Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hanlin Tao"'
Autor:
Bin Cao, Shengkan Jin, Victor M. Tan, Amer Alasadi, Jingjing Guo, Juan Collantes, Hanlin Tao, Xiaoyang Su, David Augeri
Publikováno v:
Oncogene. 40:2285-2295
Pancreatic ductal adenocarcinoma (PDA) is aggressive cancer characterized by rapid progression, metastatic recurrence, and highly resistant to treatment. PDA cells exhibit aerobic glycolysis, or the Warburg effect, which reduces the flux of pyruvate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72699e6ef5d88cdcffb9ae0144a793c7
https://doi.org/10.1038/s41388-021-01688-7
https://doi.org/10.1038/s41388-021-01688-7
Autor:
Victor M. Tan, Shengkan Jin, Katarzyna M. Tyc, Melany Ruiz-Urigüen, Jennifer A. Harbottle, Ceri M. Wiggins, Juan Collantes, Jinchuan Xing, John J. Lambourne, Hanlin Tao, Chi Su, Amer Alasadi, Jingjing Guo, Huiting Xu, Tommaso Selmi, Jesse Stombaugh
Publikováno v:
CRISPR J
Conventional CRISPR approaches for precision genome editing rely on the introduction of DNA double-strand breaks (DSB) and activation of homology-directed repair (HDR), which is inherently genotoxic and inefficient in somatic cells. The development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b22b5ff1417128252b11da8202ac8a
https://doi.org/10.1089/crispr.2020.0035
https://doi.org/10.1089/crispr.2020.0035
Autor:
Noor Fadhil, Amer Alasadi, Jingjing Guo, Gaetano T. Montelione, Juan Collantes, Shengkan Jin, Michael Chen, Hanlin Tao, G. V. T. Swapna
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-14 (2018)
Cell Death and Disease, Vol 9, Iss 2, Pp 1-14 (2018)
Metabolism of cancer cells is characterized by aerobic glycolysis, or the Warburg effect. Aerobic glycolysis reduces pyruvate flux into mitochondria, preventing a complete oxidation of glucose and shunting glucose to anabolic pathways essential for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018c135b1bc6993c642a97a530736dd5
https://pubmed.ncbi.nlm.nih.gov/29440715
https://pubmed.ncbi.nlm.nih.gov/29440715
Autor:
Haiyan Zhang, Claude E Monken, Shengkan Jin, Joseph G. Moloughney, Hanlin Tao, Edmund C. Lattime, Janice D. Thomas
Publikováno v:
Autophagy
The interactions between viruses and cellular autophagy have been widely reported. On the one hand, autophagy is an important innate immune response against viral infection. On the other hand, some viruses exploit the autophagy pathway for their surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40b34c09039c39af8a95ec9a29b2eab
Publikováno v:
Nature medicine. 20(11)
Type 2 diabetes (T2D) has reached an epidemic level globally. Most current treatments ameliorate the hyperglycemic symptom of the disease but are not effective in correcting its underlying cause. One important causal factor of T2D is ectopic accumula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2614bdde01770af48e1940894c14f47
https://pubmed.ncbi.nlm.nih.gov/25394871
https://pubmed.ncbi.nlm.nih.gov/25394871
Publikováno v:
Adipose Tissue and Adipokines in Health and Disease ISBN: 9781627037693
Autophagy is a mechanism for intracellular degradation of cytoplasmic components including macromolecules and organelles. It has been shown to be involved in a large number of physiological and pathological processes. Studies have recently uncovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62411ddb6e8080b482edd92af0d8f7b2
https://doi.org/10.1007/978-1-62703-770-9_9
https://doi.org/10.1007/978-1-62703-770-9_9
Publikováno v:
Autophagy and Cancer ISBN: 9781461465607
Autophagy is an evolutionarily conserved cytoplasmic degradation pathway. A fundamental function of autophagy at the cellular level is to recycle cytoplasmic components, including macromolecules and organelles. Autophagy is essential for cell surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89b06c81beac47bac243ee39bea118eb
https://doi.org/10.1007/978-1-4614-6561-4_5
https://doi.org/10.1007/978-1-4614-6561-4_5
Publikováno v:
Cancer Research. 76:45-45
One fundamental change in cancer cells in oncogenesis is the alteration of glucose metabolism. With few exceptions, cancer cells exhibit aerobic glycolysis. A majority of pyruvate derived from glycolysis is converted to lactate instead of entering mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e3e9e924fa09b966e6adf9094f3abde
https://doi.org/10.1158/1538-7445.am2016-45
https://doi.org/10.1158/1538-7445.am2016-45
Publikováno v:
Journal of Agricultural & Food Chemistry; 3/16/2016, Vol. 64 Issue 10, p2053-2061, 9p
Autor:
Moloughney, Joseph G., Monken, Claude E., Hanlin Tao, Haiyan Zhang, Thomas, Janice D., Lattime, Edmund C., Shengkan Jin
Publikováno v:
Autophagy; Dec2011, Vol. 7 Issue 12, p1434-1447, 15p