Differential protein expression profiles of cyst fluid from papillary thyroid carcinoma and benign thyroid lesions.

Autor: Andrii Dinets, Maria Pernemalm, Hanna Kjellin, Vitalijs Sviatoha, Anastasios Sofiadis, C Christofer Juhlin, Jan Zedenius, Catharina Larsson, Janne Lehtiö, Anders Höög

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0126472 (2015)

Cystic papillary thyroid carcinoma (cPTC) is a subgroup of PTC presenting a diagnostic challenge at fine needle aspiration biopsy (FNAB). To further investigate this entity we aimed to characterize protein profiles of cyst fluids from cPTC and benign

Externí odkaz: https://doaj.org/article/4e574891d850488492c4ddf30a6cb8f1

Altered expression of the

Autor: Patrick, Scicluna, Stefano, Caramuta, Hanna, Kjellin, Cheng, Xu, Robin, Fröbom, Monira, Akhtar, Jiwei, Gao, Hao, Shi, Magnus, Kjellman, Malin, Almgren, Anders, Höög, Jan, Zedenius, Tomas J, Ekström, Robert, Bränström, Weng-Onn, Lui, Catharina, Larsson

Publikováno v: International journal of oncology. 61(5)

Abnormalities of the insulin‑like growth factor 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d232bd8cb425acf52c09d810f0d85cb3
https://pubmed.ncbi.nlm.nih.gov/36169175

Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Autor: Na Wang, C. Christofer Juhlin, Hanna Kjellin, Janne Lehtiö, Dawei Xu, Omid Fotouhi, Anastasios Sofiadis, Jan Zedenius, Catharina Larsson, Martin Bäckdah

Publikováno v: Oncotarget

Medullary thyroid carcinomas (MTCs) exhibit telomerase activation in strong association with shorter patient survival. To understand the background of telomerase activation we quantified TERT copy numbers and TERT promoter methylation in 42 MTCs and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cffbfb947eb9155fc6c1a17c2383383
https://doi.org/10.18632/oncotarget.7237

Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors

Autor: Janne Lehtiö, Marta Mendiola, Angela Lamarca, C. Christofer Juhlin, Victoria Heredia Soto, Jan Zedenius, Ming Lu, Anders Höög, Hanna Kjellin, Jamileh Hashemi, Jorge Barriuso, Magnus Kjellman, Catharina Larsson, Omid Fotouhi, Laura G. Pastrián

Publikováno v: The Journal of Clinical Endocrinology and Metabolism
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Fotouhi, O, Kjellin, H, Larsson, C, Hashemi, J, Barriuso, J, Christofer Juhlin, C, Lu, M, Höög, A, Pastrián, L G, Lamarca, A, Soto, V H, Zedenius, J, Mendiola, M, Lehtiö, J & Kjellman, M 2016, ' Proteomics suggests a role for APC-survivin in response to somatostatin analog treatment of neuroendocrine tumors ', Journal of Clinical Endocrinology and Metabolism, vol. 101, no. 10, pp. 3616-3627 . https://doi.org/10.1210/jc.2016-2028

Context: Somatostatin analogs are established in the treatment of neuroendocrine tumors (NETs) including small intestinal NET; however, the molecular mechanisms are not well known. Here, we examined the direct effects of lanreotide in NET cell line m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dd7a445713c9e02a3d647d2a981712
https://pubmed.ncbi.nlm.nih.gov/27459532

Alterations in the membrane-associated proteome fraction of alveolar macrophages in sarcoidosis

Autor: Hanna, Kjellin, Ernesto, Silva, Rui Mamede, Branca, Anders, Eklund, Per-Johan, Jakobsson, Johan, Grunewald, Janne, Lehtiö, Åsa M, Wheelock

Publikováno v: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 33(1)

Alveolar macrophages are implicated in the pathogenesis of lung sarcoidosis. Their interaction with T-cells leads to an inflammatory response that may either resolve within 2 years, or become chronic with an increased risk to develop lung fibrosis.To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c0ca62058dc4ee3817746f9821a9fd67
https://pubmed.ncbi.nlm.nih.gov/27055832