Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Hank Simms"'
Publikováno v:
In BBA - Molecular Basis of Disease 2004 1689(3):212-218
Autor:
Rongqian Wu, Michael Miksa, Ping Wang, Padmalaya Das, Thanjavur S. Ravikumar, Weifeng Dong, H. Hank Simms, Xiaoxuan Cui
Publikováno v:
The Journal of Immunology. 179:6263-6272
Sepsis is a critical inflammatory condition from which numerous patients die due to multiple organ failure and septic shock. The vasoactive hormone adrenomedullin (AM) and its binding protein (AMBP-1) are beneficial in sepsis by abrogating the progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adf14ba2710cdcb00313cf2765d4cf5
https://doi.org/10.4049/jimmunol.179.9.6263
https://doi.org/10.4049/jimmunol.179.9.6263
Autor:
Mian Zhou, Ping Wang, Thanjavur S. Ravikumar, H. Hank Simms, Corrado P. Marini, Rongqian Wu, Weifeng Dong
Publikováno v:
Critical Care Medicine. 35:912-918
Management of trauma victims with uncontrolled hemorrhage remains a major problem in combat casualty care at the far-forward battlefield setting. The neuroendocrine response to hemorrhage is to maintain perfusion to the heart and brain, often at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77db47b2c519df88c45830edf744a7b
https://doi.org/10.1097/01.ccm.0000257327.61829.34
https://doi.org/10.1097/01.ccm.0000257327.61829.34
Publikováno v:
Surgery. 141:245-253
Background Recent studies have shown that adrenomedullin (AM) and AM-binding protein-1 (AMBP-1) possess anti-inflammatory properties in sepsis. We hypothesized that administration of AM/AMBP-1 after gut ischemia-reperfusion (I/R) downregulates inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638342ba99b5fe853fccc26d843273cf
https://doi.org/10.1016/j.surg.2006.05.017
https://doi.org/10.1016/j.surg.2006.05.017
Autor:
Ivana Vancurova, Maowen Hu, Ping Wang, H. Hank Simms, Xinchun Lin, Edmund J. Miller, Qiaoting Du
Publikováno v:
Critical Care Medicine. 33:2571-2578
Despite advances in the management of sepsis and acute respiratory distress syndrome, the mortality rate remains high. Delayed apoptosis of neutrophils is associated with multiple organ failure under those conditions. Thus, development of nontoxic ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ffbb3fd27520e10b42d7a16762add3
https://doi.org/10.1097/01.ccm.0000186760.20502.c7
https://doi.org/10.1097/01.ccm.0000186760.20502.c7
Publikováno v:
Cardiovascular Research. 68:318-326
Objectives: Severe sepsis is associated with increased total peripheral resistance (TPR) and decreased organ blood flow, in which endothelin-1 ( ET-1 ) plays an important role. Plasma levels of ghrelin, a newly-identified endogenous ligand for growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d19567a2da293e1a0ac4c41c17c221
https://doi.org/10.1016/j.cardiores.2005.06.011
https://doi.org/10.1016/j.cardiores.2005.06.011
Publikováno v:
Annals of Surgery. 242:115-123
Trauma is the leading cause of death in the population between ages 1 to 44 and one of the leading causes of death in those over age 65 in the United States. It results in approximately 150,000 deaths per year.1,2 Most trauma deaths result either fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538bcc4592f94263aa1fc73c525b72c7
https://doi.org/10.1097/01.sla.0000167849.10599.30
https://doi.org/10.1097/01.sla.0000167849.10599.30
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1740(3):446-452
Previous studies have shown that the gut is a major source of norepinephrine (NE) released in early sepsis and that gut-derived NE plays an important role in up-regulating TNF-alpha expression in Kupffer cells (KC) via an alpha(2)-adrenoceptor (alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd8a3a5df0ffc4a08be78af7cab0454
Autor:
Haichao Wang, Rongqian Wu, H. Hank Simms, Weifeng Dong, Mian Zhou, Ping Wang, Luis Ulloa, F. Huan Yang, Kevin J. Tracey, Xiaoxuan Cui
Publikováno v:
Critical Care Medicine. 33:391-398
Objective The neuroendocrine response to hemorrhage is to maintain perfusion to the heart and brain, often at the expense of other organ systems. Systemic inflammation and tissue injury are important components of pathophysiologic consequences of hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24ef0bbed72dd89f69f81c34caf2692
https://doi.org/10.1097/01.ccm.0000153416.41398.a9
https://doi.org/10.1097/01.ccm.0000153416.41398.a9
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 287:H1296-H1302
Ghrelin, a newly identified endogenous ligand for growth hormone secretagogue receptor 1a (GHSR-1a, i.e., ghrelin receptor), was recently demonstrated to be a potent vasoactive peptide. Although sepsis is characterized by an early, hyperdynamic phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cd2665c65689fbf9bcc51dc3a50995
https://doi.org/10.1152/ajpheart.00852.2003
https://doi.org/10.1152/ajpheart.00852.2003