Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hankyoung Pyo"'
Publikováno v:
Neuroscience Letters. 346:141-144
Microglia, the primary inflammatory cells in the brain, are activated upon brain injury. Activated microglia produce nitric oxide (NO), a major toxin to neuronal cells. It has been reported that astrocytes inhibit microglial activation. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3fcfc77a333e1dfb556984c5bd09a2
https://doi.org/10.1016/s0304-3940(03)00505-6
https://doi.org/10.1016/s0304-3940(03)00505-6
Autor:
Soung Soo Kim, Ilo Jou, Jooyoung Ryu, Hankyoung Pyo, Tae Hyong Kim, Byung-Kwan Jin, Eun-Hye Joe, Kyoung-Jin Min, Seung-Up Kim, Tai Youn Rhim
Publikováno v:
The Journal of Immunology. 168:5805-5810
Microglia, the major immune effector cells in the CNS, become activated when the brain suffers injury. In this study, we observed that prothrombin, a zymogen of thrombin, induced NO release and mRNA expression of inducible NO synthase, IL-1β, and TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d26b0e8b33c08c8bfafc1df3fe5e1b9
https://doi.org/10.4049/jimmunol.168.11.5805
https://doi.org/10.4049/jimmunol.168.11.5805
Publikováno v:
Journal of Biological Chemistry. 275:29955-29959
Microglia, brain resident macrophages, become activated in brains injured due to trauma, ischemia, or neurodegenerative diseases. In this study, we found that thrombin treatment of microglia induced NO release/inducible nitric-oxide synthase expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1410d5795e30dc68a75a755576425cb
https://doi.org/10.1074/jbc.m001220200
https://doi.org/10.1074/jbc.m001220200
Publikováno v:
Journal of Biological Chemistry. 274:34584-34589
Microglia, brain resident macrophages, are activated in brain injuries and several neurodegenerative diseases. However, microglial activators that are produced in the brain are not yet defined. In this study, we showed that gangliosides, sialic acid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790bc59ced7c29f413e890aeaafc5fdd
https://doi.org/10.1074/jbc.274.49.34584
https://doi.org/10.1074/jbc.274.49.34584
Publikováno v:
Glia. 24:408-414
We examined the expression of outward rectifier K+ channels in activated microglia in vivo. For this purpose, lipopolysaccharide (LPS, 2 μg) was injected into the cortex near the hippocampal region of rat brains, and K+ channel expression was examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::729544290d4a7b6b93a781c2957f2380
https://doi.org/10.1002/(sici)1098-1136(199812)24:4<408::aid-glia6>3.0.co
https://doi.org/10.1002/(sici)1098-1136(199812)24:4<408::aid-glia6>3.0.co
Publikováno v:
NeuroReport. 9:871-874
To test whether mitogen-activated protein kinases (MAPKs) are involved in microglial activation, pure microglia prepared from 1- to 3-day-old rat brains were activated with either 100 ng/ml lipopolysaccharide (LPS) or 5 nM synthetic beta-amyloid (Abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604da3b51798c33602e3a107f14ca059
https://doi.org/10.1097/00001756-199803300-00020
https://doi.org/10.1097/00001756-199803300-00020