Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hanna K. L. Johansson"'
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Introduction: Adverse Outcome Pathways (AOPs) can support both testing and assessment of endocrine disruptors (EDs). There is, however, a need for further development of the AOP framework to improve its applicability in a regulatory context. Here we
Externí odkaz:
https://doaj.org/article/2c87a55f64a141cd9b42059b0dcd08b3
Autor:
Julie Boberg, Tianyi Li, Sofie Christiansen, Monica K. Draskau, Pauliina Damdimopoulou, Terje Svingen, Hanna K. L. Johansson
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
A prevailing challenge when testing chemicals for their potential to cause female reproductive toxicity is the lack of appropriate toxicological test methods. We hypothesized that starting a 28-day in vivo toxicity study already at weaning, instead o
Externí odkaz:
https://doaj.org/article/2eb25d633a484cf0bada57477de89306
Autor:
Delphine Franssen, Hanna K. L. Johansson, David Lopez-Rodriguez, Arnaud Lavergne, Quentin Terwagne, Julie Boberg, Sofie Christiansen, Terje Svingen, Anne-Simone Parent
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionEstrogenic endocrine disrupting chemicals (EDCs) such as diethylstilbestrol (DES) are known to alter the timing of puberty onset and reproductive function in females. Accumulating evidence suggests that steroid synthesis inhibitors such a
Externí odkaz:
https://doaj.org/article/2fcb2883243c44298bee497d3744ae73
Autor:
Majorie B. M. van Duursen, Julie Boberg, Sofie Christiansen, Lisa Connolly, Pauliina Damdimopoulou, Panagiotis Filis, Paul A. Fowler, Bart M. Gadella, Jan Holte, Kersti Jääger, Hanna K. L. Johansson, Tianyi Li, Séverine Mazaud-Guittot, Anne-Simone Parent, Andres Salumets, Ana M. Soto, Terje Svingen, Agne Velthut-Meikas, Eva Bay Wedebye, Yuling Xie, Martin van den Berg
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3215 (2020)
Currently available test methods are not well-suited for the identification of chemicals that disturb hormonal processes involved in female reproductive development and function. This renders women’s reproductive health at increasing risk globally,
Externí odkaz:
https://doaj.org/article/59e3e8d8e0a74e9aa2832d52639e6fb8
Autor:
Indusha Kugathas, Hanna K. L. Johansson, Edith Chan Sock Peng, Maryne Toupin, Bertrand Evrard, Thomas A. Darde, Julie Boberg, Monica K. Draskau, Antoine D. Rolland, Séverine Mazaud-Guittot, Frédéric Chalmel, Terje Svingen
Publikováno v:
Kugathas, I, Johansson, H K L, Chan Sock Peng, E, Toupin, M, Evrard, B, Darde, T A, Boberg, J, Draskau, M K, Rolland, A D, Mazaud-Guittot, S, Chalmel, F & Svingen, T 2023, ' Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole ', Archives of Toxicology, vol. 97, pp. 849-863 . https://doi.org/10.1007/s00204-023-03442-2
Archives of Toxicology
Archives of Toxicology, 2023, 97 (3), pp.849-863. ⟨10.1007/s00204-023-03442-2⟩
Archives of Toxicology
Archives of Toxicology, 2023, 97 (3), pp.849-863. ⟨10.1007/s00204-023-03442-2⟩
Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are assessed in rodent toxicity studies, a concern is that typical endpoints are not sensitive enou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc064d00a0564016fb619e64450e33a
https://orbit.dtu.dk/en/publications/3d1771d2-2852-4992-9796-cc5d695b3671
https://orbit.dtu.dk/en/publications/3d1771d2-2852-4992-9796-cc5d695b3671
Autor:
Julie, Boberg, Hanna K L, Johansson, Niels, Hadrup, Karin, Dreisig, Line, Berthelsen, Kristian, Almstrup, Anne Marie, Vinggaard, Ulla, Hass
Publikováno v:
The Prostate. 75(2)
Elevated levels of endogenous or exogenous estrogens during fetal life can induce permanent disturbances in prostate growth and predispose to precancerous lesions. Recent studies have indicated that also early anti-androgen exposure may affect prosta
Autor:
Nina, Cedergreen, Nils Jakob, Nørhave, Kristoffer, Nielsen, Hanna K L, Johansson, Helle, Marcussen, Claus, Svendsen, David J, Spurgeon
Publikováno v:
Environmental toxicology and chemistry. 32(10)
Knowledge about how toxicity changes with temperature is important for determining the extent of safety factors required when extrapolating from standard laboratory conditions to variable field scenarios. In the present study, the authors evaluated t