Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hanmin Guo"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Polygenic risk scores are used to improve risk prediction for common diseases but typically have reduced accuracy for individuals of non-European ancestry. Here, the authors present an approach that improves polygenic risk score performance in ancest
Externí odkaz:
https://doaj.org/article/a1e062fda2fc420eb11d06392cf93f52
Autor:
Hanmin Guo, Lin Hou, Yu Shi, Sheng Chih Jin, Xue Zeng, Boyang Li, Richard P Lifton, Martina Brueckner, Hongyu Zhao, Qiongshi Lu
Publikováno v:
eLife, Vol 11 (2022)
Exome sequencing on tens of thousands of parent-proband trios has identified numerous deleterious de novo mutations (DNMs) and implicated risk genes for many disorders. Recent studies have suggested shared genes and pathways are enriched for DNMs acr
Externí odkaz:
https://doaj.org/article/b478a942d7ba4b5d8bc9e5c444088253
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Genetic correlation analyses give insight on complex disease, yet are limited by oversimplification. Here, the authors present LOGODetect, a method using summary statistics from genome-wide association studies to identify genomic regions with correla
Externí odkaz:
https://doaj.org/article/5719480cafa349d680319f99b207e396
Autor:
Bo Zhou, Purmann, Carolin, Hanmin Guo, GiWon Shin, Yiling Huang, Pattni, Reenal, Qingxi Meng, Greer, Stephanie U., Roychowdhury, Tanmoy, Wood, Raegan N., Ho, Marcus, zu Dohna, Heinrich, Abyzov, Alexej, Hallmayer, Joachim F., Wong, Wing H., Ji, Hanlee P., Urban, Alexander E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/30/2024, Vol. 121 Issue 31, p1-12, 20p
Publikováno v:
Electronic Journal of Statistics. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98f7d9a77c019fc8a79114c6ae9e91ac
https://doi.org/10.1214/22-ejs1999
https://doi.org/10.1214/22-ejs1999
Autor:
Richard P. Lifton, Boyang Li, Qiongshi Lu, Sheng Chih Jin, Lin Hou, Hongyu Zhao, Martina Brueckner, Hanmin Guo, Yu Shi, Xue Zeng
Exome sequencing on tens of thousands of parent-proband trios has identified numerous deleterious de novo mutations (DNMs) and implicated risk genes for many disorders. Recent studies have suggested shared genes and pathways are enriched for DNMs acr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69d99f5cdf19741999483ec6e89e95a6
https://doi.org/10.1101/2021.06.13.448234
https://doi.org/10.1101/2021.06.13.448234
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Genetic correlation analysis has quickly gained popularity in the past few years and provided insights into the genetic etiology of numerous complex diseases. However, existing approaches oversimplify the shared genetic architecture between different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d08b6a5c415a22a51df83abc20a6d4c
Autor:
Bo Zhou, Joseph G. Arthur, Hanmin Guo, Christopher R. Hughes, Taeyoung Kim, Yiling Huang, Reenal Pattni, HoJoon Lee, Hanlee P. Ji, Giltae Song, Dean Palejev, Xiang Zhu, Wing H. Wong, Alexander E. Urban
Complex structural variants (cxSVs), e.g. inversions with flanking deletions or interspersed inverted duplications, are part of human genetic diversity but their characteristics are not well delineated. Because their structures are difficult to resol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a02e322a1381f80f1a77951b0126bb3
https://doi.org/10.1101/200170
https://doi.org/10.1101/200170
Autor:
Hanmin Guo
Publikováno v:
International Photonics and Optoelectronics Meetings (POEM).
On the basis of the concept of spherical aberration and the phenomena of focal shift, the lateral resolution limitation and the corresponding conditions are demonstrated for the focusing of the dielectric microsphere.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91a222e5eb3b1b62327e8bace24526f
https://doi.org/10.1364/n3.2013.nsu3c.3
https://doi.org/10.1364/n3.2013.nsu3c.3