Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hanmi Xi"'
Autor:
Jing Song, Marc Taraban, Y. Bruce Yu, Lynn Lu, Pallavi Guha Biswas, Wei Xu, Hanmi Xi, Akhilesh Bhambhani, Guangli Hu, Yongchao Su
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTHigh-concentration protein formulation is of paramount importance in patient-centric drug product development, but it also presents challenges due to the potential for enhanced aggregation and increased viscosity. The analysis of critical qua
Externí odkaz:
https://doaj.org/article/8d8f3e96eb104bfea17977931edd4cd5
Autor:
Jing Song, Guangli Hu, Hassen Hamzaoui, Yogita Krishnamachari, Steven C. Persak, Hanmi Xi, Yongchao Su
Publikováno v:
Journal of Pharmaceutical Sciences. 111:3191-3194
Silicone oil is often applied to the inner surface of glass syringes and cartridges to reduce friction between the glass surface and elastomeric plunger stopper. This oil can appear as intrinsic and non-proteinaceous particles in the ejected fluid or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cf009281e70de3bacbd015f8f79685
https://doi.org/10.1016/j.xphs.2022.09.015
https://doi.org/10.1016/j.xphs.2022.09.015
Autor:
Kayla Gentile, Chengbin Huang, Xiaoyang Liu, Laurence Whitty-Léveillé, Hassen Hamzaoui, Eduardo Cristofolli, William Rayfield, Nelson Lee Afanador, Sarita Mittal, Yogita Krishnamachari, Hanmi Xi, Xi Zhao
Publikováno v:
Journal of Pharmaceutical Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0976cf4c5b5e80ff60502b419934cb
https://doi.org/10.1016/j.xphs.2023.05.017
https://doi.org/10.1016/j.xphs.2023.05.017
Autor:
Hanmi Xi, Xiangyu Ma, Mike Marsh, Robert E.A. Williams, Nicolas Piché, Nada Kittikunakorn, Bradley Sorman, Arthur Mongeau, Daniel Skomski, Antong Chen
Publikováno v:
Microscopy and Microanalysis. 26:1606-1609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca245fcb5dbffcdf7b9695653b6aed61
https://doi.org/10.1017/s1431927620018693
https://doi.org/10.1017/s1431927620018693
Autor:
Julie Novak, Gerard R. Klinzing, Gregory A. Johnson, Wei Xu, Jie Ren, Mary Ann Johnson, Hanmi Xi, Eric Kemp
Publikováno v:
Pharmaceutical Research. 37
While including amorphous solid dispersion (ASD) in tablet formulations is increasingly common, tablets containing high ASD loading are associated with slow disintegration, which presents a challenge to control pill burden for less potent compounds.W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abf062786ad2b33278fbaa829ef46d4
https://doi.org/10.1007/s11095-020-2772-7
https://doi.org/10.1007/s11095-020-2772-7
Autor:
Haichen Nie, Patrick J. Marsac, Yongchao Su, Hang Lau, Nico Setiawan, Lynne S. Taylor, Matthew K. Defrese, Jonas Alin, James DiNunzio, Hanmi Xi, Nathan Hesse, Lisa Lupton
Publikováno v:
Polymer. 135:50-60
The utility of amorphization of drug molecules, such as enhanced solubility, dissolution rate and oral bioavailability, has been well exemplified in the literature. Yet, the application of this technique is often hindered by the crystallization liabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2579c68485d1841a71e5ed4bbec19b5a
https://doi.org/10.1016/j.polymer.2017.11.056
https://doi.org/10.1016/j.polymer.2017.11.056
Autor:
Robert Wenslow, Yongchao Su, Freddy A Arce, Nico Setiawan, Alfred C. F. Rumondor, Justin Moser, Pavithra Sundararajan, Sadegh Poozesh, Shawn Zhang, Patrick J. Marsac, Hanmi Xi, Douglas Wei, Joyce Stellabott, Joseph Della Rocca
Publikováno v:
Powder Technology. 320:685-695
A complete description of the particle formation process can only be realized with techniques that enable the measurement of the composition and structural dependence of individual particles. The purpose of this publication is to highlight the utilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f03115fef627590ed9f228029faaa8
https://doi.org/10.1016/j.powtec.2017.07.042
https://doi.org/10.1016/j.powtec.2017.07.042
Autor:
Antong Chen, Bradley Sorman, Mike Marsh, Hanmi Xi, Arthur Mongeau, Robert O. Williams, Daniel Skomski, Nada Kittikunakorn, Nicolas Piché, Xiangyu Ma
Publikováno v:
Journal of pharmaceutical sciences. 109(4)
Tablet defects encountered during the manufacturing of oral formulations can result in quality concerns, timeline delays, and elevated financial costs. Internal tablet cracking is not typically measured in routine inspections but can lead to batch fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a564831c3ffae65d1bd119467c06d7b6
https://pubmed.ncbi.nlm.nih.gov/31982393
https://pubmed.ncbi.nlm.nih.gov/31982393
Publikováno v:
International journal of pharmaceutics. 554
Amorphous Solid Dispersion (ASD) based formulations have been frequently used to improve the bioavailability of poorly water soluble drugs, however, common processes to produce ASDs are not feasible for Absorption, Distribution, Metabolism and Excret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36a636c56b7b0a62a8b1e7d41b54a01
https://pubmed.ncbi.nlm.nih.gov/30236644
https://pubmed.ncbi.nlm.nih.gov/30236644
Publikováno v:
Journal of Chemical Physics; 8/21/2009, Vol. 131 Issue 7, p074506, 9p, 1 Chart, 9 Graphs