Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hanigan TW"'
Autor:
Amy R. Howell, Kevin Shannon, Anthony D. Long, Predovic M, Bihua Huang, Remsberg, Inguva A, Micah J. Niphakis, Nhi Ngo, Radu M. Suciu, Stewart K. Richardson, Kenneth M. Lum, Hanigan Tw, Firestone Aj, Cassandra L. Henry, Benjamin F. Cravatt, Zambetti Na
A subset of Ras proteins, including N-Ras, depend on a palmitoylation/depalmitoylation cycle to regulate their subcellular trafficking and oncogenicity. General lipase inhibitors such as Palmostatin M block N-Ras depalmitoylation, but lack specificit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee779cfd11259dabc59a9be1a2d0354a
https://doi.org/10.1101/2020.05.21.108316
https://doi.org/10.1101/2020.05.21.108316
Autor:
Lazear MR; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Remsberg JR; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA. Electronic address: remsberg@scripps.edu., Jaeger MG; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Rothamel K; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Her HL; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., DeMeester KE; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Njomen E; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Hogg SJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA., Rahman J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA., Whitby LR; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA., Won SJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Schafroth MA; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Ogasawara D; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Yokoyama M; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Lindsey GL; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Li H; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Germain J; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Barbas S; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Vaughan J; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Hanigan TW; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Vartabedian VF; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA., Reinhardt CJ; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Dix MM; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA., Koo SJ; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium., Heo I; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium., Teijaro JR; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA., Simon GM; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA., Ghosh B; Discovery Chemistry, Janssen Research & Development, Spring House, PA 19477, USA., Abdel-Wahab O; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA., Ahn K; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Spring House, PA 19477, USA., Saghatelian A; Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA, USA., Melillo B; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02142, USA., Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Yeo GW; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Cravatt BF; Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA. Electronic address: cravatt@scripps.edu.
Publikováno v:
Molecular cell [Mol Cell] 2023 May 18; Vol. 83 (10), pp. 1725-1742.e12. Date of Electronic Publication: 2023 Apr 20.
Autor:
Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Zambetti NA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Hanigan TW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Firestone AJ; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Inguva A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Long A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Ngo N; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Lum KM; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Henry CL; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Richardson SK; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Predovic M; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Huang B; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Dix MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Howell AR; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Niphakis MJ; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA. MIIP@lundbeck.com., Shannon K; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. cravatt@scripps.edu.
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2021 Aug; Vol. 17 (8), pp. 856-864. Date of Electronic Publication: 2021 Apr 29.
Autor:
Taha TY, Aboukhatwa SM, Knopp RC, Ikegaki N, Abdelkarim H, Neerasa J, Lu Y, Neelarapu R, Hanigan TW, Thatcher GRJ, Petukhov PA
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Aug 02; Vol. 10 (9), pp. 1358. Date of Electronic Publication: 2019 Aug 02 (Print Publication: 2019).
Autor:
Aboukhatwa SM; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt., Hanigan TW; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA., Taha TY; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA., Neerasa J; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA., Ranjan R; Section of Hematology/Oncology, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA., El-Bastawissy EE; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt., Elkersh MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University, Alexandria, 21311, Egypt., El-Moselhy TF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, 31527, Egypt., Frasor J; Department of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA., Mahmud N; Section of Hematology/Oncology, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA., McLachlan A; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA., Petukhov PA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA.
Publikováno v:
ChemMedChem [ChemMedChem] 2019 Jun 05; Vol. 14 (11), pp. 1096-1107. Date of Electronic Publication: 2019 Apr 10.
Autor:
Hanigan TW; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, 833 South Wood Street, Chicago, IL 60612, USA., Danes JM; Department of Physiology and Biophysics, College of Medicine, University of Illinois, 835 S. Wolcott Street, Chicago, IL 60612, USA., Taha TY; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, 833 South Wood Street, Chicago, IL 60612, USA., Frasor J; Department of Physiology and Biophysics, College of Medicine, University of Illinois, 835 S. Wolcott Street, Chicago, IL 60612, USA., Petukhov PA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, 833 South Wood Street, Chicago, IL 60612, USA.
Publikováno v:
Journal of biological methods [J Biol Methods] 2018; Vol. 5 (1).
Autor:
Hanigan TW; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA., Aboukhatwa SM; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt 31527., Taha TY; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA., Frasor J; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL 60612, USA., Petukhov PA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA. Electronic address: pap4@uic.edu.
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2017 Nov 16; Vol. 24 (11), pp. 1356-1367.e8. Date of Electronic Publication: 2017 Sep 21.
Autor:
Hanigan TW; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America., Taha TY; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America., Aboukhatwa SM; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt., Frasor J; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois, United States of America., Petukhov PA; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America.
Publikováno v:
PloS one [PLoS One] 2017 Oct 18; Vol. 12 (10), pp. e0186620. Date of Electronic Publication: 2017 Oct 18 (Print Publication: 2017).
Autor:
Taha TY; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Aboukhatwa SM; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt., Knopp RC; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Ikegaki N; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Abdelkarim H; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Neerasa J; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Lu Y; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Neelarapu R; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Hanigan TW; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Thatcher GRJ; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Petukhov PA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2017 Aug 01; Vol. 8 (8), pp. 824-829. Date of Electronic Publication: 2017 Aug 01 (Print Publication: 2017).