Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hanna M. Miettinen"'
Autor:
Matti Viluksela, Päivi Heikkinen, Leo T M van der Ven, Filip Rendel, Robert Roos, Javier Esteban, Merja Korkalainen, Sanna Lensu, Hanna M Miettinen, Kari Savolainen, Satu Sankari, Hellmuth Lilienthal, Annika Adamsson, Jorma Toppari, Maria Herlin, Mikko Finnilä, Juha Tuukkanen, Heather A Leslie, Timo Hamers, Gerd Hamscher, Lauy Al-Anati, Ulla Stenius, Kine-Susann Dervola, Inger-Lise Bogen, Frode Fonnum, Patrik L Andersson, Dieter Schrenk, Krister Halldin, Helen Håkansson
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104639 (2014)
PCB 180 is a persistent non-dioxin-like polychlorinated biphenyl (NDL-PCB) abundantly present in food and the environment. Risk characterization of NDL-PCBs is confounded by the presence of highly potent dioxin-like impurities. We used ultrapure PCB
Externí odkaz:
https://doaj.org/article/bf5d98a2a2714b9eac8e5ee07feeb4f4
Autor:
Stephenie D. Prokopec, Paul C. Boutros, Hanna M. Miettinen, Raimo Pohjanvirta, Matti Viluksela
In rats, direct exposure to TCDD causes myriad toxicities. Exposed rats experience hepatotoxicity, wasting syndrome and immune suppression, amongst others. "Inherited exposure", as occurs in the F3 generation of directly exposed F0 animals, has also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a68c64b22c7a371d73e282c7f3f7b0b
https://zenodo.org/record/4013375
https://zenodo.org/record/4013375
Autor:
Sabrina B. Sholts, Merja Korkalainen, Hanna M. Miettinen, Ulla Simanainen, Helen Håkansson, Matti Viluksela
Publikováno v:
Toxicology. 337:30-38
In a previous study of female Han/Wistar (H/W) and Long-Evans (L-E) rats, we found that adult exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was associated with size decreases in the cranium and especially the face. In this study we compared
Autor:
Hanna M. Miettinen, Timo Jämsä, Juha Tuukkanen, Ulla Simanainen, Pasi Pulkkinen, Jouko Tuomisto, Matti Viluksela, Jaana Koistinen
Publikováno v:
Toxicological Sciences. 85:1003-1012
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a notorious model compound of highly toxic environmental pollutants, polychlorinated dibenzo-p-dioxins (PCDDs). Their toxic effects are mediated via cytosolic aryl hydrocarbon receptor (AHR). We studied t
Autor:
Anna-Maija Partanen, Hanna M. Miettinen, Jouni T. Tuomisto, Hannele Huuskonen, Päivi J. Miettinen, Jouko Tuomisto, Raimo Pohjanvirta
Publikováno v:
Toxicology Letters. 150:285-291
Dioxins are persistent environmental contaminants that cause multiple disorders in laboratory animals, including teratogenesis. In mice, the most important teratogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are hydronephrosis and cleft
Publikováno v:
Toxicology and Applied Pharmacology. 184:57-66
Effect of in Utero and Lactational 2,3,7,8-Tetrachlorodibenzo- p-dioxin Exposure on Rat Molar Development: The Role of Ex- posure Time. Miettinen, H. M., Alaluusua, S., Tuomisto, J., and Viluksela, M. (2002). Toxicol. Appl. Pharmacol. 184, 57- 66. We
Autor:
Gerd Hamscher, Hanna M. Miettinen, Satu Sankari, Heather A. Leslie, Dieter Schrenk, Helen Håkansson, Krister Halldin, Frode Fonnum, Ulla Stenius, Leo T.M. van der Ven, Kine-Susann Dervola, Robert Roos, Maria Herlin, Inger-Lise Bogen, Kari Savolainen, Mikko A. J. Finnilä, Filip Rendel, Hellmuth Lilienthal, Lauy Al-Anati, Patrik L. Andersson, Merja Korkalainen, Jorma Toppari, Timo Hamers, Päivi Heikkinen, Juha Tuukkanen, Matti Viluksela, Annika Adamsson, Sanna Lensu, Javier Esteban
Publikováno v:
PLoS ONE, 9(9). Public Library of Science
PLoS ONE, Vol 9, Iss 8, p e104639 (2014)
PLoS ONE
Viluksela, M, Heikkinen, P, van der Ven, L T M, Rendel, F, Roos, R, Estaban, J, Korkalainen, M, Lensu, S, Miettinen, M H, Savolainen, K, Sankari, S, Lilienthal, H, Adamsson, A, Toppari, J, Herlin, M, Finnilä, M, Tuukkanen, J, Leslie, H A, Hamers, T, Hamscher, G, Al-Anati, L, Stenius, U, Dervola, K S, Bogen, I L, Fonnum, F, Andersson, P L, Schrenk, D, Halldin, K & Håkansson, H 2014, ' Toxicological Profile of Ultrapure 2,2´,3,4,4´,5,5´-Heptachlorbiphenyl (PCB 180) in Adult Rats ', PLoS ONE, vol. 9, no. 9, pp. e104639 . https://doi.org/10.1371/journal.pone.0104639
PLoS ONE, Vol 9, Iss 8, p e104639 (2014)
PLoS ONE
Viluksela, M, Heikkinen, P, van der Ven, L T M, Rendel, F, Roos, R, Estaban, J, Korkalainen, M, Lensu, S, Miettinen, M H, Savolainen, K, Sankari, S, Lilienthal, H, Adamsson, A, Toppari, J, Herlin, M, Finnilä, M, Tuukkanen, J, Leslie, H A, Hamers, T, Hamscher, G, Al-Anati, L, Stenius, U, Dervola, K S, Bogen, I L, Fonnum, F, Andersson, P L, Schrenk, D, Halldin, K & Håkansson, H 2014, ' Toxicological Profile of Ultrapure 2,2´,3,4,4´,5,5´-Heptachlorbiphenyl (PCB 180) in Adult Rats ', PLoS ONE, vol. 9, no. 9, pp. e104639 . https://doi.org/10.1371/journal.pone.0104639
PCB 180 is a persistent non-dioxin-like polychlorinated biphenyl (NDL-PCB) abundantly present in food and the environment. Risk characterization of NDL-PCBs is confounded by the presence of highly potent dioxin-like impurities. We used ultrapure PCB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2cc7f98ce7294a30e5af52730293d44
https://research.vu.nl/en/publications/c42a02df-aa58-44ce-a915-ce4664b47e84
https://research.vu.nl/en/publications/c42a02df-aa58-44ce-a915-ce4664b47e84
Autor:
Helen Håkansson, Merja Korkalainen, Hanna M. Miettinen, Maria Herlin, Peter Zioupos, Juha Risteli, Mikko A. J. Finnilä, Juha Tuukkanen, Matti Viluksela, Timo Jämsä, Antti Aula
Publikováno v:
Toxicology and applied pharmacology. 273(1)
Bone is a target for high affinity aryl hydrocarbon receptor (AHR) ligands, such as dioxins. Although bone morphology, mineral density and strength are sensitive endpoints of dioxin toxicity, less is known about effects on bone microarchitecture and
Publikováno v:
The AH Receptor in Biology and Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa83a06a0b996216deb1cfe3ac85dc58
https://doi.org/10.1002/9781118140574.ch20
https://doi.org/10.1002/9781118140574.ch20
Autor:
Juha Tuukkanen, Matti Viluksela, Hanna M. Miettinen, Satu Alaluusua, Rita Sorvari, Mari Murtomaa
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 91(2)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), the model compound of polychlorinated dibenzo-p-dioxins and furans, is a potent toxicant with the ability to hamper development. Accidental exposure to TCDD has been linked with various developmental dental