Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Hani A. Awad"'
Autor:
Ming Yan, Hani A. Awad
Publikováno v:
Frontiers in Materials, Vol 10 (2023)
Introduction: Low-temperature extrusion three-dimensional printing (LTE-3DP) using viscous ceramic-polymer inks has shown promise for bone tissue engineering. This process involves formulating a flowable ink by combining ceramic powders and other com
Externí odkaz:
https://doaj.org/article/a6755d43cad2435a9bc37fe5ea65cce8
Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse
Autor:
Jacob G. Kallenbach, Margaret A. T. Freeberg, David Abplanalp, Rahul G. Alenchery, Raquel E. Ajalik, Samantha Muscat, Jacquelyn A. Myers, John M. Ashton, Alayna Loiselle, Mark R. Buckley, Andre J. van Wijnen, Hani A. Awad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract To better understand the molecular mechanisms of tendon healing, we investigated the Murphy Roth’s Large (MRL) mouse, which is considered a model of mammalian tissue regeneration. We show that compared to C57Bl/6J (C57) mice, injured MRL t
Externí odkaz:
https://doaj.org/article/7e3b5540b6894b6b9b78695061d18e3e
Autor:
Molly C. McCloskey, Victor Z. Zhang, S. Danial Ahmad, Samuel Walker, Samantha S. Romanick, Hani A. Awad, James L. McGrath
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
The vascular system plays a critical role in the progression and resolution of inflammation. The contributions of the vascular endothelium to these processes, however, vary with tissue and disease state. Recently, tissue chip models have emerged as p
Externí odkaz:
https://doaj.org/article/1d80af8fb7f54b139a781ccb8eb257fa
Autor:
H. Mark Kenney, Yue Peng, Kiana L. Chen, Raquel Ajalik, Lindsay Schnur, Ronald W. Wood, Edward M. Schwarz, Hani A. Awad
Publikováno v:
Bone Reports, Vol 16, Iss , Pp 101167- (2022)
Introduction: Micro-computed tomography (μCT) is a valuable imaging modality for longitudinal quantification of bone volumes to identify disease or treatment effects for a broad range of conditions that affect bone health. Complex structures, such a
Externí odkaz:
https://doaj.org/article/37ab4d2aae024d879b113243110fdcde
Autor:
Raquel E. Ajalik, Rahul G. Alenchery, John S. Cognetti, Victor Z. Zhang, James L. McGrath, Benjamin L. Miller, Hani A. Awad
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Human Microphysiological Systems (hMPS), otherwise known as organ- and tissue-on-a-chip models, are an emerging technology with the potential to replace in vivo animal studies with in vitro models that emulate human physiology at basic levels. hMPS p
Externí odkaz:
https://doaj.org/article/7d2bad37ea37494e8463c222c9b07b70
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Category: Midfoot/Forefoot; Other Introduction/Purpose: Progressive collapsing flatfoot deformity (PCFD) leads to a disruption of the medial peritalar ligaments with progressive loss of the medial arch and further valgus alignment of the subtalar and
Externí odkaz:
https://doaj.org/article/1a5e25b14be14d69a83ea8511883edc0
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Category: Hindfoot; Ankle Introduction/Purpose: Talar ANV, trauma, and implant failure or collapse after TAR are major challenges in foot and ankle surgery. Custom total talar implants are a promising option for such conditions and have shown promisi
Externí odkaz:
https://doaj.org/article/0fe5ce7dfbd44f70b260928b7e7e0ea9
Autor:
Elysia A. Masters, Gowrishankar Muthukrishnan, Lananh Ho, Ann Lindley Gill, Karen L. de Mesy Bentley, Chad A. Galloway, James L. McGrath, Hani A. Awad, Steven R. Gill, Edward M. Schwarz
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Staphylococcus aureus invasion of the osteocyte lacuno-canalicular network (OLCN) is a novel mechanism of bacterial persistence and immune evasion in chronic osteomyelitis. Previous work highlighted S. aureus cell wall transpeptidase, penicillin bind
Externí odkaz:
https://doaj.org/article/9f13972546dd407aa4bcffa9929fcc8f
Autor:
Margaret A. T. Freeberg, Youssef M. Farhat, Anas Easa, Jacob G. Kallenbach, Dominic W. Malcolm, Mark R. Buckley, Danielle S. W. Benoit, Hani A. Awad
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Injuries to flexor tendons can be complicated by fibrotic adhesions, which severely impair the function of the hand. Adhesions have been associated with TGF-β1, which causes upregulation of PAI-1, a master suppressor of protease activity, i
Externí odkaz:
https://doaj.org/article/e5cdfd5cb21341d4a50f60bcc3be2d10
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Drug repurposing offers an expedited and economical route to develop new clinical therapeutics in comparison to traditional drug development. Growth-based high-throughput screening is concomitant with drug repurposing and enables rapid ident
Externí odkaz:
https://doaj.org/article/1e0a50069cf744c4848bf014e566bb50