Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Hanna Rajala"'
Autor:
Jani Huuhtanen, Sofie Lundgren, Mikko Keränen, Xingim Feng, Alina Dulau-Florea, Bhavisha Patel, Yoshitaka Zaimoku, Cassandra Kerr, Emmi Jokinen, Markus Heinonen, Hanna Rajala, Sanna Siitonen, Freja Ebeling, Georgina Ryland, Lucy Fox, Piers Blombery, Eva Hellström-Lindberg, Jaroslaw P. Maciejewski, Neal S. Young, Harri Lähdesmäki, Satu Mustjoki
Publikováno v:
HemaSphere, Vol 7, p e2285644 (2023)
Externí odkaz:
https://doaj.org/article/e86b35d4b8084784b622157a832f1600
Autor:
Jani Huuhtanen, Dipabarna Bhattacharya, Tapio Lönnberg, Matti Kankainen, Cassandra Kerr, Jason Theodoropoulos, Hanna Rajala, Carmelo Gurnari, Tiina Kasanen, Till Braun, Antonella Teramo, Renato Zambello, Marco Herling, Fumihiro Ishida, Toru Kawakami, Marko Salmi, Thomas Loughran, Jaroslaw P. Maciejewski, Harri Lähdesmäki, Tiina Kelkka, Satu Mustjoki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
T cell large granular lymphocytic leukemia (T-LGLL) is a lymphoproliferative disorder involving clonally expanded T cell clones and is not fully understood. Here the authors show that the rest of the immune repertoire is interconnected with the T-LGL
Externí odkaz:
https://doaj.org/article/f672b9429b1944109879f38760c24199
Autor:
Tiina Kelkka, Mikko Tyster, Sofie Lundgren, Xingmin Feng, Cassandra Kerr, Kohei Hosokawa, Jani Huuhtanen, Mikko Keränen, Bhavisha Patel, Toru Kawakami, Yuka Maeda, Otso Nieminen, Tiina Kasanen, Pasi Aronen, Bhagwan Yadav, Hanna Rajala, Hideyuki Nakazawa, Taina Jaatinen, Eva Hellström-Lindberg, Seishi Ogawa, Fumihiro Ishida, Hiroyoshi Nishikawa, Shinji Nakao, Jaroslaw Maciejewski, Neal S. Young, Satu Mustjoki
In immune aplastic anemia (IAA), severe pancytopenia results from the immune-mediated destruction of hematopoietic stem cells. Several autoantibodies have been reported, but no clinically applicable autoantibody tests are available for IAA. We screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b0ae054178b860b526a78bf5b6f4ee
http://hdl.handle.net/10138/347701
http://hdl.handle.net/10138/347701
Autor:
Sofie Lundgren, Timo Järvinen, Mikko A Keränen, Jason Theodoropoulos, Daehong Kim, Urpu Salmenniemi, Gunilla Walldin, Paula Savola, Tiina Kelkka, Hanna Rajala, Pekka Ellonen, Eva Hellström-Lindberg, Maija Itälä-Remes, Mikko Myllymäki, Matti Kankainen, Satu Mustjoki
Publikováno v:
Blood. 140:5496-5497
Autor:
Tiina Kelkka, Mikko Tyster, Sofie Lundgren, Xingmin Feng, Cassandra Kerr, Kohei Hosokawa, Jani Huuhtanen, Mikko Keränen, Toru Kawakami, Bhavisha Patel, Yuka Maeda, Otso Nieminen, Tiina Kasanen, Pasi Aronen, Bhagwan Yadav, Hanna Rajala, Hideyuki Nakazawa, Taina Jaatinen, Eva Hellstrom-Lindberg, Seishi Ogawa, Fumihiro Ishida, Hiroyoshi Nishikawa, Shinji Nakao, Jaroslaw Maciejewski, Neal S. Young, Satu Mustjoki
In immune aplastic anemia (IAA), severe pancytopenia results from the immune-mediated destruction of hematopoietic stem cells. Several autoantibodies have been reported, but no clinically applicable autoantibody tests are available for IAA. We screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921ce0295c9b9bad6470c313559fe0e3
https://doi.org/10.21203/rs.3.rs-1653776/v1
https://doi.org/10.21203/rs.3.rs-1653776/v1
Autor:
Satu Mustjoki, Giljun Park, Mikko Myllymäki, Matti Kankainen, Hanna Rajala, Bishwa Ghimire, Wing C. Chan, Jani Huuhtanen, Richard Moriggl, Daehong Kim
Publikováno v:
Leukemia
Large granular lymphocyte leukemia (LGLL) is characterized by somatic gain-of-function STAT3 mutations. However, the functional effects of STAT3 mutations on primary LGLL cells have not been studied in detail. In this study, we show that CD8+ T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23950a89e62ac3baa29614ac10c234c1
http://hdl.handle.net/10138/340467
http://hdl.handle.net/10138/340467
Autor:
Jani, Huuhtanen, Dipabarna, Bhattacharya, Tapio, Lönnberg, Matti, Kankainen, Cassandra, Kerr, Jason, Theodoropoulos, Hanna, Rajala, Carmelo, Gurnari, Tiina, Kasanen, Till, Braun, Antonella, Teramo, Renato, Zambello, Marco, Herling, Fumihiro, Ishida, Toru, Kawakami, Marko, Salmi, Thomas, Loughran, Jaroslaw P, Maciejewski, Harri, Lähdesmäki, Tiina, Kelkka, Satu, Mustjoki
Publikováno v:
Nature communications. 13(1)
T cell large granular lymphocytic leukemia (T-LGLL) is a rare lymphoproliferative disorder of mature, clonally expanded T cells, where somatic-activating STAT3 mutations are common. Although T-LGLL has been described as a chronic T cell response to a
Autor:
Hanna Rajala, Mikko A. I. Keränen, Riikka Räty, Veli-Jukka Anttila, Ulla Wartiovaara-Kautto, Mikko Haapio
Publikováno v:
Case Reports in Hematology, Vol 2021 (2021)
Case Reports in Hematology
Case Reports in Hematology
Gemtuzumab-ozogamicin (GO) is a humanized anti-CD33 antibody, which is conjugated to a cytotoxic calicheamicin. It is used to treat acute myeloid leukemia (AML) in combination with chemotherapy. We describe here two GO-treated acute myeloid leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7ac6646119ea8d6b2e640716beaf82
http://hdl.handle.net/10138/330556
http://hdl.handle.net/10138/330556
Autor:
Satu Mustjoki, Pekka Ellonen, Eva Hellström-Lindberg, Hanna Rajala, Sofie Lundgren, Jaroslaw P. Maciejewski, Freja Ebeling, Cassandra M Kerr, Neal S. Young, Gunilla Walldin, Sari Hannula, Matti Kankainen, Jani Huuhtanen, Oscar Brück, Harri Lähdesmäki, Mikko A. I. Keränen, Seishi Ogawa, Tiina Hannunen, Michael J. Clemente
Publikováno v:
Leukemia
Funding Information: Acknowledgements The authors would like to thank Hanna Läh-teenmäki, Tiina Kasanen, and Jay Klievink from the Hematology Research Unit Helsinki for valuable technical assistance. The authors would also like to thank Noora Aarni
Autor:
Hanna Rajala, Renato Zambello, Till Braun, Thomas P. Loughran, Satu Mustjoki, Tiina Kasanen, Cassandra M Kerr, Tiina Kelkka, Toru Kawakami, Harri Lähdesmäki, Antonella Teramo, Jason Theodoropoulos, Jaroslaw P. Maciejewski, Jani Huuhtanen, Marco Herling, Dipabarna Bhattacharya, Marko Salmi, Tapio Lönnberg, Fumihiro Ishida, Matti Kankainen
Publikováno v:
Blood. 138:1318-1318
Background: T-cell large granular lymphocytic leukemia (T-LGLL), a rare lymphoproliferative disorder of mature T cells, is characterized by the accumulation of activated effector T cells leading to a clonally restricted T-cell receptor (TCR) repertoi