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pro vyhledávání: '"Hanna L Zieger"'
Autor:
Hanna L Zieger, Daniel Choquet
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105453- (2021)
Neurodevelopmental disorders such as those linked to intellectual disabilities or autism spectrum disorder are thought to originate in part from genetic defects in synaptic proteins. Single gene mutations linked to synapse dysfunction can broadly be
Externí odkaz:
https://doaj.org/article/783dbbe3d1a0476799315fc803bc1f56
Autor:
Sophie Daburon, Agata Nowacka, Eric Hosy, Mathieu Ducros, Hanna L. Zieger, Matthieu Sainlos, Daniel Choquet, Mónica Fernández-Monreal, Angela M. Getz, Urielle François, Christelle Breillat, Frederic Lanore, Aurélie Lampin-Saint-Amaux, Yann Humeau
Publikováno v:
Science advances. 8(30)
SUMMARYRegulation of synaptic neurotransmitter receptor content is a fundamental mechanism for tuning synaptic efficacy during experience-dependent plasticity and behavioral adaptation. However, experimental approaches to track and modify receptor mo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific reports 10(1), 5709 (2020). doi:10.1038/s41598-020-62207-4
Scientific Reports
Scientific reports 10(1), 5709 (2020). doi:10.1038/s41598-020-62207-4
Scientific Reports
Scaffold proteins are responsible for structural organisation within cells; they form complexes with other proteins to facilitate signalling pathways and catalytic reactions. The scaffold protein connector enhancer of kinase suppressor of Ras 2 (CNK2
Autor:
Ahmadyar E, Bettina Schmerl, Nils Rademacher, Hanna L. Zieger, Stella-Amrei Kunde, Sarah A. Shoichet
We show here that the dynamics of the synaptic scaffold molecule SAP102 are negatively regulated by JNK inhibition, that SAP102 is a direct phosphorylation target of JNK3, and that SAP102 regulation by JNK is restricted to neurons that harbour mature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec93967343662e180f5223ad6cf3cff9
https://doi.org/10.1101/2021.04.30.442109
https://doi.org/10.1101/2021.04.30.442109
Publikováno v:
FEBS Open Bio
Synaptic α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors are essential mediators of neurotransmission in the central nervous system. Shisa9/cysteine-knot AMPAR modulating protein 44 (CKAMP44) is a transmembrane protein recently f
Autor:
Jean-Baptiste Sibarita, Hanna L. Zieger, Seksiri Arttamangkul, Terrence J. Sejnowski, Thomas M. Bartol, Eric Hosy, Mark von Zastrow, Damien Jullié, Miriam Carolin Stoeber
Publikováno v:
Neuron
Neuron, Elsevier, 2020, 105 (4), pp.663-677.e8. ⟨10.1016/j.neuron.2019.11.016⟩
Neuron (2019) pp. pii:S0896-6273(19)30979-1
Neuron, Elsevier, 2020, 105 (4), pp.663-677.e8. ⟨10.1016/j.neuron.2019.11.016⟩
Neuron (2019) pp. pii:S0896-6273(19)30979-1
A major function of GPCRs is to inhibit presynaptic neurotransmitter release, requiring ligand-activated receptors to couple locally to effectors at terminals. The current understanding of how this is achieved is through receptor immobilization on th
Scaffold proteins are responsible for structural organisation within cells; they form complexes with other proteins to facilitate signalling pathways and catalytic reactions. The scaffold protein connector enhancer of kinase suppressor of Ras 2 (CNK2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f023db65e0816e62924669d787b0aa4b
https://doi.org/10.1101/532374
https://doi.org/10.1101/532374
Autor:
Daniel Choquet, Hanna L Zieger
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2021, 158, pp.105453. ⟨10.1016/j.nbd.2021.105453⟩
Neurobiology of Disease, Vol 158, Iss, Pp 105453-(2021)
Neurobiology of Disease, Elsevier, 2021, 158, pp.105453. ⟨10.1016/j.nbd.2021.105453⟩
Neurobiology of Disease, Vol 158, Iss, Pp 105453-(2021)
Neurodevelopmental disorders such as those linked to intellectual disabilities or autism spectrum disorder are thought to originate in part from genetic defects in synaptic proteins. Single gene mutations linked to synapse dysfunction can broadly be