Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hanna Englert"'
Autor:
Hanna Englert, Josephine Göbel, Danika Khong, Maryam Omidi, Nina Wolska, Sandra Konrath, Maike Frye, Reiner K. Mailer, Manu Beerens, Julian C. Gerwers, Roger J. S. Preston, Jacob Odeberg, Lynn M. Butler, Coen Maas, Evi X. Stavrou, Tobias A. Fuchs, Thomas Renné
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundNeutrophil Extracellular Traps (NETs) are key mediators of immunothrombotic mechanisms and defective clearance of NETs from the circulation underlies an array of thrombotic, inflammatory, infectious, and autoimmune diseases. Efficient NET d
Externí odkaz:
https://doaj.org/article/9aed362b20df48998e4383fc4e6df556
Autor:
Sandra Konrath, Reiner K. Mailer, Manu Beerens, Hanna Englert, Maike Frye, Piotr Kuta, Roger J. S. Preston, Coen Maas, Lynn M. Butler, Mark Roest, Bas de Laat, Thomas Renné
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Calibrated Automated Thrombography (CAT) is a versatile and sensitive method for analyzing coagulation reactions culminating in thrombin generation (TG). Here, we present a CAT method for analyzing TG in murine whole blood by adapting the CAT assay u
Externí odkaz:
https://doaj.org/article/ea917332e07143deb5c08fe5ee31705f
Autor:
Hanna Englert, Chandini Rangaswamy, Carsten Deppermann, Jan-Peter Sperhake, Christoph Krisp, Danny Schreier, Emma Gordon, Sandra Konrath, Munif Haddad, Giordano Pula, Reiner K. Mailer, Hartmut Schlüter, Stefan Kluge, Florian Langer, Klaus Püschel, Kosta Panousis, Evi X. Stavrou, Coen Maas, Thomas Renné, Maike Frye
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103382- (2021)
Background: Coagulopathy and inflammation are hallmarks of Coronavirus disease 2019 (COVID-19) and are associated with increased mortality. Clinical and experimental data have revealed a role for neutrophil extracellular traps (NETs) in COVID-19 dise
Externí odkaz:
https://doaj.org/article/f07dda3a7eaf4a2991a79c421ec628e9
Autor:
Thomas Renné, Abhishek Upadhyay, Hanna Englert, Mareike G. Posner, Ian M. Eggleston, Stuart Wallis, Stefan Bagby, Giordano Pula, Nina Wolska
Publikováno v:
Wallis, S, Wolska, N, Englert, H, Posner, M, Upadhyay, A, Renne, T, Eggleston, I, Bagby, S & Pula, G 2022, ' A peptide from the staphylococcal protein Efb binds P-selectin and inhibits the interaction of platelets with leukocytes ', Journal of Thrombosis and Haemostasis, vol. 20, no. 3, pp. 729-741 . https://doi.org/10.1111/jth.15613, https://doi.org/10.1111/jth.15613
AimsP-selectin is a key surface adhesion molecule for the interaction of platelets with leukocytes. We have shown previously that the N-terminal domain of S. aureus extracellular fibrinogen-binding protein (Efb) binds to P-selectin and interferes wit
Autor:
Bastian F. J. Plochg, Hanna Englert, Chandini Rangaswamy, Sandra Konrath, Mandy Malle, Sibylle Lampalzer, Claudia Beisel, Salma Wollin, Maike Frye, Jens Aberle, Johannes Kluwe, Thomas Renné, Reiner K. Mailer
Publikováno v:
Journal of Internal Medicine. 291:648-664
Liver-derived apolipoprotein B-100 (ApoB100) is an autoantigen that is recognized by atherogenic CD4We identified ApoB100-specific T cells in blood from healthy controls, nonalcoholic fatty liver disease (NAFLD) patients, and CVD patients by activati
Autor:
Andreas Büttner, Michael Lalk, Raghavendra Palankar, Stefan Kochanek, Reiner K. Mailer, Evi X. Stavrou, Uwe Völker, Karen Methling, Thomas Renné, Konstanze Aurich, Leif Steil, Thomas Thiele, Lea Krutzke, Martin Beer, Maike Frye, Kathleen Selleng, Theodore E. Warkentin, Chandini Rangaswamy, Hanna Englert, Martina Wolff, Stephan Michalik, Linda Schönborn, Nicole Endlich, Florian Siegerist, Alexander Reder, Boris Fehse, Christian Hentschker, Jan Wesche, Stefan Handtke, Andreas Greinacher, Kati Franzke
Publikováno v:
Blood
SARS-CoV-2 vaccine ChAdOx1 nCoV-19 (AstraZeneca) causes a thromboembolic complication termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Using biophysical techniques, mouse models, and analysis of VITT patient samples, we identified de
Autor:
Sandra, Konrath, Reiner K, Mailer, Manu, Beerens, Hanna, Englert, Maike, Frye, Piotr, Kuta, Roger J S, Preston, Coen, Maas, Lynn M, Butler, Mark, Roest, Bas, de Laat, Thomas, Renné
Calibrated Automated Thrombography (CAT) is a versatile and sensitive method for analyzing coagulation reactions culminating in thrombin generation (TG). Here, we present a CAT method for analyzing TG in murine whole blood by adapting the CAT assay u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57460af8d35aa8bf0c962738172c2ee1
https://hdl.handle.net/10037/28126
https://hdl.handle.net/10037/28126
Autor:
Helen Fogarty, Liam Townsend, Hannah Morrin, Azaz Ahmad, Claire Comerford, Ellie Karampini, Hanna Englert, Mary Byrne, Colm Bergin, Jamie M. O’Sullivan, Ignacio Martin‐Loeches, Parthiban Nadarajan, Ciaran Bannan, Patrick W. Mallon, Gerard F. Curley, Roger J.S. Preston, Aisling M. Rehill, Dennis McGonagle, Cliona Ni Cheallaigh, Ross I. Baker, Thomas Renné, Soracha E. Ward, James S. O’Donnell, Niamh O’Connell, Kevin Ryan, Dermot Kenny, Judicael Fazavana
Publikováno v:
Journal of Thrombosis and Haemostasis
Background Persistent symptoms including breathlessness, fatigue, and decreased exercise tolerance have been reported in patients after acute SARS-CoV-2 infection. The biological mechanisms underlying this “long COVID” syndrome remain unknown. Ho
Publikováno v:
Seminars in Immunopathology
Coagulation is controlled by a delicate balance of prothrombotic and antithrombotic mechanisms, to prevent both excessive blood loss from injured vessels and pathologic thrombosis. The liver plays a pivotal role in hemostasis through the synthesis of
Polyanions in Coagulation and Thrombosis: Focus on Polyphosphate and Neutrophils Extracellular Traps
Publikováno v:
Thrombosis and Haemostasis. 121:1021-1030
Neutrophil extracellular traps (NETs) and polyphosphates (polyP) have been recognized as procoagulant polyanions. This review summarizes the activities and regulation of the two procoagulant mediators and compares their functions. NETs are composed o