Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Hanhan Liu"'
Autor:
Xiaosha Wang, Layla Frühn, Panpan Li, Xin Shi, Nini Wang, Yuan Feng, Julia Prinz, Hanhan Liu, Verena Prokosch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The retina is part of the central nervous system (CNS). Neurons in the CNS and retinal ganglion cells lack the ability to regenerate axons spontaneously after injury. The intrinsic axonal growth regulators, their interaction and roles that e
Externí odkaz:
https://doaj.org/article/6a2c0980db42463898e1216a93964f68
Autor:
Xin Shi, Panpan Li, Marc Herb, Hanhan Liu, Maoren Wang, Xiaosha Wang, Yuan Feng, Tim van Beers, Ning Xia, Huige Li, Verena Prokosch
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-23 (2024)
Abstract Background NADPH oxidase (NOX), a primary source of endothelial reactive oxygen species (ROS), is considered a key event in disrupting the integrity of the blood-retinal barrier. Abnormalities in neurovascular-coupled immune signaling herald
Externí odkaz:
https://doaj.org/article/8cefb59a93cf49a6b18fe067964ea100
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 6170-6189 (2023)
Long non-coding RNAs (lncRNAs) participate in acute lung injury (ALI). However, their latent biological function and molecular mechanism have not been fully understood. In the present study, the global expression profiles of lncRNAs and mRNAs between
Externí odkaz:
https://doaj.org/article/158b9cec855441ac8005cfc22af22f32
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0297525 (2024)
Notch pathway has played a significant role in the pathophysiology of pulmonary hypertension (PH). However, the role of Jagged 2 (Jag2), one ligand of Notch, remains to be elucidated.Therefore, determining the contribution of Jag2 to PH and its impac
Externí odkaz:
https://doaj.org/article/15246b96d30443df8e3d3b7258dc5f53
Autor:
Hui Tao, Jia Tan, Hanchen Zhang, Hong Ren, Ziyi Cai, Hanhan Liu, Bingyu Wen, Jiaqi Du, Gaoyang Li, Shijie Chen, Haihua Xiao, Zhihong Deng
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract The cGAS‐STING pathway, as a vital innate immune signaling pathway, has attracted considerable attention in tumor immunotherapy research. However, STING agonists are generally incapable of targeting tumors, thus limiting their clinical app
Externí odkaz:
https://doaj.org/article/b881673f00de40cf8188ca368386c4fe
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115403- (2023)
Purpose: In this study, we aim to investigate the potential of nintedanib as a therapeutic approach to proliferative vitreoretinopathy (PVR), which is the leading cause of failure in retinal detachment repair. PVR is characterized by the epithelial-m
Externí odkaz:
https://doaj.org/article/2b15db3efcbb4d52aff7e65c9df100b0
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114543- (2023)
Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a key fibrosis pathogenesis in proliferative vitreoretinopathy (PVR). However, few medicines can prevent proliferative membranes and cell proliferation in the clinic
Externí odkaz:
https://doaj.org/article/df9540cab2394ce4bad5976356697d75
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 29 (2024)
Background: Although the current role of cytokines and neuroinflammation in glaucoma remains obscure, it represents an expanding field in research. The purpose of this study was to analyze cytokines in the aqueous humor (AH) of glaucoma patients and
Externí odkaz:
https://doaj.org/article/b4771009ca0d4b4f84a5c266843028c1
Autor:
Xiaosha Wang, Maoren Wang, Hanhan Liu, Karl Mercieca, Julia Prinz, Yuan Feng, Verena Prokosch
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13211 (2023)
Glaucoma is a leading cause of irreversible blindness worldwide. While intraocular pressure (IOP) presents a major risk factor, the underlying pathophysiology still remains largely unclear. The correlation between vascular abnormalities and glaucoma
Externí odkaz:
https://doaj.org/article/3f89a41084904e129bc37b06826e3418
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291836 (2023)
PurposeGlaucoma is a leading cause of irreversible blindness worldwide. Retinal ganglion cells (RGC), the neurons that connect the eyes to the brain, specifically die in glaucoma, leading to blindness. Elevated intraocular pressure (IOP) is the only
Externí odkaz:
https://doaj.org/article/7496b3af613c41d6b3104e23a8837f13