Výsledky vyhledávání - "Hanna Jechle"

Structure-metabolism relationships of valine and tert-leucine-derived synthetic cannabinoid receptor agonists: a systematic comparison of the in vitro phase I metabolism using pooled human liver microsomes and high-resolution mass spectrometry

Autor: Michael Kassiou, Volker Auwärter, Verena Angerer, Mitchell Longworth, Laura M. Huppertz, Hanna Jechle, Manfred Jung, Florian Franz, Maurice Wilde

Publikováno v: Forensic Toxicology. 37:316-329

Synthetic cannabinoid receptor agonists, commonly referred to as ‘synthetic cannabinoids’ (SCs), gained popularity as recreational drugs due to their cannabis-like effects. The subclass of valine or tert-leucine-derived SCs has dominated the ‘d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8964c56e039c08088d4f1c13441df233
https://doi.org/10.1007/s11419-018-00462-x

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Synthetic cannabinoids in hair – Pragmatic approach for method updates, compound prevalences and concentration ranges in authentic hair samples

Autor: Melanie Pegoro, Volker Auwärter, Merja A. Neukamm, Florian Franz, Hanna Jechle, Verena Angerer

Publikováno v: Analytica Chimica Acta. 1006:61-73

Since the first detection of synthetic cannabinoids (SCs) in so-called ‘legal high’ products (e.g. ‘Spice’) sold as legal alternatives to marihuana, the rapid development of this class of designer drugs poses a great challenge for analytical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9d95759986abe341b670e80b289c36
https://doi.org/10.1016/j.aca.2017.12.029

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Immunoassay screening in urine for synthetic cannabinoids – an evaluation of the diagnostic efficiency

Autor: Bjoern Moosmann, Melanie Pegoro, Christian Schlögl, Reinhard Mielke, David Janele, Ralf Zehnle, Hanna Jechle, Verena Angerer, Volker Auwärter, Georg Weinfurtner, Harald Ertl, Stefan Gerl, Matthias Wagner, Florian Franz, Matthias Friedl

Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM). 55

Background:The abuse of synthetic cannabinoids (SCs) as presumed legal alternative to cannabis poses a great risk to public health. For economic reasons many laboratories use immunoassays (IAs) to screen for these substances in urine. However, the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e92e757356413cebbd3d66d0749c76f
https://doi.org/10.1515/cclm-2016-0831

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