Subjective cognitive complaints are related to depressive symptoms but not objective impairment in covert cerebral small vessel disease

Autor: Anne Arola, Hanna M. Laakso, Heidi Heinonen, Johanna Pitkänen, Matti Ahlström, Juha Lempiäinen, Teemu Paajanen, Jussi Virkkala, Juha Koikkalainen, Jyrki Lötjönen, Antti Korvenoja, Susanna Melkas, Hanna Jokinen

Publikováno v: Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100332- (2024)

Introduction: Subjective cognitive complaints are common in patients with cerebral small vessel disease (SVD), yet their correspondence to informant evaluations, objective cognitive functions and severity of brain changes are poorly understood. We st

Externí odkaz: https://doaj.org/article/28d376b01fe2404c9257f2f17d3be4f4

NEUROPSYCHIATRIC SYMPTOMS ACCELERATE COGNITIVE IMPAIRMENT ASSOCIATED WITH SMALL VESSEL DISEASE

Autor: Anne Arola, Tuuli Levänen, Hanna M. Laakso, Johanna Pitkänen, Juha Lempiäinen, Matti Ahlström, Juha Koikkalainen, Jyrki Lötjönen, Antti Korvenoja, Timo Erkinjuntti, Susanna Melkas, Hanna Jokinen

Publikováno v: Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100089- (2024)

Externí odkaz: https://doaj.org/article/de66f530acb6474a9d63bffa359d4ab2

Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease

Autor: Hanna M. Laakso, Juha Lempiäinen, Timo Erkinjuntti, Anne Arola, Antti Korvenoja, Teemu Paajanen, Jyrki Lötjönen, Sietske A.M. Sikkes, Hanna Jokinen, Matti Ahlström, Juha Koikkalainen, Johanna Pitkänen, Susanna Melkas

Publikováno v: European Journal of Neurology, 29(1), 158-167. Wiley-Blackwell
Jokinen, H, Laakso, H M, Ahlström, M, Arola, A, Lempiäinen, J, Pitkänen, J, Paajanen, T, Sikkes, S A M, Koikkalainen, J, Lötjönen, J, Korvenoja, A, Erkinjuntti, T & Melkas, S 2022, ' Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease ', European Journal of Neurology, vol. 29, no. 1, pp. 158-167 . https://doi.org/10.1111/ene.15108

ObjectiveCognitive and motor impairments are the key clinical manifestations of cerebral small vessel disease (SVD), but their interrelations and combined effects on functional outcome have not been elucidated. We investigated the associations betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf6aacc4fcafc8b8f7dd57370290c70
https://doi.org/10.1111/ene.15108

Global Burden of Small Vessel Disease-Related Brain Changes on MRI Predicts Cognitive and Functional Decline

Autor: Juha Koikkalainen, Hugues Chabriat, Susanna Melkas, Timo Erkinjuntti, Leonardo Pantoni, Frederik Barkhof, Ana Verdelho, Antti Korvenoja, Anders Wallin, Antti Brander, Daniel Rueckert, Sofia Madureira, Reinhold Schmidt, Jyrki Lötjönen, Philip Scheltens, Gunhild Waldemar, Lars-Olof Wahlund, John T. O'Brien, Hanna Jokinen, Franz Fazekas, Michael G. Hennerici, Tuomas Nieminen, Domenico Inzitari, Hanna M. Laakso

Publikováno v: Stroke
Stroke, 51(1), 170-178. Lippincott Williams and Wilkins
Jokinen, H, Koikkalainen, J, Laakso, H M, Melkas, S, Nieminen, T, Brander, A, Korvenoja, A, Rueckert, D, Barkhof, F, Scheltens, P, Schmidt, R, Fazekas, F, Madureira, S, Verdelho, A, Wallin, A, Wahlund, L-O, Waldemar, G, Chabriat, H, Hennerici, M, O'Brien, J, Inzitari, D, Lötjönen, J, Pantoni, L & Erkinjuntti, T 2020, ' Global Burden of Small Vessel Disease-Related Brain Changes on MRI Predicts Cognitive and Functional Decline ', Stroke, vol. 51, no. 1, pp. 170-178 . https://doi.org/10.1161/STROKEAHA.119.026170
Jokinen, H, Koikkalainen, J, Laakso, H M, Melkas, S, Nieminen, T, Brander, A, Korvenoja, A, Rueckert, D, Barkhof, F, Scheltens, P, Schmidt, R, Fazekas, F, Madureira, S, Verdelho, A, Wallin, A, Wahlund, L O, Waldemar, G, Chabriat, H, Hennerici, M, O'Brien, J, Inzitari, D, Lotjonen, J, Pantoni, L & Erkinjuntti, T 2020, ' Global Burden of Small Vessel Disease-Related Brain Changes on MRI Predicts Cognitive and Functional Decline ', Stroke, vol. 51, no. 1, pp. 170-178 . https://doi.org/10.1161/STROKEAHA.119.026170

Supplemental Digital Content is available in the text.
Background and Purpose— Cerebral small vessel disease is characterized by a wide range of focal and global brain changes. We used a magnetic resonance imaging segmentation tool to quantify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac9e78125af4bc7e44561a74761aed1
https://pubmed.ncbi.nlm.nih.gov/31776476

Executive function subdomains are associated with post-stroke functional outcome and permanent institutionalization

Autor: Raija Ylikoski, Marja Hietanen, Tarja Pohjasvaara, Hanna Jokinen, Sami Curtze, Gerli Sibolt, Timo Erkinjuntti, Susanna Melkas, Maarit Virta, Markku Kaste, Hanna M. Laakso

Publikováno v: European journal of neurology. 26(3)

Background and purposeImpairment of executive functions (EFs) is a common cognitive symptom post-stroke and affects independence in daily activities. Previous studies have often relied on brief cognitive tests not fully considering the wide spectrum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa9ee5c73d1542377c7d3eed6b44889
https://pubmed.ncbi.nlm.nih.gov/30414288