Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hani J. Shayya"'
Autor:
Darpan Saraswat, Hani J. Shayya, Jessie J. Polanco, Ajai Tripathi, R. Ross Welliver, Suyog U. Pol, Richard A. Seidman, Jacqueline E. Broome, Melanie A. O’Bara, Toin H. van Kuppervelt, Joanna J. Phillips, Ranjan Dutta, Fraser J. Sim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Demyelination results in impairments in oligodendrocyte progenitor cell recruitment. Here the authors identify sulfatase 1/2 as a potential modulator of myelination by modulating the microenvironment around oligodendrocyte progenitor cells.
Externí odkaz:
https://doaj.org/article/8405f74419104281af9993328f364b19
Autor:
Suyog U. Pol, Jessie J. Polanco, Richard A. Seidman, Melanie A. O'Bara, Hani J. Shayya, Karen C. Dietz, Fraser J. Sim
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 710-723 (2017)
Summary: Impaired human oligodendrocyte progenitor cell (hOPC) differentiation likely contributes to failed remyelination in multiple sclerosis. The characterization of molecular pathways that regulate hOPC differentiation will provide means to induc
Externí odkaz:
https://doaj.org/article/9b894d1cfb8d4db6bcd2ef3678c96df5
Autor:
Jing Wang, Darpan Saraswat, Anjali K. Sinha, Jessie Polanco, Karen Dietz, Melanie A. O’Bara, Suyog U. Pol, Hani J. Shayya, Fraser J. Sim
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3435-3450.e6 (2018)
Summary: Human oligodendrocyte progenitor cells (hOPCs) persist into adulthood as an abundant precursor population capable of division and differentiation. The transcriptional mechanisms that regulate hOPC homeostasis remain poorly defined. Herein, w
Externí odkaz:
https://doaj.org/article/d1aa823735b24a81918352846063fe6d
Autor:
Hani J. Shayya, Jerome K. Kahiapo, Rachel Duffié, Katherine S. Lehmann, Lisa Bashkirova, Kevin Monahan, Ryan P. Dalton, Joanna Gao, Song Jiao, Ira Schieren, Leonardo Belluscio, Stavros Lomvardas
Publikováno v:
Cell. 185(21)
Olfactory sensory neurons (OSNs) convert the stochastic choice of one of1,000 olfactory receptor (OR) genes into precise and stereotyped axon targeting of OR-specific glomeruli in the olfactory bulb. Here, we show that the PERK arm of the unfolded pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5053b9e6dc4777acd152ec1d69b516
https://pubmed.ncbi.nlm.nih.gov/36167070
https://pubmed.ncbi.nlm.nih.gov/36167070
Autor:
Jacqueline E. Broome, Ajai Tripathi, Fraser J. Sim, Darpan Saraswat, Suyog Pol, Ranjan Dutta, R. Ross Welliver, Melanie A. O'Bara, Hani J. Shayya, Jessie J. Polanco, Richard A. Seidman, Joanna J. Phillips, Toin H. van Kuppervelt
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Chronic demyelination in the human CNS is characterized by an inhibitory microenvironment that impairs recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) leading to failed remyelination and axonal atrophy. By network-based tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd869a845f4787f2e1d1c13a69c255d
https://doi.org/10.1038/s41467-021-22263-4
https://doi.org/10.1038/s41467-021-22263-4
Autor:
Jonathan B. Overdevest, Stuart Firestein, John F. Fullard, Qizhi Gong, Stavros Lomvardas, Panos Roussos, Marianna Zazhytska, Albana Kodra, Arina D. Omer, Benjamin R. tenOever, Hani J Shayya, Daisy A. Hoagland, Peter Canoll, James E. Goldman
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Olfaction relies on a coordinated partnership between odorant flow and neuronal communication. Disruption in our ability to detect odors, or anosmia, has emerged as a hallmark symptom of infection with SARS-CoV-2, yet the mechanism behind this abrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c3f7264f19a9075f8196c432a6581b
http://europepmc.org/articles/PMC7885920
http://europepmc.org/articles/PMC7885920
Autor:
Stavros Lomvardas, John F. Fullard, Albana Kodra, Stuart Firestein, Jonathan B. Overdevest, Rasmus Moeller, Marianna Zazhytska, Peter Canoll, Qizhi Gong, James E. Goldman, Daisy A. Hoagland, Arina D. Omer, Benjamin R. tenOever, Hani J Shayya, Panos Rousos, Skyler Uhl
Publikováno v:
SSRN Electronic Journal.
SARS-CoV-2 infects less than 1% of cells in the human body, yet it can cause severe damage in a variety of organs. Thus, deciphering the non-cell autonomous effects of SARS-CoV-2 infection is imperative for understanding the cellular and molecular di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6750a8db022fa0e214eedbbdc15190d1
https://doi.org/10.2139/ssrn.3900127
https://doi.org/10.2139/ssrn.3900127
Autor:
Monica P. Goldklang, Merly C. Vogt, David T. Ng, Stylianos Kosmidis, Felix Fiederling, Hani J Shayya, Urvashi V Thopte, Ana Pinharanda, Armen G. Enikolopov, Ashok Litwin-Kumar, Ines Rodrigues-Vaz, Tanya Tabachnik, Enrico Cannavò, Jeanine D'Armiento, Kyle Stearns, Peter Andolfatto, Barbara Noro, Andres Bendesky, Darcy S. Peterka
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257464 (2021)
PLoS ONE
PLoS ONE
Despite the development of effective vaccines against SARS-CoV-2, epidemiological control of the virus is still challenging due to slow vaccine rollouts, incomplete vaccine protection to current and emerging variants, and unwillingness to get vaccina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439f76a68b37443ed39c6b1e3cc5dcb1
https://doaj.org/article/40755ad4580445b78521b0b9e5301357
https://doaj.org/article/40755ad4580445b78521b0b9e5301357
Autor:
Darpan Saraswat, Hani J. Shayya, Jessie J. Polanco, Ajai Tripathi, R. Ross Welliver, Suyog U. Pol, Richard A. Seidman, Jacqueline E. Broome, Melanie A. O’Bara, Toin H. van Kuppervelt, Joanna J. Phillips, Ranjan Dutta, Fraser J. Sim
Chronic demyelination in the human CNS is characterized by an inhibitory microenvironment that impairs recruitment and differentiation of oligodendrocyte progenitor cells (OPCs) leading to failed remyelination and axonal atrophy. By network-based tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce361fd858496b65b53a4a6dfad2c9de
Autor:
Karen C. Dietz, Jessie J. Polanco, Richard A. Seidman, Suyog Pol, Fraser J. Sim, Melanie A. O'Bara, Hani J. Shayya
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 710-723 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Impaired human oligodendrocyte progenitor cell (hOPC) differentiation likely contributes to failed remyelination in multiple sclerosis. The characterization of molecular pathways that regulate hOPC differentiation will provide means to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03abbb9349bd294ea1928a90199edc0
http://www.sciencedirect.com/science/article/pii/S221367111730317X
http://www.sciencedirect.com/science/article/pii/S221367111730317X