Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hanifa J Abu Toamih-Atamni"'
Autor:
Alexandra Dorman, Ilona Binenbaum, Hanifa J. Abu-Toamih Atamni, Aristotelis Chatziioannou, Ian Tomlinson, Richard Mott, Fuad A. Iraqi
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Familial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis coli (Apc) gene. Mice carrying a nonsense mutation in the Apc
Externí odkaz:
https://doaj.org/article/b81d6b2b52404974967629e9b9d9a2b9
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 1, Pp 27-39 (2021)
Abstract Background Multimorbidity of intestinal cancer (IC), type 2 diabetes (T2D) and obesity is a complex set of diseases, affected by environmental and genetic risk factors. High‐fat diet (HFD) and oral bacterial infection play important roles
Externí odkaz:
https://doaj.org/article/2dfec970666f49f28ba3a1e222b1bb10
Publikováno v:
Animal Models and Experimental Medicine, Vol 3, Iss 2, Pp 152-159 (2020)
Abstract Background Host genetic background and sex, play central roles in defining the pathogenesis of type 2 diabetes (T2D), obesity and infectious diseases. Our previous studies demonstrated the utilization of genetically highly diverse inbred mou
Externí odkaz:
https://doaj.org/article/f22a2257dca9457f837d7591d6b9fb1e
Publikováno v:
Animal Models and Experimental Medicine, Vol 2, Iss 3, Pp 137-149 (2019)
Abstract The Collaborative Cross (CC) mouse model is a next‐generation mouse genetic reference population (GRP) designated for a high‐resolution quantitative trait loci (QTL) mapping of complex traits during health and disease. The CC lines were
Externí odkaz:
https://doaj.org/article/f133404506954b04b6c85baaf15fdd6c
Autor:
Remco T. Molenhuis, Hilgo Bruining, Myrna J. V. Brandt, Petra E. van Soldt, Hanifa J. Abu-Toamih Atamni, J. Peter H. Burbach, Fuad A. Iraqi, Richard F. Mott, Martien J. H. Kas
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-11 (2018)
Abstract Background Animal models for neurodevelopmental disorders (NDD) generally rely on a single genetic mutation on a fixed genetic background. Recent human genetic studies however indicate that a clinical diagnosis with Autism Spectrum Disorder
Externí odkaz:
https://doaj.org/article/49bbf165784c41c5a77fe037b30fc85c
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 1, Pp 27-39 (2021)
Animal Models and Experimental Medicine
Animal Models and Experimental Medicine
Background Multimorbidity of intestinal cancer (IC), type 2 diabetes (T2D) and obesity is a complex set of diseases, affected by environmental and genetic risk factors. High‐fat diet (HFD) and oral bacterial infection play important roles in the et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45e18f3acf586b890c1578dec00ccfb
https://doaj.org/article/2dfec970666f49f28ba3a1e222b1bb10
https://doaj.org/article/2dfec970666f49f28ba3a1e222b1bb10
Autor:
Aharon Nachshon, Hanifa J. Abu-Toamih Atamni, Yael Steuerman, Roa’a Sheikh-Hamed, Alexandra Dorman, Richard Mott, Juliane C. Dohm, Marc Sultan, Hans Lehrach, Ron Shamir, Sascha Sauer, Heinz Himmelbauer, Fuad A. Iraqi, Irit Gat-Viks
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
A central challenge in pharmaceutical research is to investigate genetic variation in response to drugs. The Collaborative Cross (CC) mouse reference population is a promising model for pharmacogenomic studies because of its large amount of genetic v
Externí odkaz:
https://doaj.org/article/467cb5cd4a104b378b025bb17393c29c
Autor:
Alexandra, Dorman, Ilona, Binenbaum, Hanifa J, Abu-Toamih Atamni, Aristotelis, Chatziioannou, Ian, Tomlinson, Richard, Mott, Fuad A, Iraqi
Publikováno v:
BMC Genomics
Background Familial adenomatous polyposis is an inherited genetic disease, characterized by colorectal polyps. It is caused by inactivating mutations in the Adenomatous polyposis coli (Apc) gene. Mice carrying a nonsense mutation in the Apc gene at R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06295ef4b45568bdc33ab331853a9f60
https://pubmed.ncbi.nlm.nih.gov/34294033
https://pubmed.ncbi.nlm.nih.gov/34294033
Autor:
Lisa J. Strug, Alessandra Bragonzi, Barbara Sipione, Hanifa J. Abu-Toamih Atamni, Alexandra Dorman, Fuad A. Iraqi, Richard Mott, Nicola Ivan Lorè, Gengming He
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e00097-20 (2020)
mBio
mBio, Vol 11, Iss 2, p e00097-20 (2020)
Respiratory infection caused by P. aeruginosa is one of the most critical health burdens worldwide. People affected by P. aeruginosa infection include patients with a weakened immune system, such as those with cystic fibrosis (CF) genetic disease or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3e7b7bf04456a55f309a8e97abf9fd
https://doi.org/10.1128/mbio.00097-20
https://doi.org/10.1128/mbio.00097-20
Publikováno v:
Animal Models and Experimental Medicine
Animal Models and Experimental Medicine, Vol 3, Iss 2, Pp 152-159 (2020)
Animal Models and Experimental Medicine, Vol 3, Iss 2, Pp 152-159 (2020)
Background Host genetic background and sex, play central roles in defining the pathogenesis of type 2 diabetes (T2D), obesity and infectious diseases. Our previous studies demonstrated the utilization of genetically highly diverse inbred mouse lines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f17fe981579a4d0d4520643bb6aba7
https://pubmed.ncbi.nlm.nih.gov/32613174
https://pubmed.ncbi.nlm.nih.gov/32613174