Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hanna A Zielinska"'
Publikováno v:
Cells, Vol 11, Iss 1, p 94 (2021)
Cholesterol—in particular, high levels of low-density lipoprotein (LDL) and its metabolite, 27-hydroxycholesterol (27-OHC)—is correlated with increases in the risks of breast cancer and obesity. Although the high expression of LDL/27-OHC has been
Externí odkaz:
https://doaj.org/article/e99b649aeebc4baaa8d426a6513f9d28
Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients
Autor:
Ahmad Al-Ghamdi, Carl S Daly, Jeffrey M P Holly, Paul D. White, Hanna A Zielinska, Claire M Perks, Muhammed Sohail, Sarah R Dean, Amit Bahl
Publikováno v:
Cancers
Volume 12
Issue 12
Cancers, Vol 12, Iss 3821, p 3821 (2020)
Zielinska, H A, Daly, C S, Alghamdi, A, Bahl, A, Sohail, M, White, P, Dean, S R, Holly, J M P & Perks, C M 2020, ' Interaction between GRP78 and IGFBP-3 affects tumorigenesis and prognosis in breast cancer patients ', Cancers, vol. 12, no. 12, 3821 . https://doi.org/10.3390/cancers12123821
Volume 12
Issue 12
Cancers, Vol 12, Iss 3821, p 3821 (2020)
Zielinska, H A, Daly, C S, Alghamdi, A, Bahl, A, Sohail, M, White, P, Dean, S R, Holly, J M P & Perks, C M 2020, ' Interaction between GRP78 and IGFBP-3 affects tumorigenesis and prognosis in breast cancer patients ', Cancers, vol. 12, no. 12, 3821 . https://doi.org/10.3390/cancers12123821
Insulin-like growth factor binding protein 3 (IGFBP-3) plays a key role in breast cancer progression and was recently shown to bind to the chaperone protein glucose-regulated protein 78 (GRP78)
however, the clinical significance of this associat
however, the clinical significance of this associat
Autor:
Rehanna Mansor, Jeffrey M P Holly, Edward Rowe, Claire M Perks, Rachel Barker, Hanna A Zielinska, Alex Sewell, J. Athene Lane, Kalina Biernacka, Lucy Hackshaw-McGeagh, Jon Oxley, Anthony Koupparis, Richard M. Martin
Publikováno v:
Mansor, R, Holly, J M P, Barker, R M, Biernacka, K M, Zielinska, H A, Koupparis, A J, Rowe, E, Oxley, J, Sewell, A, Martin, R M, Lane, J A, Hackshaw-McGeagh, L & Perks, C M 2020, ' IGF-1 and Hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells ', Oncotarget, vol. 11, pp. 2543-2559 . https://doi.org/10.18632/oncotarget.27650
Oncotarget
Oncotarget
Localized prostate cancer (PCa) is a manageable disease but for most men with metastatic disease, it is often fatal. A western diet has been linked with PCa progression and hyperglycaemia has been associated with the risk of lethal and fatal prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4dcefba682fe27816ed369e344712e
https://research-information.bris.ac.uk/ws/files/248916103/27650_1056348_1_PB.pdf
https://research-information.bris.ac.uk/ws/files/248916103/27650_1056348_1_PB.pdf
Autor:
Bridget A. Knight, Nuno L. Barbosa-Morais, Mads Daugaard, Hanna A Zielinska, Ingrid Ehrmann, John J. McGrath, Oliver Thompson, Sebastian Oltean, Ling Li, Jennifer Munkley, Simon Cockell, Htoo Zarni Oo, Gerald Hysenaj, Lorna W. Harries, Kathleen Cheung, Emma Scott, David J. Elliott, Caroline Dalgliesh, Teresa Mendes Maia, S R Gokul Krishnan, Paul McCullagh, Karen E. Livermore, Malcolm Crundwell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c7d604f75a67bdac52cf6fde502c762
https://doi.org/10.7554/elife.47678.028
https://doi.org/10.7554/elife.47678.028
Autor:
Paul McCullagh, Emma Scott, David J. Elliott, Mads Daugaard, Oliver Thompson, John A. McGrath, Jennifer Munkley, Htoo Zarni Oo, Simon Cockell, Lorna W. Harries, Kathleen Cheung, Bridget A. Knight, Sebastian Oltean, Nuno L. Barbosa-Morais, Hanna A Zielinska, Karen E. Livermore, Gerald Hysenaj, Ingrid Ehrmann, Malcolm Crundwell, Teresa Mendes Maia, S R Gokul Krishnan, Ling Li
Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen receptor (AR) activity, yet al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0321ab6dd9c41d6bec34a9670e96dd88
https://doi.org/10.1101/629618
https://doi.org/10.1101/629618
Autor:
Jennifer Munkley, Sebastian Oltean, Caroline Dalgliesh, Gerald Hysenaj, Nuno L. Barbosa-Morais, Hanna A Zielinska, Teresa Mendes Maia, S R Gokul Krishnan, Paul McCullagh, Bridget A. Knight, Htoo Zarni Oo, Oliver Thompson, Lorna W. Harries, Ling Li, Ingrid Ehrmann, Simon Cockell, Karen E. Livermore, Kathleen Cheung, Mads Daugaard, John A. McGrath, Emma Scott, David J. Elliott, Malcolm Crundwell
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Cancers often begin as cells that grow in connected sheets or clumps known as epithelial cells. To spread, the cancer cells need to change into cells that can break away from the group and move through the tissues. In prostate cancer, this process ca
Publikováno v:
Breast Cancer : Targets and Therapy
Evidence indicates that for most human cancers the problem is not that gene mutations occur but is more dependent upon how the body deals with damaged cells. It has been estimated that only about 1% of human cancers can be accounted for by unmistakab
Autor:
Jeffrey M P Holly, Claire M Perks, Azeem Arshad, Amit Bahl, Hanna A Zielinska, Julian P.H. Shield, Li Zeng
Publikováno v:
Zeng, L, Zielinska, H A, Arshad, A, Hamilton-Shield, J P, Bahl, A, Holly, J M P & Perks, C M 2016, ' Hyperglycaemia-induced chemo-resistance in breast cancer cells : role of the estrogen receptor ', Endocrine-Related Cancer, vol. 23, no. 2, pp. 125-134 . https://doi.org/10.1530/ERC-15-0507
Breast cancer patients with diabetes respond less well to chemotherapy; in keeping with this we determined previously that hyperglycaemia induced chemo-resistance in estrogen receptor (ERα) positive breast cancer cells and showed that this was media
Publikováno v:
Cancer Research. 77:P6-02
This abstract was withdrawn by the authors.