Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hanna Liao"'
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Nucleosome profiling from cell-free DNA (cfDNA) represents a potential approach for cancer detection and classification. Here, the authors develop Griffin, a computational framework for tumour subtype classification based on cfDNA nucleosome profilin
Externí odkaz:
https://doaj.org/article/a2aa19ff06af40648abe298b2dc9bb6b
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0c649e0ae1ad4fdc955cfa5df22bd466
Autor:
Jingxun Chen, Amy Tresenrider, Minghao Chia, David T McSwiggen, Gianpiero Spedale, Victoria Jorgensen, Hanna Liao, Folkert Jacobus van Werven, Elçin Ünal
Publikováno v:
eLife, Vol 6 (2017)
Differentiation programs such as meiosis depend on extensive gene regulation to mediate cellular morphogenesis. Meiosis requires transient removal of the outer kinetochore, the complex that connects microtubules to chromosomes. How the meiotic gene e
Externí odkaz:
https://doaj.org/article/7480204f0f8649d9832e1dee6c5fdc69
Autor:
Alison Paquette, Kylia Ahuna, Yeon Mi Hwang, Jocelynn Pearl, Hanna Liao, Paul Shannon, Leena Kadam, Samantha Lapehn, Matthew Bucher, Ryan Roper, Cory Funk, James MacDonald, Theo Bammler, Priyanka Baloni, Heather Brockway, W. Alex Mason, Nicole Bush, Kaja Z Lewinn, Catherine J Karr, John Stamatoyannopoulos, Louis J Muglia, Helen Jones, Yoel Sadovsky, Leslie Myatt, Sheela Sathyanarayana, Nathan D. Price
Gene regulation is essential to placental function and fetal development. We report a genome-scale transcriptional regulatory network (TRN) of the human placenta built using digital genomic footprinting and transcriptomic data. We integrated 475 tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa9b2b2d1c6e365f7e4d0fb1fb45ae00
https://doi.org/10.1101/2022.09.27.509541
https://doi.org/10.1101/2022.09.27.509541
Autor:
Matthew S. Wilken, Florian Busch, Zibo Chen, Ryan Kibler, Galen Dods, Vicki H. Wysocki, Christie Ciarlo, Mengxuan Jia, Hanna Liao, Michael C. Jewett, John A. Stamatoyannopoulos, Jocelynn R. Pearl, Basile I. M. Wicky, Shon Green, David Baker, Zachary L. VanAernum, Hana El-Samad, Scott E. Boyken, Andrew Hunt
Publikováno v:
Science
Designer gates Signaling in cells can occur through protein-protein interactions. Chen et al. describe the design of logic gates that can regulate protein association. The gates were built from small, designed proteins that all have a similar structu
Autor:
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publikováno v:
Nature communications. 13(1)
Cell-free DNA (cfDNA) has the potential to inform tumor subtype classification and help guide clinical precision oncology. Here we develop Griffin, a framework for profiling nucleosome protection and accessibility from cfDNA to study the phenotype of
Autor:
Jenny Kim Kim, Marko Jovanovic, Lori A. Kohlstaedt, Ryan M. Holly, Jingxun Chen, Elçin Ünal, Rena K. Evans, Emily Nicole Powers, Hanna Liao, Andrew Liao
Publikováno v:
Genes & development, vol 34, iss 3-4
Genes Dev
Genes Dev
The kinetochore complex is a conserved machinery that connects chromosomes to spindle microtubules. During meiosis, the kinetochore is restructured to accommodate a specialized chromosome segregation pattern. In budding yeast, meiotic kinetochore rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99450ba182deb323bf86784d335ea9e
https://escholarship.org/uc/item/0gh2x41c
https://escholarship.org/uc/item/0gh2x41c
Autor:
Victoria Jorgensen, Folkert J. van Werven, Minghao Chia, Hanna Liao, Elçin Ünal, Amy Tresenrider
SUMMARYLong Undecoded Transcript Isoforms (LUTIs) represent a class of non-canonical mRNAs that downregulate gene expression through the combined act of transcriptional and translational repression. While single gene studies revealed some important a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c393817cf5d61fd55b3c502be78991a
https://doi.org/10.1101/843458
https://doi.org/10.1101/843458
Autor:
Minghao Chia, Amy Tresenrider, Folkert J. van Werven, Victoria Jorgensen, Kaitlin Morse, Elçin Ünal, Hanna Liao
Publikováno v:
Molecular Cell
Summary Long undecoded transcript isoforms (LUTIs) represent a class of non-canonical mRNAs that downregulate gene expression through the combined act of transcriptional and translational repression. While single gene studies revealed important aspec
Autor:
Paz Polak, Gavin Ha, Anna-Lisa Doebley, Heather A. Parsons, Caroline Kikawa, Viktor A. Adalsteinsson, Eden Cruikshank, Minjeong Ko, Joseph B. Hiatt, Peter S. Nelson, Daniel G. Stover, David MacPherson, Anna C. H. Hoge, Navonil De Sarkar, Hanna Liao
Publikováno v:
Cancer Research. 81:LB022-LB022
Background: Cell-free DNA (cfDNA) is released from dying cells, including tumor cells, and can be isolated from peripheral blood for studying cancer. In the bloodstream, cfDNA is protected from degradation by nucleosomes and other DNA binding protein