Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Hanné Andersen"'
Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
Autor:
Matthew Gagne, Barbara J. Flynn, Christopher Cole Honeycutt, Dillon R. Flebbe, Shayne F. Andrew, Samantha J. Provost, Lauren McCormick, Alex Van Ry, Elizabeth McCarthy, John-Paul M. Todd, Saran Bao, I-Ting Teng, Shir Marciano, Yinon Rudich, Chunlin Li, Shilpi Jain, Bushra Wali, Laurent Pessaint, Alan Dodson, Anthony Cook, Mark G. Lewis, Hanne Andersen, Jiří Zahradník, Mehul S. Suthar, Martha C. Nason, Kathryn E. Foulds, Peter D. Kwong, Mario Roederer, Gideon Schreiber, Robert A. Seder, Daniel C. Douek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract SARS-CoV-2 has the capacity to evolve mutations that escape vaccine- and infection-acquired immunity and antiviral drugs. A variant-agnostic therapeutic agent that protects against severe disease without putting selective pressure on the vir
Externí odkaz:
https://doaj.org/article/398a2dfd9ac6483f881f1a81f6f17840
Autor:
Caitlin A. Williams, Teri Ann S. Wong, Michael M. Lieberman, Jake Yalley-Ogunro, Mehtap Cabus, Sara Nezami, Fabian Paz, Hanne Andersen, Thomas W. Geisbert, Axel T. Lehrer
Publikováno v:
Immuno, Vol 3, Iss 4, Pp 358-374 (2023)
Zaire ebolavirus (EBOV) poses a significant threat to public health due to its high case fatality rate and epidemic potential. This is further complicated by the lack of precise immune correlates of protection and difficulties in conducting in vivo a
Externí odkaz:
https://doaj.org/article/631254b4c4b2469ebf294d9f72648198
Autor:
Catherine Jacob-Dolan, Jingyou Yu, Katherine McMahan, Victoria Giffin, Abishek Chandrashekar, Amanda J. Martinot, Tochi Anioke, Olivia C. Powers, Kevin Hall, David Hope, Jessica Miller, Nichole P. Hachmann, Benjamin Chung, Sarah Gardner, Daniel Sellers, Julia Barrett, Mark G. Lewis, Hanne Andersen, Harry Kleanthous, Ki-Woen Seo, Su Jeen Lee, Yong Wook Park, Hun Kim, Dan H. Barouch
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Despite the availability of several effective SARS-CoV-2 vaccines, additional vaccines will be required for optimal global vaccination. In this study, we investigate the immunogenicity and protective efficacy of the GBP510 protein subunit va
Externí odkaz:
https://doaj.org/article/2859911f0f034613a627935fa3b765b4
Autor:
Yongjun Sui, Hanne Andersen, Jianping Li, Tanya Hoang, Yonas Bekele, Swagata Kar, Mark G. Lewis, Jay A. Berzofsky
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAdjuvant plays an important role in directing the immune responses induced by vaccines. In previous studies, we have shown that a mucosal SARS-CoV-2 S1 subunit vaccine adjuvanted with a combination of CpG, Poly I:C and IL-15 (named CP15)
Externí odkaz:
https://doaj.org/article/8dd1479024234e54afb4666e3c0b1c9c
Autor:
Felix Wussow, Mindy Kha, Katelyn Faircloth, Vu H. Nguyen, Angelina Iniguez, Joy Martinez, Yoonsuh Park, Jenny Nguyen, Swagata Kar, Hanne Andersen, Mark G. Lewis, Flavia Chiuppesi, Don J. Diamond
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104457- (2022)
Summary: COVID-19 vaccine efficacy is threatened by emerging SARS-CoV-2 variants of concern (VOC) with the capacity to evade protective neutralizing antibody responses. We recently developed clinical vaccine candidate COH04S1, a synthetic modified va
Externí odkaz:
https://doaj.org/article/a76f6bba437449628feb349c980b165d
Autor:
Moonsup Jeong, Sagar B. Kudchodkar, Areum Gil, Bohyun Jeon, Gee Ho Park, Youngran Cho, Hyojin Lee, Mi Sun Cheong, Wonil Kim, Yun-Ho Hwang, Jung-Ah Lee, Heeji Lim, Mi Young Kim, Emran O. Lallow, Tej Brahmbhatt, Stephen A. Kania, Nandita C. Jhumur, Jerry W. Shan, Jeffrey D. Zahn, David I. Shreiber, Jonathan P. Singer, Hao Lin, Erin K. Spiegel, Laurent Pessaint, Maciel Porto, Alex Van Ry, Danielle Nase, Swagata Kar, Hanne Andersen, Ian Tietjen, Joel Cassel, Joseph M. Salvino, Luis J. Montaner, Young K. Park, Kar Muthumani, Christine C. Roberts, Joel N. Maslow
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
SARS-CoV-2 is the third pathogenic coronavirus to emerge since 2000. Experience from prior outbreaks of SARS-CoV and MERS-CoV has demonstrated the importance of both humoral and cellular immunity to clinical outcome, precepts that have been recapitul
Externí odkaz:
https://doaj.org/article/c73deb36ca654fa2815416d4cd1e4dd1
Autor:
Daniel Y Zhu, Matthew J Gorman, Dansu Yuan, Jingyou Yu, Noe B Mercado, Katherine McMahan, Erica N Borducchi, Michelle Lifton, Jinyan Liu, Felix Nampanya, Shivani Patel, Lauren Peter, Lisa H Tostanoski, Laurent Pessaint, Alex Van Ry, Brad Finneyfrock, Jason Velasco, Elyse Teow, Renita Brown, Anthony Cook, Hanne Andersen, Mark G Lewis, Douglas A Lauffenburger, Dan H Barouch, Galit Alter
Publikováno v:
PLoS Biology, Vol 20, Iss 5, p e3001609 (2022)
Despite the rapid creation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccines, the precise correlates of immunity against severe Coronavirus Disease 2019 (COVID-19) are still unknown. Neutralizing antibodies represent a robust s
Externí odkaz:
https://doaj.org/article/4d1be3554a1648f7a95b8e4694bcb0af
Autor:
Hanne Andersen
Publikováno v:
Tidsskrift for Professionsstudier, Vol 17, Iss 33 (2021)
How can research be distinguished from public debate or from nonsense? This question has kept arising in public debates about controversial research topics, for example in debates on Lomborg’s publications on climate and environmental science in th
Externí odkaz:
https://doaj.org/article/b06d35635a4e43bf9af828166bfd3a31
Autor:
Brien K. Haun, Chih-Yun Lai, Caitlin A. Williams, Teri Ann S. Wong, Michael M. Lieberman, Laurent Pessaint, Hanne Andersen, Axel T. Lehrer
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The current COVID-19 pandemic has claimed hundreds of thousands of lives and its causative agent, SARS-CoV-2, has infected millions, globally. The highly contagious nature of this respiratory virus has spurred massive global efforts to develop vaccin
Externí odkaz:
https://doaj.org/article/3750a153e67a4b7f81002677829cc462
Autor:
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne Walker, Edgar Tello‐Ruiz, Sarah T. C. Elliott, Alfredo Perales‐Puchalt, Peng Xiao, Xizhou Zhu, Ruth A. Pumroy, Paul D. Fisher, Katherine Schultheis, Eric Schade, Sergey Menis, Stacy Guzman, Hanne Andersen, Kate E. Broderick, Laurent M. Humeau, Kar Muthumani, Vera Moiseenkova‐Bell, William R. Schief, David B. Weiner, Daniel W. Kulp
Publikováno v:
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Abstract Nanotechnologies are considered to be of growing importance to the vaccine field. Through decoration of immunogens on multivalent nanoparticles, designed nanovaccines can elicit improved humoral immunity. However, significant practical and m
Externí odkaz:
https://doaj.org/article/a5cfd50706de4598866740c702c06b33