Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hanna Regus-Leidig"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Vision is our primary sense, and maintaining it throughout our lifespan is crucial for our well-being. However, the retina, which initiates vision, suffers from an age-related, irreversible functional decline. What causes this functional decline, and
Externí odkaz:
https://doaj.org/article/13df7445e6b74d43bc7314596f6c8259
Autor:
Hanna Regus-Leidig, Jenny Atorf, Andreas Feigenspan, Jan Kremers, Marion A Maw, Johann Helmut Brandstätter
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86769 (2014)
Light-dependent conductance changes of voltage-gated Cav1.4 channels regulate neurotransmitter release at photoreceptor ribbon synapses. Mutations in the human CACNA1F gene encoding the α1F subunit of Cav1.4 channels cause an incomplete form of X-li
Externí odkaz:
https://doaj.org/article/b688b3da90ea4f36ad2ccdd470982b1a
Autor:
Hanna Regus-Leidig, Corinna Ott, Martina Löhner, Jenny Atorf, Michaela Fuchs, Tina Sedmak, Jan Kremers, Anna Fejtová, Eckart D Gundelfinger, Johann H Brandstätter
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70373 (2013)
Piccolo is one of the largest cytomatrix proteins present at active zones of chemical synapses, where it is suggested to play a role in recruiting and integrating molecules relevant for both synaptic vesicle exo- and endocytosis. Here we examined the
Externí odkaz:
https://doaj.org/article/7ddd2bc1cfc2447e997914e76b64c22c
Autor:
Frederique Varoqueaux, Jan Kremers, Julia von Wittgenstein, Anneka Joachimsthaler, Benjamin H. Cooper, Johann Helmut Brandstätter, Maike Hemmerlein, Kaspar Gierke, Jenny Atorf, Hanna Regus-Leidig
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7848, p 7848 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences
Volume 21
Issue 21
Munc13 isoforms are constituents of the presynaptic compartment of chemical synapses, where they govern important steps in preparing synaptic vesicles for exocytosis. The role of Munc13-1, -2 and -3 is well documented in brain neurons, but less is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b949c479a54c2a24f0b6814ece1d0199
https://www.mdpi.com/1422-0067/21/21/7848
https://www.mdpi.com/1422-0067/21/21/7848
Autor:
Hanna Regus-Leidig, Anneka Joachimsthaler, Andreas Feigenspan, Martina Löhner, Johann Helmut Brandstätter, Kaspar Gierke, Jan Kremers, Susanne Schoch, Jenny Atorf, Tanja M. Müller, Henrik Martens, Angela Peukert, Norbert Babai
Publikováno v:
The Journal of Neuroscience. 37:7848-7863
RAB3A-interacting molecule (RIM) proteins are important regulators of transmitter release from active zones. At conventional chemical synapses, RIMs contribute substantially to vesicle priming and docking and their loss reduces the readily releasable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a68f20d5cb4f5b72183eae70e61175
https://doi.org/10.1523/jneurosci.2795-16.2017
https://doi.org/10.1523/jneurosci.2795-16.2017
Autor:
Craig C. Garner, Frauke Ackermann, Zsuzsanna Izsvák, Tanja M. Müller, Jan Kremers, F. Kent Hamra, Kaspar Gierke, Heinrich Sticht, Johann Helmut Brandstätter, Hanna Regus-Leidig, Anna Fejtova, Anneka Joachimsthaler
Publikováno v:
The journal of neuroscience 39(14), 2606-2619 (2019). doi:10.1523/JNEUROSCI.2038-18.2019
Active zones at chemical synapses are highly specialized sites for the regulated release of neurotransmitters. Despite a high degree of active zone protein conservation in vertebrates, every type of chemical synapse expresses a given set of protein i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd145185aa81978442f0e374e6c78d3f
Autor:
Nathalie, Falk, Kristin, Kessler, Sinja-Fee, Schramm, Karsten, Boldt, Elvir, Becirovic, Stylianos, Michalakis, Hanna, Regus-Leidig, Angelika A, Noegel, Marius, Ueffing, Christian T, Thiel, Ronald, Roepman, Johann Helmut, Brandstätter, Andreas, Gießl
Publikováno v:
Journal of cell science. 131(16)
Pericentrin (Pcnt) is a multifunctional scaffold protein and mutations in the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ae288f3098f4a059b903bb81d29af42
https://pubmed.ncbi.nlm.nih.gov/30054381
https://pubmed.ncbi.nlm.nih.gov/30054381
Autor:
Nathalie Falk, Elvir Becirovic, Johann Helmut Brandstätter, Marius Ueffing, Kristin Kessler, Stylianos Michalakis, Christian Thiel, Hanna Regus-Leidig, Sinja-Fee Schramm, Karsten Boldt, Ronald Roepman, Andreas Gießl, Angelika A. Noegel
Publikováno v:
Journal of Cell Science.
Pericentrin (Pcnt) is a multifunctional scaffold protein and mutations in the human PCNT gene are associated with several diseases, including ciliopathies. Pcnt plays a crucial role in ciliary development in olfactory receptor neurons, but its functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdcb23b03073c3f601fac336267e9e76
https://doi.org/10.1242/jcs.218487
https://doi.org/10.1242/jcs.218487
Autor:
Andreas Feigenspan, Tanja M. Müller, Johann Helmut Brandstätter, Hanna Regus-Leidig, Kaspar Gierke, Norbert Babai
Publikováno v:
Acta Physiologica. 226:e13241
Aim A key feature of the mammalian retina is the segregation of visual information in parallel pathways, starting at the photoreceptor terminals. Cone photoreceptors establish synaptic contacts with On bipolar and horizontal cells at invaginating, ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6751b71de8134be1848d9c2b43b3ece4
https://doi.org/10.1111/apha.13241
https://doi.org/10.1111/apha.13241
Autor:
Norbert Babai, Andreas Feigenspan, Kerstin Reim, Nils Brose, Michaela Fuchs, Hanna Regus-Leidig, Jasmin Mertins, Johann Helmut Brandstätter, Anna Sendelbeck
Publikováno v:
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Complexins (Cplxs) are SNARE complex regulators controlling the speed and Ca(2+) sensitivity of SNARE-mediated synaptic vesicle fusion. We have shown previously that photoreceptor ribbon synapses in mouse retina are equipped with Cplx3 and Cplx4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cc3470fbfeac04512c32c92c2ec944
https://hdl.handle.net/11858/00-001M-0000-002C-1052-B11858/00-001M-0000-002C-1054-7
https://hdl.handle.net/11858/00-001M-0000-002C-1052-B11858/00-001M-0000-002C-1054-7