Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hanmin Gu"'
Publikováno v:
Journal of the Korean Urban Geographical Society. 25:27-40
Publikováno v:
Journal of the Urban Design Institute of Korea Urban Design. 22:5-24
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Polygenic risk scores are used to improve risk prediction for common diseases but typically have reduced accuracy for individuals of non-European ancestry. Here, the authors present an approach that improves polygenic risk score performance in ancest
Externí odkaz:
https://doaj.org/article/a1e062fda2fc420eb11d06392cf93f52
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Genetic correlation analyses give insight on complex disease, yet are limited by oversimplification. Here, the authors present LOGODetect, a method using summary statistics from genome-wide association studies to identify genomic regions with correla
Externí odkaz:
https://doaj.org/article/5719480cafa349d680319f99b207e396
Autor:
Hanmin Guo, Lin Hou, Yu Shi, Sheng Chih Jin, Xue Zeng, Boyang Li, Richard P Lifton, Martina Brueckner, Hongyu Zhao, Qiongshi Lu
Publikováno v:
eLife, Vol 11 (2022)
Exome sequencing on tens of thousands of parent-proband trios has identified numerous deleterious de novo mutations (DNMs) and implicated risk genes for many disorders. Recent studies have suggested shared genes and pathways are enriched for DNMs acr
Externí odkaz:
https://doaj.org/article/b478a942d7ba4b5d8bc9e5c444088253