Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Hanhai Zeng"'
Autor:
Huaijun Chen, Chaoran Xu, Hanhai Zeng, Zhihua Zhang, Ning Wang, Yinghan Guo, Yonghe Zheng, Siqi Xia, Hang Zhou, Xiaobo Yu, Xiongjie Fu, Tianchi Tang, Xinyan Wu, Zihang Chen, Yucong Peng, Jing Cai, Jianru Li, Feng Yan, Chi Gu, Gao Chen, Jingyin Chen
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Subarachnoid hemorrhage (SAH) is an uncommon type of potentially fatal stroke. The pathophysiological mechanisms of brain injury remain unclear, which hinders the development of drugs for SAH. We aimed to investigate the pathophys
Externí odkaz:
https://doaj.org/article/4e90c1634dec43a8a8d3328197469c1d
Autor:
Junjie Cheng, Hanhai Zeng, Huaijun Chen, Linfeng Fan, Chaoran Xu, Huaping Huang, Tianchi Tang, Min Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Thrombocytopenia, characterized by a decrease in platelet count, is commonly observed in sepsis and COVID-19. In sepsis, thrombocytopenia can result from various mechanisms, including impaired platelet production in the bone marrow, accelerated plate
Externí odkaz:
https://doaj.org/article/36b5dffab3c141e1998a9562709b8d41
Autor:
Yi Zhang, Hanhai Zeng, Hang Zhou, Jingbo Li, Tingting Wang, Yinghan Guo, Lingxin Cai, Junwen Hu, Xiaotong Zhang, Gao Chen
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 22, p 7040 (2023)
Aneurysmal subarachnoid hemorrhage (aSAH) frequently causes long-term disability, but predicting outcomes remains challenging. Routine parameters such as demographics, admission status, CT findings, and blood tests can be used to predict aSAH outcome
Externí odkaz:
https://doaj.org/article/48e3d618645241c2888bc78f63be50f9
Autor:
Guangyu Ying, Wen Fang, Hanhai Zeng, Hongwen Ding, Huaijun Chen, Zhiqi Jiang, Lili Chen, Qiaoling Hu, Yongjian Zhu, Gao Chen
Publikováno v:
Materials & Design, Vol 227, Iss , Pp 111730- (2023)
Dural defects and subsequent leakage of cerebrospinal fluid (CSF) after neurosurgery are often associated with serious complications or even death. The associated surgical suture or sealant repair is often followed by pinhole leakage or a loose seal.
Externí odkaz:
https://doaj.org/article/cc98a301363644b38d6b7f845e14c074
Autor:
Hanhai Zeng, Huaijun Chen, Min Li, Jianfeng Zhuang, Yucong Peng, Hang Zhou, Chaoran Xu, Qian Yu, Xiongjie Fu, Shenglong Cao, Jing Cai, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Neuroinflammation and oxidative stress plays an important role in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). This study is the first to show that activation of autophagy protein nuclear recep
Externí odkaz:
https://doaj.org/article/d4653c589f4c45d483ca0e80f81a2ac4
Autor:
Xiongjie Fu, Guoyang Zhou, Xinyan Wu, Chaoran Xu, Hang Zhou, Jianfeng Zhuang, Yucong Peng, Yang Cao, Hanhai Zeng, Yin Li, Jianru Li, Liansheng Gao, Gao Chen, Lin Wang, Feng Yan
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background White matter injury (WMI) is a major neuropathological event associated with intracerebral hemorrhage (ICH). P2X purinoreceptor 4 (P2X4R) is a member of the P2X purine receptor family, which plays a crucial role in regulating WMI
Externí odkaz:
https://doaj.org/article/272022f71bab4ea99ba55e3592f3aacc
Autor:
Yonghe Zheng, Linfeng Fan, Siqi Xia, Qiguo Yang, Zhihua Zhang, Huaijun Chen, Hanhai Zeng, Xiongjie Fu, Yucong Peng, Chaoran Xu, Kaibo Yu, Fuyi Liu, Shenglong Cao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
AimThe complement cascade is activated and may play an important pathophysiologic role in brain injury after experimental intracerebral hemorrhage (ICH). However, the exact mechanism of specific complement components has not been well studied. This s
Externí odkaz:
https://doaj.org/article/6897474fe4d94742b36631ad3305e98e
Autor:
Yinghan Guo, Jiang Liu, Hanhai Zeng, Lingxin Cai, Tingting Wang, Xinyan Wu, Kaibo Yu, Yonghe Zheng, Huaijun Chen, Yucong Peng, Xiaobo Yu, Feng Yan, Shenglong Cao, Gao Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe relationship between neutrophil to lymphocyte ratio (NLR) and poor outcome of aneurysmal subarachnoid hemorrhage (aSAH) is controversial. We aim to evaluate the relationship between NLR on admission and the poor outcome after aSAH.Metho
Externí odkaz:
https://doaj.org/article/6609dfd1bb5d45eaae73743f949c9b87
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
AimPrevious studies have proved that inhibiting inflammasome activation provides neuroprotection against early brain injury (EBI) after subarachnoid hemorrhage (SAH), which is mainly focused on the microglial inflammatory response, but the potential
Externí odkaz:
https://doaj.org/article/4f432496440f436f86f78d5cd157c5ed
Autor:
Yucong Peng, Jianfeng Zhuang, Guangyu Ying, Hanhai Zeng, Hang Zhou, Yang Cao, Huaijun Chen, Chaoran Xu, Xiongjie Fu, Hangzhe Xu, Jianru Li, Shenglong Cao, Jingyin Chen, Chi Gu, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-20 (2020)
Abstract Background Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of stimulator of IFN genes (STING), an essential regulator to innate immunity, i
Externí odkaz:
https://doaj.org/article/c0dc07953fd740abb1e2fad8df00e887