Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hanna Janicki"'
Autor:
Meryem Seda Ercanoglu, Lutz Gieselmann, Sabrina Dähling, Nareshkumar Poopalasingam, Susanne Detmer, Manuel Koch, Michael Korenkov, Sandro Halwe, Michael Klüver, Veronica Di Cristanziano, Hanna Janicki, Maike Schlotz, Johanna Worczinski, Birgit Gathof, Henning Gruell, Matthias Zehner, Stephan Becker, Kanika Vanshylla, Christoph Kreer, Florian Klein
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103951- (2022)
Summary: Preexisting immunity against SARS-CoV-2 may have critical implications for our understanding of COVID-19 susceptibility and severity. The presence and clinical relevance of a preexisting B cell immunity remain to be fully elucidated. Here, w
Externí odkaz:
https://doaj.org/article/2404de6fd5954a088328929e1de3cfe8
Autor:
Michael Korenkov, Matthias Zehner, Hadas Cohen-Dvashi, Aliza Borenstein-Katz, Lisa Kottege, Hanna Janicki, Kanika Vanshylla, Timm Weber, Henning Gruell, Manuel Koch, Ron Diskin, Christoph Kreer, Florian Klein
SUMMARYSomatic hypermutation (SHM) drives affinity maturation and continues over months in SARS-CoV-2 neutralizing antibodies. Yet, several potent SARS-CoV-2 antibodies carry no or only few mutations, leaving the question of how ongoing SHM affects n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2dd49e1b27917e34bc1d395ad127da3
https://doi.org/10.1101/2023.05.09.539943
https://doi.org/10.1101/2023.05.09.539943
Autor:
Henning Gruell, Kanika Vanshylla, Michael Korenkov, Pinkus Tober-Lau, Matthias Zehner, Friederike Münn, Hanna Janicki, Max Augustin, Philipp Schommers, Leif Erik Sander, Florian Kurth, Christoph Kreer, Florian Klein
SARS-CoV-2 neutralizing antibodies play a critical role in prevention and treatment of COVID-19 but are challenged by viral evolution and antibody evasion, exemplified by the highly resistant Omicron BA.1 sublineage.1–12 Importantly, the recently i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9143827d7bd53b756107a4ed4bbedd2d
https://doi.org/10.1101/2022.04.06.487257
https://doi.org/10.1101/2022.04.06.487257
Autor:
Henning Gruell, Kanika Vanshylla, Michael Korenkov, Pinkus Tober-Lau, Matthias Zehner, Friederike Münn, Hanna Janicki, Max Augustin, Philipp Schommers, Leif Erik Sander, Florian Kurth, Christoph Kreer, Florian Klein
Publikováno v:
Cell hostmicrobe. 30(9)
SARS-CoV-2 neutralizing antibodies play a critical role in COVID-19 prevention and treatment but are challenged by viral evolution and the emergence of novel escape variants. Importantly, the recently identified Omicron sublineages BA.2.12.1 and BA.4
Autor:
Artem Ashurov, Timm Weber, Alexandra Kupke, Hanna Janicki, Nico Pfeifer, Reinhild Brinker, Hadas Cohen-Dvashi, Jan Mathis Eckert, Simone Lederer, Meryem S. Ercanoglu, Cornelius Rohde, Stephan Becker, Veronica Di Cristanziano, Maria J G T Vehreschild, Clemens M. Wendtner, Manuel Koch, Florian Klein, Sandro Halwe, Christoph Kreer, Philipp Schommers, Matthias Zehner, Kanika Vanshylla, Verena Krähling, Henning Gruell, M. Korenkov, Lutz Gieselmann, Timo Wolf, Ron Diskin
Publikováno v:
Cell
Summary The SARS-CoV-2 pandemic has unprecedented implications for public health, social life, and the world economy. Because approved drugs and vaccines are limited or not available, new options for COVID-19 treatment and prevention are in high dema
Autor:
Meryem Seda Ercanoglu, Lutz Gieselmann, Sabrina Dähling, Nareshkumar Poopalasingam, Susanne Detmer, Manuel Koch, Michael Korenkov, Sandro Halwe, Michael Klüver, Veronica Di Cristanziano, Hanna Janicki, Maike Schlotz, Johanna Worczinski, Birgit Gathof, Henning Gruell, Matthias Zehner, Stephan Becker, Kanika Vanshylla, Christoph Kreer, Florian Klein
Publikováno v:
iScience. 25(3)
Preexisting immunity against SARS-CoV-2 may have critical implications for our understanding of COVID-19 susceptibility and severity. The presence and clinical relevance of a preexisting B cell immunity remain to be fully elucidated. Here, we provide
Autor:
Meryem S. Ercanoglu, Veronica Di Cristanziano, M. Korenkov, Ursula Hanna Janicki, Nareshkumar Poopalasingam, Sabrina Daehling, Stephan Becker, Birgit Gathof, Christoph Kreer, Manuel Koch, Henning Gruell, Kanika Vanshylla, Matthias Zehner, Sandro Halwe, Susanne Detmer, Lutz Gieselmann, Florian Klein, Michael Kluever, Maike Schlotz, Johanna Worczinski
SummaryPre-existing immunity against SARS-CoV-2 may have critical implications for our understanding of COVID-19 susceptibility and severity. Various studies recently provided evidence of pre-existing T cell immunity against SARS-CoV-2 in unexposed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f7da87a1812c85c040344198d53507d
https://doi.org/10.1101/2021.09.08.459398
https://doi.org/10.1101/2021.09.08.459398
Autor:
Timm Weber, Julian Potthoff, Sven Bizu, Maurice Labuhn, Leona Dold, Till Schoofs, Marcel Horning, Meryem S. Ercanoglu, Christoph Kreer, Lutz Gieselmann, Kanika Vanshylla, Bettina Langhans, Hanna Janicki, Luisa J. Ströh, Elena Knops, Dirk Nierhoff, Ulrich Spengler, Rolf Kaiser, Pamela J. Bjorkman, Thomas Krey, Dorothea Bankwitz, Nico Pfeifer, Thomas Pietschmann, Andrew I. Flyak, Florian Klein
Publikováno v:
Immunity
The high genetic diversity of hepatitis C virus (HCV) complicates effective vaccine development. We screened a cohort of 435 HCV-infected individuals and found that 2%–5% demonstrated outstanding HCV-neutralizing activity. From four of these patien
Autor:
Lutz Gieselmann, Artem Ashurov, Cornelius Rohde, Sandro Halwe, Veronica Di Cristanziano, Stephan Becker, Alexandra Kupke, Nico Pfeifer, Manuel Koch, Simone Lederer, Timo Wolf, Ron Diskin, Hadas Cohen-Dvashi, Kanika Vanshylla, Philipp Schommers, Maria J G T Vehreschild, Matthias Zehner, M. Korenkov, Clemens M. Wendtner, Reinhild Brinker, Christoph Kreer, Timm Weber, Florian Klein, Meryem S. Ercanoglu, Hanna Janicki, Verena Krähling, Henning Gruell
SUMMARYThe SARS-CoV-2 pandemic has unprecedented implications for public health, social life, and world economy. Since approved drugs and vaccines are not available, new options for COVID-19 treatment and prevention are highly demanded. To identify S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120b7fa1bed6ee58911579e058db3d92
https://publica.fraunhofer.de/handle/publica/267007
https://publica.fraunhofer.de/handle/publica/267007
Autor:
Robert C. Münch, Anke Rasbach, Hanna Janicki, Iris Völker, Michael Hallek, Christian J. Buchholz, Hildegard Büning
Publikováno v:
Molecular Therapy. 21:109-118
Gene transfer vectors derived from the adeno-associated virus (AAV) have recently received increasing attention due to substantial therapeutic benefit in several clinical trials. Nevertheless, their great potential for in vivo gene therapy can only b