Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Hanna Dams-Kozlowska"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Bioengineered MS1 silk is derived from major ampullate spidroin 1 (MaSp1) from the spider Nephila clavipes. The MS1 silk was functionalized with the H2.1 peptide to target Her2-overexpressing cancer cells. The immunogenic potential of drug c
Externí odkaz:
https://doaj.org/article/2f712504bb9148eab3c4a1462a5f7305
Autor:
Anna Florczak, Tomasz Deptuch, Anna Lewandowska, Karolina Penderecka, Elzbieta Kramer, Andrzej Marszalek, Andrzej Mackiewicz, Hanna Dams-Kozlowska
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background Chemotherapy is often a first-line therapeutic approach for the treatment of a wide variety of cancers. Targeted drug delivery systems (DDSs) can potentially resolve the problem of chemotherapeutic drug off-targeting effects. Here
Externí odkaz:
https://doaj.org/article/be9d9eccb1114c1aa7bdd12d8ac8e89b
Autor:
Kamil Kucharczyk, Anna Florczak, Tomasz Deptuch, Karolina Penderecka, Katarzyna Jastrzebska, Andrzej Mackiewicz, Hanna Dams-Kozlowska
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background The optimal drug delivery system should be biocompatible, biodegradable, and allow the sustained release of the drug only after it reaches the target cells. Silk, as a natural polymer, is a great candidate for building drug carrie
Externí odkaz:
https://doaj.org/article/f3343c19a3324058af5913b3b564aa2a
Autor:
Kamil Kucharczyk, Jakub Dalibor Rybka, Michael Hilgendorff, Michal Krupinski, Mariusz Slachcinski, Andrzej Mackiewicz, Michael Giersig, Hanna Dams-Kozlowska
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219790 (2019)
Bioengineered spider silk is a biomaterial that has exquisite mechanical properties, biocompatibility, and biodegradability. Iron oxide nanoparticles can be applied for the detection and analysis of biomolecules, target drug delivery, as MRI contrast
Externí odkaz:
https://doaj.org/article/cca381bdf8e54be984488e93cf1b4813
Autor:
Hanna Dams-Kozlowska, Eliza Kwiatkowska-Borowczyk, Katarzyna Gryska, Anna Lewandowska, Andrzej Marszalek, Sebastian Adamczyk, Anna Kowalik, Ewa Leporowska, Andrzej Mackiewicz
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154520 (2016)
The incidence of cancer is constantly increasing. Chemo/radiotherapy is one of major methods of treating cancer. Although adverse chemo/radiotherapy events, such as anemia and neutropenia, can be successfully cured, thrombocytopenia is still problema
Externí odkaz:
https://doaj.org/article/4a597c8054f245a4ad449431d7e721af
Autor:
Andrzej Mackiewicz, Andrzej Marszałek, Karolina Penderecka, Hanna Dams-Kozlowska, Anna Florczak, Tomasz Deptuch, Ewa Leporowska, Anna Lewandowska
Publikováno v:
Nanomedicine. 16:1553-1565
Background: Due to factors such as silk sequence, purification, degradation, morphology and functionalization, each silk variant should be individually tested for potential toxicity. Aim: In vivo toxicological evaluation of the previously characteriz
Publikováno v:
International Journal of Nanomedicine. 14:6855-6865
Background The development of nanocarrier technology has attracted great interest in the last decade. Biodegradable spheres made of functionalized silk have considerable potential to be used as drug delivery systems for cancer treatment. A targeting
Autor:
Tomasz, Deptuch, Anna, Florczak, Anna, Lewandowska, Ewa, Leporowska, Karolina, Penderecka, Andrzej, Marszalek, Andrzej, Mackiewicz, Hanna, Dams-Kozlowska
Publikováno v:
Nanomedicine (London, England). 16(18)
Autor:
Hanna Dams-Kozlowska, Andrzej Mackiewicz, Kosma Sakrajda, Agata Golabek, Mariusz Kaczmarek, Ewelina Dondajewska
Publikováno v:
Experimental and Therapeutic Medicine
Knowledge of the tumor microenvironment is crucial for developing an effective strategy to treat cancer. Recently, anticancer therapies targeting macrophages have been intensively investigated. Increased understanding of the importance of the tumor m
Autor:
Anna Florczak, Alicja Kaminska, Inga Grzechowiak, Tomasz Deptuch, Kamil Kucharczyk, Hanna Dams-Kozlowska
Publikováno v:
Materials
Materials, Vol 13, Iss 4946, p 4946 (2020)
Materials, Vol 13, Iss 4946, p 4946 (2020)
Although progress is observed in cancer treatment, this disease continues to be the second leading cause of death worldwide. The current understanding of cancer indicates that treating cancer should not be limited to killing cancer cells alone, but t