Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hanna Grobe"'
Autor:
Estibaliz Gómez-de-Mariscal, Hanna Grobe, Joanna W Pylvänäinen, Laura Xénard, Ricardo Henriques, Jean-Yves Tinevez, Guillaume Jacquemet
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002740 (2024)
In life sciences, tracking objects from movies enables researchers to quantify the behavior of single particles, organelles, bacteria, cells, and even whole animals. While numerous tools now allow automated tracking from video, a significant challeng
Externí odkaz:
https://doaj.org/article/50ab8682fe95494880f7a166e182d85b
Autor:
Gali Epstein Shochet, Elizabetha Brook, Becky Bardenstein-Wald, Hanna Grobe, Evgeny Edelstein, Lilach Israeli-Shani, David Shitrit
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 11 (2020)
Background and objective: The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerate
Externí odkaz:
https://doaj.org/article/26b9eaac590a4e77a43a0b9f2b3d6218
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194716 (2018)
De novo formation of epithelial cell-cell contacts relies on actin-based protrusions as well as tightly controlled turnover of junctional actin once cells encounter each other and adhesion complexes assemble. The specific contributions of individual
Externí odkaz:
https://doaj.org/article/837d6e6cf55c4db3a083e76596c80c44
Autor:
Sushmita Chatterjee, Gonna Somu Naidu, Inbal Hazan-Halevy, Hanna Grobe, Assaf Ezra, Preeti Sharma, Meir Goldsmith, Srinivas Ramishetti, David Sprinzak, Ronen Zaidel-Bar, Dan Peer
Publikováno v:
Science Advances. 9
The potential of microtubule-associated protein targets for cancer therapeutics remains largely unexplored due to the lack of target-specific agents. Here, we explored the therapeutic potential of targeting cytoskeleton-associated protein 5 (CKAP5),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69bf0cc7299dd16cf48da0dd90387f4
https://doi.org/10.1126/sciadv.ade4800
https://doi.org/10.1126/sciadv.ade4800
Autor:
Sushmita Chatterjee, Gonna Somu Naidu, Inbal Hazan-Halevy, Hanna Grobe, Assaf Ezra, Srinivas Ramishetti, David Sprinzak, Ronen Zaidel-Bar, Dan Peer
Cell mitosis is an attractive target for cancer therapy. Presently, anti-mitotic drugs are limited to tubulin binding agents and kinase inhibitors. While there is a long list of potential microtubule associated protein targets that play an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1033950c8050972a2f22b41baf1070f4
https://doi.org/10.21203/rs.3.rs-1898494/v1
https://doi.org/10.21203/rs.3.rs-1898494/v1
Autor:
Ronen Zaidel-Bar, Nikola Lukic, Jonathan Solomon, Hanna Grobe, Tal Sneh, Stefanie Lapetina, Hava Gil-Henn, Shams Twafra, Michal Gendler, Kolluru D. Srikanth
Publikováno v:
Molecular Biology of the Cell
Focal adhesion kinase (FAK) is well established as a regulator of cell migration, but whether and how the closely related proline-rich tyrosine kinase 2 (Pyk2) regulates fibroblast motility is still under debate. Using mouse embryonic fibroblasts (ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d24190788465ae5e34a37be08a9edb
https://doi.org/10.1091/mbc.e20-10-0640
https://doi.org/10.1091/mbc.e20-10-0640
Autor:
Hagar, Mor-Shaked, Emuna, Paz-Ebstein, Adily, Basal, Simona, Ben-Haim, Hanna, Grobe, Sami, Heymann, Zvi, Israel, Montaser, Namnah, Anat, Nitzan, Chaggai, Rosenbluh, Ann, Saada, Tomer, Tzur, Shira, Yanovsky-Dagan, Ronen, Zaidel-Bar, Tamar, Harel, David, Arkadir
Publikováno v:
Brain Communications
Biallelic pathogenic variants in PRKN (PARK2), encoding the E3 ubiquitin ligase parkin, lead to early-onset Parkinson's disease. Structural variants, including duplications or deletions, are common in PRKN due to their location within the fragile sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc1c37306f10b777463fd02c6792a8e7
https://pubmed.ncbi.nlm.nih.gov/34514401
https://pubmed.ncbi.nlm.nih.gov/34514401
Autor:
Tomer Tzur, Hanna Grobe, Anat Nitzan, Chaggai Rosenbluh, Sami Heymann, Emuna Paz-Ebstein, David Arkadir, Hagar Mor-Shaked, Tamar Harel, Simona Ben-Haim, Adily Basal, Zvi Israel, Shira Yanovsky-Dagan, Ann Saada, Montaser Namnah, Ronen Zaidel-Bar
Publikováno v:
Brain Communications. 3
Biallelic pathogenic variants in PRKN (PARK2), encoding the E3 ubiquitin ligase parkin, lead to early-onset Parkinson's disease. Structural variants, including duplications or deletions, are common in PRKN due to their location within the fragile sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f864557beea6a3d156bc7392f53be1
https://doi.org/10.1093/braincomms/fcab197
https://doi.org/10.1093/braincomms/fcab197
Autor:
Ronen Zaidel-Bar, Chen Luxenburg, Orit Adir, Hanna Grobe, Jonathan Cohen, Adnan Mahly, Krishnanand Padmanabhan, Arad Soffer
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Planar cell polarity (PCP) is essential for tissue morphogenesis and homeostasis; however, the mechanisms that orchestrate the cell shape and packing dynamics required to establish PCP are poorly understood. Here, we identified a major role for the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339be23563d6cb4055679eba0ad0aaea
https://doi.org/10.1242/dev.193425
https://doi.org/10.1242/dev.193425
Autor:
Hanna Grobe, Elizabetha Brook, Gali Epstein Shochet, Becky Bardenstein-Wald, Evgeny Edelstein, David Shitrit, Lilach Israeli-Shani
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 11 (2020)
Therapeutic Advances in Chronic Disease
Therapeutic Advances in Chronic Disease
Background and objective:The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d685f21ef675480124d36859a5249f
https://doaj.org/article/26b9eaac590a4e77a43a0b9f2b3d6218
https://doaj.org/article/26b9eaac590a4e77a43a0b9f2b3d6218