Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hann Low"'
Autor:
Ryunosuke Ohkawa, Hann Low, Nigora Mukhamedova, Ying Fu, Shao-Jui Lai, Mai Sasaoka, Ayuko Hara, Azusa Yamazaki, Takahiro Kameda, Yuna Horiuchi, Peter J. Meikle, Gerard Pernes, Graeme Lancaster, Michael Ditiatkovski, Paul Nestel, Boris Vaisman, Denis Sviridov, Andrew Murphy, Alan T. Remaley, Dmitri Sviridov, Minoru Tozuka
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Externí odkaz:
https://doaj.org/article/c85e2bd927424090baf6850db15b6a1c
Publikováno v:
Bio-Protocol, Vol 10, Iss 13 (2020)
Lipid rafts are distinct liquid-ordered domains of plasma membranes of most eukaryotic cells providing platform for signaling pathways. Lipid composition of rafts is critical for their structural integrity and for regulation of signaling pathways ori
Externí odkaz:
https://doaj.org/article/b5afb4fee6d04fec885f0a968b2906e7
Autor:
Silvana Di Yacovo, Maria Saumoy, José Luís Sánchez-Quesada, Antonio Navarro, Dmitri Sviridov, Manuel Javaloyas, Ramon Vila, Anton Vernet, Hann Low, Judith Peñafiel, Benito García, Jordi Ordoñez-Llanos, Daniel Podzamczer
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237739 (2020)
ObjectiveTo assess the effect of HIV infection and combined antiretroviral therapy (c-ART) on various proatherogenic biomarkers and lipids and to investigate their relationship with subclinical atherosclerosis in a cohort of treatment-naive HIV-infec
Externí odkaz:
https://doaj.org/article/01c0f7a1f1594b7b929ba67169cd5166
Autor:
Sarah A. Woller, Soo-Ho Choi, Eun Jung An, Hann Low, Dina A. Schneider, Roshni Ramachandran, Jungsu Kim, Yun Soo Bae, Dmitri Sviridov, Maripat Corr, Tony L. Yaksh, Yury I. Miller
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2667-2677 (2018)
Apolipoprotein A-I binding protein (AIBP) reduces lipid raft abundance by augmenting the removal of excess cholesterol from the plasma membrane. Here, we report that AIBP prevents and reverses processes associated with neuroinflammatory-mediated spin
Externí odkaz:
https://doaj.org/article/752f1381fb2546bd8b718014a285dc72
Autor:
Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J Meikle, Anelia Horvath, Beda Brichacek, Yury I Miller, Andrew Murphy, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007907 (2019)
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors. Here we show that exosomes containing HIV-1 protein Nef (exNef) a
Externí odkaz:
https://doaj.org/article/e9e4d551c4234d93af6f7c00d4033bd0
Autor:
Hann Low, Anh Hoang, Tatiana Pushkarsky, Larisa Dubrovsky, Elizabeth Dewar, Maria-Silvana Di Yacovo, Nigora Mukhamedova, Lesley Cheng, Catherine Downs, Gary Simon, Maria Saumoy, Andrew F Hill, Michael L Fitzgerald, Paul Nestel, Anthony Dart, Jennifer Hoy, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215620 (2019)
HIV infection is known to be associated with cardiometabolic abnormalities; here we investigated the progression and causes of these abnormalities. Three groups of participants were recruited: HIV-negative subjects and two groups of treatment-naïve
Externí odkaz:
https://doaj.org/article/8a36007eecad4ae2b822de4fdc5bccc8
Autor:
Hann Low, Nigora Mukhamedova, Huanhuan L. Cui, Brian P. McSharry, Selmir Avdic, Anh Hoang, Michael Ditiatkovski, Yingying Liu, Ying Fu, Peter J. Meikle, Martin Blomberg, Konstantinos A. Polyzos, William E. Miller, Piotr Religa, Michael Bukrinsky, Cecilia Soderberg-Naucler, Barry Slobedman, Dmitri Sviridov
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 186-200 (2016)
Cytomegalovirus (HCMV) contains cholesterol, but how HCMV interacts with host cholesterol metabolism is unknown. We found that, in human fibroblasts, HCMV infection increased the efflux of cellular cholesterol, despite reducing the abundance of ABCA1
Externí odkaz:
https://doaj.org/article/3e8942e781bd49fe8b389bb8108a2d62
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 168-175 (2016)
Previous in vitro and in vivo studies demonstrated that HIV protein nef plays a key role in impairing cellular and systemic cholesterol metabolism in HIV disease, but clinical support for these findings is lacking. Here we present the data of compara
Externí odkaz:
https://doaj.org/article/559c39a09d1c4441a9a0073b78bf200a
Autor:
Graeme I. Lancaster, Denis Sviridov, Nigora Mukhamedova, Takahiro Kameda, Gerard Pernes, Peter J. Meikle, Ryunosuke Ohkawa, Boris L. Vaisman, Andrew J. Murphy, Ayuko Hara, Ying Fu, Michael Ditiatkovski, Shao-Jui Lai, Paul J. Nestel, Alan T. Remaley, Hann Low, Dmitri Sviridov, Minoru Tozuka, Yuna Horiuchi, Mai Sasaoka, Azusa Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
J Lipid Res
J Lipid Res
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Autor:
Michael Bukrinsky, Nigora Mukhamedova, Seth J. Field, Michael Ditiatkovski, Peter J. Meikle, Soo-Ho Choi, Kevin Huynh, Hann Low, Ryunosuke Ohkawa, Luciano Dos Santos Aggum Capettini, Yury I. Miller, Yining Xia, Dmitri Sviridov, Stephen H. Cody, Irena Carmichael
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: AIBP (apolipoprotein A-I binding protein) is an effective and selective regulator of lipid rafts modulating many metabolic pathways originating from the rafts, including inflammation. The mechanism of action was suggested to involve stimul