A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

Autor: TD Barbara Nguyen-Vu, Grace Q Zhao, Subhaneil Lahiri, Rhea R Kimpo, Hanmi Lee, Surya Ganguli, Carla J Shatz, Jennifer L Raymond

Publikováno v: eLife, Vol 6 (2017)

Across many studies, animals with enhanced synaptic plasticity exhibit either enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can yield opposite learning outcomes? Here, we show that the recent history of experienc

Externí odkaz: https://doaj.org/article/0e2fd4986302466e8fec0a76349b0c39

Current Status and Forecast of Blockchain Application in Security Technology

Autor: Yerin Yu, Hanmi Lee, Jiwon Han, Jungho Kang

Publikováno v: Lecture Notes in Electrical Engineering ISBN: 9789811593086

The security industry has recently paid attention to distributed ledger technology as the fundamental concept of blockchain, and it is utilizing the technology’s transparency and integrity features in a variety of security applications. This paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3161553cf5dbbf494efb71e71f056ed9
https://doi.org/10.1007/978-981-15-9309-3_14

KCC2 expression in immature rat cortical neurons is sufficient to switch the polarity of GABA responses

Autor: Carol Xiu-Qing Chen, Yong-Jian Liu, Hanmi Lee, Karl Kandler, Elias Aizenman

Publikováno v: European Journal of Neuroscience. 21:2593-2599

During brain development, GABA and glycine switch from being depolarizing to being hyperpolarizing neurotransmitters. This conversion results from a gradual decrease in the chloride electrochemical equilibrium potential (ECl) of developing neurons, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3a2d7e9282938fda3f5d05cb3f7e90
https://doi.org/10.1111/j.1460-9568.2005.04084.x

Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia

Autor: David N. Bochner, Richard W. Sapp, Jaimie D. Adelson, Siyu Zhang, Hanmi Lee, Maja Djurisic, Josh Syken, Yang Dan, Carla J. Shatz

Publikováno v: Bochner, DN; Sapp, RW; Adelson, JD; Zhang, S; Lee, H; Djurisic, M; et al.(2014). Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia. Science Translational Medicine, 6(258), 258ra140. doi: 10.1126/scitranslmed.3010157. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/9m6648rn

During critical periods of development, the brain easily changes in response to environmental stimuli, but this neural plasticity declines by adulthood. By acutely disrupting paired immunoglobulin-like receptor B (PirB) function at specific ages, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f2a77a0cbcb73dc53a8c0c9a2277f1
http://www.escholarship.org/uc/item/9m6648rn

A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity.

Autor: Nguyen-Vu, T. D. Barbara, Zhao, Grace Q., Lahiri, Subhaneil, Kimpo, Rhea, Hanmi Lee, Surya Ganguli, Shatz, Carla J., Raymond, Jennifer L.

Publikováno v: eLife; Feb2017, p1-72, 91p