Zobrazeno 1 - 10 of 397 pro vyhledávání: '"Hank F, Kung"'
1
Akademický článek
First-in-human study of D6-[18F]FP-(+)-DTBZ, a novel VMAT2 tracer: whole-body biodistribution and brain PET comparison with [18F]FP-(+)-DTBZ (AV-133)
Autor: Ruiyue Zhao, Jinhua Chen, Ting Ye, Jianmin Chu, Jingwen Li, Yan Zhang, Siran Xu, Shaoyu Liu, Ling Chen, Karl Ploessl, David Alexoff, Hank F. Kung, Lin Zhu, Xinlu Wang
Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Background In the central nervous system, type 2 vesicular monoamine transporters (VMAT2) are responsible for the reuptake of monoamines from synaptic junction back to pre-synaptic terminal vesicles. These transporters are functionally cruci
Externí odkaz: https://doaj.org/article/c1d4787de487454aa9d814fece62d92d
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2
Akademický článek
68Ga-P15-041, A Novel Bone Imaging Agent for Diagnosis of Bone Metastases
Autor: Rui Guo, Xiangxi Meng, Fei Wang, Jiangyuan Yu, Qing Xie, Wei Zhao, Lin Zhu, Hank F. Kung, Zhi Yang, Nan Li
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
Objectives68Ga-P15-041 (68Ga-HBED-CC-BP) is a novel bone-seeking PET radiotracer, which can be readily prepared by using a simple kit formulation and an in-house 68Ga/68Ge generator. The aim of this study is to assess the potential human application
Externí odkaz: https://doaj.org/article/d5d9d4b18ae24db89d5f0e7688d24e3f
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3
Akademický článek
Evaluating [68Ga]Ga-p14-032 as a Novel PET Tracer for Diagnosis Cerebral Amyloid Angiopathy
Autor: Qihui Zhang, Xiaobin Zhao, Peng Lei, Hank F. Kung, Zhi Yang, Lin Zhu, Shujing Wang, Hua Zhu, Xiangxi Meng, Yunyun Duan, Li Sun, Jianwei Pan, Ruixue Ma, Haiyan Hong, Xingquan Zhao, Andrew Demchuk, Eric E. Smith, Yongjun Wang
Publikováno v: Frontiers in Neurology, Vol 12 (2021)
Objective: We aimed to investigate the distribution of [68Ga]Ga-p14-032, a novel PET ligand that binds to vascular amyloid, in patients diagnosed clinically with probable cerebral amyloid angiopathy (CAA) compared with patients with Alzheimer's disea
Externí odkaz: https://doaj.org/article/f811d0ed432c41d5b57ac5567e0d56e5
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8
New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177)
Autor: Zhihao Zha, Seok Rye Choi, Linlin Li, Ruiyue Zhao, Karl Ploessl, Xinyue Yao, David Alexoff, Lin Zhu, Hank F. Kung
Publikováno v: Journal of Medicinal Chemistry. 65:13001-13012
Prostate-specific membrane antigen (PSMA) is a promising target for the diagnosis and radionuclide therapy of prostate cancer. This study reports conversion of a previously reported
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd42809d9abe59bfb1fbf0e345f7ffe
https://doi.org/10.1021/acs.jmedchem.2c00852
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9
Akademický článek
Synthesis of novel technetium-99m tricarbonyl-HBED-CC complexes and structural prediction in solution by density functional theory calculation
Autor: Shengyu Shi, Lifeng Yao, Linlin Li, Zehui Wu, Zhihao Zha, Hank F. Kung, Lin Zhu, De-Cai Fang
Publikováno v: Royal Society Open Science, Vol 6, Iss 11 (2019)
HBED-CC (N,N'-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylene diamine-N,N'-diacetic acid, L1) is a common bifunctional chelating agent in preparation of 68Ga-radiopharmaceuticals. Due to its high stability constant for the Ga3+ complex (logKGaL = 38.5)
Externí odkaz: https://doaj.org/article/172e041be94e4a4599a5991cc41a03ee
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