v:
Molecular Biology Reports
Topoisomerase IIb binding protein 1 (TopBP1) is involved in cell survival, DNA replication, DNA damage repair and cell cycle checkpoint control. The biological function of TopBP1 and its close relation with BRCA1 prompted us to investigate whether al
Autor:
Marek Zadrożny, Ewa Mojs, Dariusz Samulak, Joanna Duda-Szymańska, Magdalena Bryś, Magdalena M. Michalska, Beata Smolarz, Marianna Makowska, Hanna Romanowicz-Makowska, Ewa Forma
Publikováno v:
Polish Journal of Pathology. 1:39-43
The most lethal damage for the cell among all damage is double-strand breaks (DSB) of DNA. DSB cause development of cancer diseases including the triple-negative mo - lecular subtype of breast cancer. The aim of this work was to evaluate the single n
Autor:
Hanna Romanowicz-Makowska, Marek Zadrożny, Ewa Mojs, Magdalena M. Michalska, Tomasz Krawczyk, Dariusz Samulak, Bogusław Westfal, Rafał Maciejczyk, Maciej Wilczak, Beata Smolarz
Publikováno v:
Polish Journal of Pathology. 2:104-108
Sentinel lymph node (SLN) biopsy is a part of the staging procedure in breast cancer patients. Intraoperative molecular analysis for SLN metastases using the one-step nucleic acid amplification (OSNA) method based on reverse-transcription loop-mediat
Autor:
Magdalena Bryś, Anna Krześlak, Beata Smolarz, Waldemar Różański, Ewa Forma, Hanna Romanowicz-Makowska, Agnieszka Szymczyk, Paweł Jóźwiak
Publikováno v:
Clinical and Experimental Medicine
Metallothioneins (MTs) are a family of metal binding proteins that play an important role in cellular processes such as proliferation and apoptosis. Metallothionein 2A is the most expressed MT isoform in the breast cells. A number of studies have dem
Publikováno v:
Molecular Biology Reports
TopBP1 protein displays structural as well as functional similarities to BRCA1 and is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. Aberrant expression of TopBP1 may lead to genomic instability and can ha