Výsledky vyhledávání - "Hanna, Courtney"

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Dissertation/ Thesis

Recurrent miscarriage : unraveling the complex etiology

Autor: Hanna, Courtney Wood

Recurrent miscarriage (RM), defined as 3 or more consecutive spontaneous losses of pregnancy before 20 weeks gestation, affects 1-2% of couples and has a complex etiology. Half of miscarriages from RM cases are caused by chromosomal abnormalities in

Externí odkaz: http://hdl.handle.net/2429/44347

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Akademický článek

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Primitive haematopoiesis in the human placenta gives rise to macrophages with epigenetically silenced HLA-DR

Autor: Thomas, Jake R, Appios, Anna, Calderbank, Emily F, Yoshida, Nagisa, Zhao, Xiaohui, Hamilton, Russell S, Moffett, Ashley, Sharkey, Andrew, Laurenti, Elisa, Hanna, Courtney W, McGovern, Naomi

The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. Although this process is thought to be spatially restricted to the yolk sac in the mouse, in humans, it remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e9439bd69de08cabd07d191e342cb7
https://www.repository.cam.ac.uk/handle/1810/348156

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Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B

Autor: Hanna, Courtney

DNA methylation is a repressive epigenetic modification that is essential for development, exemplified by the embryonic and perinatal lethality observed in mice lacking de novo DNA methyltransferases (DNMTs). Here we characterise the role for DNMT3A,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10823d227be2ba03d1bfc46ca205184f

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