Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hanna Kapica"'
Autor:
Joanna Fedorowicz, Dagmara Bazar, Wioletta Brankiewicz, Hanna Kapica, Krzesimir Ciura, Beata Zalewska-Piątek, Rafał Piątek, Krzysztof Cal, Krystyna Mojsiewicz-Pieńkowska, Jarosław Sączewski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Low-molecular synthetic fluorophores are convenient tools in bioimaging applications. Several derivatives of Safirinium dyes as well as their reactive N-hydroxysuccinimide (NHS) esters bearing diverse substituents were synthesized and evalua
Externí odkaz:
https://doaj.org/article/88b3e4bc78774a79b3501871801084a6
Autor:
Monika Pastewska, Beata Żołnowska, Strahinja Kovačević, Hanna Kapica, Maciej Gromelski, Filip Stoliński, Jarosław Sławiński, Wiesław Sawicki, Krzesimir Ciura
Publikováno v:
Molecules, Vol 27, Iss 13, p 3965 (2022)
Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work, reversed-phase high-performance liquid chromatography and biomimetic chromatography were applied
Externí odkaz:
https://doaj.org/article/e80ded7d0fcf4212a75d42b975af059c
Autor:
Krzesimir Ciura, Natalia Ptaszyńska, Hanna Kapica, Monika Pastewska, Anna Łęgowska, Krzysztof Rolka, Wojciech Kamysz, Wiesław Sawicki, Katarzyna E. Greber
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1237 (2021)
The emergence and spread of multiple drug-resistant bacteria strains caused the development of new antibiotics to be one of the most important challenges of medicinal chemistry. Despite many efforts, the commercial availability of peptide-based antim
Externí odkaz:
https://doaj.org/article/a815fb33af4e49919ec8c81dc3ae3c6f
Autor:
Krzesimir Ciura, Joanna Fedorowicz, Petar Žuvela, Mario Lovrić, Hanna Kapica, Paweł Baranowski, Wiesław Sawicki, Ming Wah Wong, Jarosław Sączewski
Publikováno v:
Molecules, Vol 25, Iss 20, p 4835 (2020)
Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in high demand owing to it enabling the approximation of the processes of absorption, distribution, metabolism, and elimination. Although the
Externí odkaz:
https://doaj.org/article/fe9601ce57504dbb9e82b9008fde9bc9
Autor:
Monika Pastewska, Beata Żołnowska, Strahinja Kovačević, Hanna Kapica, Jarosław Sławiński, Wiesław Sawicki, Krzesimir Ciura
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63168194bb87e040ecd2e7b0b26639ec
https://doi.org/10.2139/ssrn.3959684
https://doi.org/10.2139/ssrn.3959684
Autor:
Jarosław Sączewski, Joanna Fedorowicz, Petar Žuvela, Mario Lovrić, Ming Wah Wong, Paweł Baranowski, Hanna Kapica, Wiesław Sawicki, Krzesimir Ciura
Publikováno v:
Molecules, Vol 25, Iss 4835, p 4835 (2020)
Molecules
Molecules
Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in high demand owing to it enabling the approximation of the processes of absorption, distribution, metabolism, and elimination. Although the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf866069fb56b62123733810cf23bd4
https://www.mdpi.com/1420-3049/25/20/4835
https://www.mdpi.com/1420-3049/25/20/4835
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 188
The development of high-throughput methods for the estimation of physicochemical and biological properties of drug candidates is highly desired in the pharmaceutical landscape. Affinity to plasma protein is one of the most important biological proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba728289e7e07b33d14b835927bfe7b
https://pubmed.ncbi.nlm.nih.gov/32623315
https://pubmed.ncbi.nlm.nih.gov/32623315
Autor:
Strahinja Z. Kovačević, Krzesimir Ciura, Hanna Kapica, Martyna Kornela, Monika Pastewska, Wiesław Sawicki
Publikováno v:
Journal of Chromatography A. 1660:462666
Screening of physicochemical properties should be considered one of the essential steps in the drug discovery pipeline. Among the available methods, biomimetic chromatography with an immobilized artificial membrane is a powerful tool for simulating i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26986454eace8eac692a3adc0f01b7a6
https://doi.org/10.1016/j.chroma.2021.462666
https://doi.org/10.1016/j.chroma.2021.462666
Autor:
Katarzyna E. Greber, Hanna Kapica, Monika Pastewska, Wiesław Sawicki, Wojciech Kamysz, Krzysztof Rolka, Krzesimir Ciura, Natalia Ptaszyńska, Anna Łęgowska
Publikováno v:
Antibiotics, Vol 10, Iss 1237, p 1237 (2021)
Antibiotics
Antibiotics
The emergence and spread of multiple drug-resistant bacteria strains caused the development of new antibiotics to be one of the most important challenges of medicinal chemistry. Despite many efforts, the commercial availability of peptide-based antim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2c1ca3900f01ee711615f8a98d9ff9
https://doi.org/10.3390/antibiotics10101237
https://doi.org/10.3390/antibiotics10101237
Autor:
Szymon Ulenberg, Piotr Kawczak, Wiesław Sawicki, Barbara Bednarczyk-Cwynar, Paweł Georgiev, Krzesimir Ciura, Hanna Kapica, Natalia Buławska, Tomasz Bączek, Strahinja Z. Kovačević, Monika Pastewska
Publikováno v:
Journal of Chromatography A. 1656:462552
Naturally occurring molecules are excellent sources of lead compounds. A series of oleanolic acid (OA) derivatives previously synthesized in our laboratory, which show promising antitumor activity, have been analyzed in terms of lipophilicity evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72434de7aad33b9bcfc1bf174bda93c5
https://doi.org/10.1016/j.chroma.2021.462552
https://doi.org/10.1016/j.chroma.2021.462552